Analysis of the interaction of the -1385A/G polymorphisms of FGF1 gene promoter and ApoE gene in Alzheimer's disease

Chinese Journal of Neurology

Volumn 39, Issue 2, 2006, Pages 89-91

  Yao, Li Fen ^a   Li, Ke Shen ^b   Zhang, Li Ming ^b   Wang, De Sheng ^b   Song, Lin ^b   Xie, Ning ^b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

Alzheimer disease; Apolipoproteins E; Fibroblast growth factor 1; Polymorphism, restriction fragment length

Indexed keywords

APOLIPOPROTEIN E; FIBROBLAST GROWTH FACTOR 1;

ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENETIC ASSOCIATION; GENOTYPE; HUMAN; POLYMERASE CHAIN REACTION; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

EID: 33746082795     PISSN: 10067876     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Kimura H, Tooyama I, McGeer PL Acidic FGF expression in the surroundings of senile plaques. Tohoku J Exp Med, 1994, 174; 279-293.
2. Eckenstein FP. Fibroblast growth factors in the nervous system. J Neurobiol, 1994, 25:1467-1480.
3. Myers RL, Poyson RA, Choton MA, et al. Gene structure and differential expression of acidic fibroblast growth factor mRNA; identification and distribution of four different transcripts. Oncogene, 1993, 8:341-349.
4. Tooyama I, Akiyama H, McGeer PL, et al. Acidic fibroblast growth factor-like immunoreactivity in brain of Alzheimer patients. Neurosci Lett, 1991, 121:155-158.
5. Thorns V, Masliah E. Evidence for neuroprotective effects of acidic fibroblast growth factor in Alzheimer disease. J Neuropathol Exp Neurol, 1999, 58:296-306.
6. Thorns V, Licastro F, Masliah E, et al. Locally reduced levels of acidic FGF lead to decreased expression of 28-kDa calbindin and contribute to the selective vulnerability of the neurons in the entorhinal cortex in Alzheimer' s disease. Neuropathology, 2001, 21:203-211.
7. Yoneyama T, Kasuya H, Onda H, et al. Association of positional and functional candidate genes FGF1, FBN2, and LOX on 5q31 with intracranial aneurysm. J Hum Genet, 2003, 48:309-314.
8. Chiu IM, Touhalisky K, Baran C. Multiple controlling mechanisms of FGF1 gene expression through multiple tissue-specific promoters. Prog Nucleic Acid Res Mol Biol, 2001, 70:155-174.
9. Poyson RA, Choton MA, Chlu LM. Regulation of a promoter of the fibroblast growth factor 1 gene in prostate and breast cancer cells. J Steroid Biochem Mol Biol, 1998, 66:93-103.
10. Yamagata H, Chen Y, Akatsu H, et al. Promoter polymorphism in fibroblast growth factor 1 gene increases risk of definite Alzheimer' s disease. Biochem Biophy Res Commun, 2004, 321:320-323.
11. Ueno S, Ito J, Nagayasu Y, et al. An acidic fibroblast growth factor-like factor secreted into the brain cell culture medium upregulates APOE synthesis, HDL secretion and cholesterol metabolism in rat astrocytes. Biochem Biophys Acta, 2002, 1589:261-272.
12. Tada T, Ito J, Asai M, et al. Fibroblast growth factor 1 is produced prior to apolipoprotein E in the astrocytes after cryo-injury of mouse brain. Neurochem Int, 2004, 45:23-30.