Identification of chitotriosidase isoforms in plasma of Gaucher disease patients by two dimensional gel electrophoresis

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1764, Issue 7, 2006, Pages 1292-1298

  Quintana, Lucía ^a   Monasterio, Alberto ^b   Escuredo, Kepa ^b   del Amo, Jokin ^b   Alfonso, Pilar ^a   Elortza, Felix ^c   Santa Cruz, Simon ^b   Simón, Laureano ^b   Martínez, Antonio ^b   Giraldo, Pilar ^a   Pocoví, Miguel ^a   Luis Castrillo, José ^d  

^a INSTITUTO ARAGONÉS DE CIENCIAS DE LA SALUD   (Spain)

^b Proteomika SL   (Spain)

^c CIC BIOGUNE   (Spain)

^d CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

2 DE; Biomarker; Chitotriosidase; Gaucher disease

Indexed keywords

CHITOTRIOSIDASE; ISOENZYME; PLASMA PROTEIN;

ADULT; ALLELE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BLOOD LEVEL; ENZYME LOCALIZATION; GAUCHER DISEASE; HOMOZYGOSITY; HUMAN; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING; WILD TYPE;

BLOTTING, WESTERN; CATALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GAUCHER DISEASE; GLYCOSYLATION; HEXOSAMINIDASES; HUMANS; ISOENZYMES; NEURAMINIDASE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 33746080044     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2006.05.009     Document Type: Article

References (17)

1. Beutler E., and Grabowski G.A. In: Scriver C.R., Beaudet A.L., Sly W.S., and Valle D. (Eds). The Metabolic and Molecular Basis of Inherited Disease. 8a ed. (2001), McGraw-Hill, New York 3635-3668
2. Hollak C.E.M., van Weely S., van Oers M.H.J., and Aerts J.M.F.G. Marked elevation of plasma chitotriosidase activity, a novel hallmark of Gaucher disease. J. Clin. Invest. 93 (1994) 491-502
3. Boot R.G., Renkema G.H., Verhoek M., Strijland A., Bliek J., de Meulemeester T.M.A.M.O., Mannens M.M.A.M., and Aerts J.M.F.G. The human chitotriosidase gene, nature of inherited enzyme deficiency. J. Biol. Chem. 273 (1998) 25680-25685
4. Renkema G.H., Boot R.G., Strijland A., Donker-Koopman W.E., Van den Berg M., Muijsers A.O., and Aerts J.M.F.G. Synthesis, sorting, and processing into distinct isoforms of human macrophage chitotriosidase. Eur. J. Biochem. 244 (1997) 279-285
5. Renkema G.H., Boot R.G., Muijsers A.O., Donker-Koopman W.E., and Aerts J.M.F.G. Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins. J. Biol. Chem. 270 (1995) 2198-2202
6. Giraldo P., Pocoví M., Pérez-Calvo J.I., Rubio-Félix D., and Giralt M. Report of the Spanish Gaucher's disease registry: clinical and genetic characteristics. Haematologica 85 (2000) 792-799
7. Raghavan S.S., Topol J., and Kolodny E.H. Leukocyte beta-glucosidase in homozygotes and heterozygotes for Gaucher disease. Am. J. Hum. Genet. 32 (1980) 158-173
8. Giraldo P., Cenarro A., Alfonso P., Pérez-Calvo J.I., Rubio-Félix D., Giralt M., and Pocoví M. Chitotriosidase genotype and plasma activity in patients with type 1 Gaucher's disease and their relatives (carriers and non-carriers). Haematologica 86 (2001) 977-984
9. Görg A., Obermaier C., Boguth G., Harder A., Scheibe B., Wildgruber R., and Weiss W. The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 21 (2000) 1037-1053
10. Brautbar A., Elstein D., Pines G., Abrahamov A., and Zimran A. Effect of enzyme replacement therapy on gammopathies in Gaucher disease. Blood Cells, Mol. Dis. 32 (2004) 214-217
11. Sevchenko A., Wilm M., Vorm O., and Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68 (1996) 850-858
12. Gobom J., Nordhoff E., Mirgorodskaya E., Ekman R., and Roepstorff P. Sample purification and preparation technique based on nano-scale reversed-phase columns for the sensitive analysis of complex peptide mixtures by matrix-assisted laser desorption/ionization mass spectrometry. J. Mass Spectrom. 34 (1999) 105-116
13. Larsen M.R., Cordwell S., and Roepstorff P. Graphite powder as an alternative or supplement to reversed-phase material for desalting and concentration of peptide mixtures prior to matrix-assisted laser desorption/ionization-mass spectrometry. Proteomics 2 (2002) 1277-1287
14. Rosalki S.B., and Ying Foo A. Incubation with neuraminidase and affinity electrophoresis with wheat-germ lectin compared for separating and quantifying alkaline phosphatase isoenzymes in plasma. Clin. Chem. 31 (1985) 1198-1200
15. Pennington K., McGregor E., Beasley C.L., Everall I., Cotter D., and Dunn M.J. Optimization of the first dimension for separation by two-dimensional gel electrophoresis of basic proteins from human brain tissue. Proteomics 4 (2004) 27-30
16. Bae S.H., Harris A.G., Hains P.G., Chen H., Garfin D.E., Hazell S.L., Paik Y.K., Walsh B.J., and Cordwell S.J. Strategies for the enrichment and identification of basic proteins in proteome projects. Proteomics 3 (2003) 569-579
17. Fuhrman J.A., Lee J., and Dalamagas D. Structure and function of a family of chitinase isozymes from Brugian microfilariae. Exp. Parasitol. 80 (1995) 672-680