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Volumn 176, Issue 1-2, 2006, Pages 125-133

Dynamics of interferon-β modulated mRNA biomarkers in multiple sclerosis patients with anti-interferon-β neutralizing antibodies

Author keywords

Antibodies; Gene expression; Interferons; Multiple sclerosis; Pharmacodynamics

Indexed keywords

BETA 2 MICROGLOBULIN; BETA1A INTERFERON; BIOLOGICAL MARKER; COMPLEMENTARY DNA; INTERFERON ANTIBODY; INTERFERON BETA NEUTRALIZING ANTIBODY; MESSENGER RNA; MYXOVIRUS RESISTANCE PROTEIN; MYXOVIRUS RESISTANCE PROTEIN A; MYXOVIRUS RESISTANCE PROTEIN B; RNA; STAT1 PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

EID: 33746078848     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2006.03.019     Document Type: Article
Times cited : (41)

References (33)
  • 1
    • 2442417839 scopus 로고    scopus 로고
    • Interferon-alpha and ribavirin therapy on chronic hepatitis C virus infection: the experience of Rio Grande do Sul State Health Department, Brazil
    • Alves A.V., de Azevedo A.P., Perin C., Ramos G.Z., Brandao A.B., de Mattos A.A., and de Almeida P.R. Interferon-alpha and ribavirin therapy on chronic hepatitis C virus infection: the experience of Rio Grande do Sul State Health Department, Brazil. Arq. Gastroenterol. 40 (2003) 227-232
    • (2003) Arq. Gastroenterol. , vol.40 , pp. 227-232
    • Alves, A.V.1    de Azevedo, A.P.2    Perin, C.3    Ramos, G.Z.4    Brandao, A.B.5    de Mattos, A.A.6    de Almeida, P.R.7
  • 2
    • 28044463388 scopus 로고    scopus 로고
    • Upregulation of TRAIL expression on human T lymphocytes by interferon beta and glatiramer acetate
    • Arbour N., Rastikerdar E., McCrea E., Lapierre Y., Dorr J., Bar-Or A., and Antel J.P. Upregulation of TRAIL expression on human T lymphocytes by interferon beta and glatiramer acetate. Mult. Scler. 11 (2005) 652-657
    • (2005) Mult. Scler. , vol.11 , pp. 652-657
    • Arbour, N.1    Rastikerdar, E.2    McCrea, E.3    Lapierre, Y.4    Dorr, J.5    Bar-Or, A.6    Antel, J.P.7
  • 3
    • 0034691518 scopus 로고    scopus 로고
    • Interferon beta neutralizing antibodies in multiple sclerosis: neutralizing activity and cross-reactivity with three different preparations
    • Bertolotto A., Malucchi S., Milano E., Castello A., Capobianco M., and Mutani R. Interferon beta neutralizing antibodies in multiple sclerosis: neutralizing activity and cross-reactivity with three different preparations. Immunopharmacology 48 (2000) 95-100
    • (2000) Immunopharmacology , vol.48 , pp. 95-100
    • Bertolotto, A.1    Malucchi, S.2    Milano, E.3    Castello, A.4    Capobianco, M.5    Mutani, R.6
  • 4
    • 0035480227 scopus 로고    scopus 로고
    • Evaluation of bioavailability of three types of IFNbeta in multiple sclerosis patients by a new quantitative-competitive-PCR method for MxA quantification
    • Bertolotto A., Gilli F., Sala A., Audano L., Castello A., Magliola U., Melis F., and Giordana M.T. Evaluation of bioavailability of three types of IFNbeta in multiple sclerosis patients by a new quantitative-competitive-PCR method for MxA quantification. J. Immunol. Methods 256 (2001) 141-152
    • (2001) J. Immunol. Methods , vol.256 , pp. 141-152
    • Bertolotto, A.1    Gilli, F.2    Sala, A.3    Audano, L.4    Castello, A.5    Magliola, U.6    Melis, F.7    Giordana, M.T.8
  • 7
    • 0033775615 scopus 로고    scopus 로고
    • Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
    • Bustin S.A. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J. Mol. Endocrinol. 25 (2000) 169-193
    • (2000) J. Mol. Endocrinol. , vol.25 , pp. 169-193
    • Bustin, S.A.1
  • 8
    • 0032417696 scopus 로고    scopus 로고
    • Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
    • Der S.D., Zhou A., Williams B.R., and Silverman R.H. Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 15623-15628
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 15623-15628
    • Der, S.D.1    Zhou, A.2    Williams, B.R.3    Silverman, R.H.4
  • 9
    • 0036341053 scopus 로고    scopus 로고
    • Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1
    • Feng X., Petraglia A.L., Chen M., Byskosh P.V., Boos M.D., and Reder A.T. Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1. J. Neuroimmunol. 129 (2002) 205-215
    • (2002) J. Neuroimmunol. , vol.129 , pp. 205-215
    • Feng, X.1    Petraglia, A.L.2    Chen, M.3    Byskosh, P.V.4    Boos, M.D.5    Reder, A.T.6
  • 11
    • 22044436956 scopus 로고    scopus 로고
    • Interferon beta-1a in MS: results following development of neutralizing antibodies in PRISMS
    • Francis G.S., Rice G.P., and Alsop J.C. Interferon beta-1a in MS: results following development of neutralizing antibodies in PRISMS. Neurology 65 (2005) 48-55
    • (2005) Neurology , vol.65 , pp. 48-55
    • Francis, G.S.1    Rice, G.P.2    Alsop, J.C.3
  • 12
    • 31644440262 scopus 로고    scopus 로고
    • Biological markers of interferon-therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1
    • Gilli F., Marnetto F., Caldano M., Sala A., Malucchi S., Capobianco M., and Bertolotto A. Biological markers of interferon-therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1. Mult. Scler. 12 (2006) 47-57
    • (2006) Mult. Scler. , vol.12 , pp. 47-57
    • Gilli, F.1    Marnetto, F.2    Caldano, M.3    Sala, A.4    Malucchi, S.5    Capobianco, M.6    Bertolotto, A.7
  • 13
    • 0024456475 scopus 로고
    • The role of mRNA and protein stability in gene expression
    • Hargrove J.L., and Schmidt F.H. The role of mRNA and protein stability in gene expression. FASEB J. 3 (1989) 2360-2370
    • (1989) FASEB J. , vol.3 , pp. 2360-2370
    • Hargrove, J.L.1    Schmidt, F.H.2
  • 16
    • 0028008814 scopus 로고
    • Comparative efficacy of interferon alfa in cirrhotic and noncirrhotic patients with non-A, non-B, C hepatitis. Le Groupe Francais pour l'Etude du Traitement des Hepatites Chroniques NANB/C
    • Jouet P., Roudot-Thoraval F., Dhumeaux D., and Metreau J.M. Comparative efficacy of interferon alfa in cirrhotic and noncirrhotic patients with non-A, non-B, C hepatitis. Le Groupe Francais pour l'Etude du Traitement des Hepatites Chroniques NANB/C. Gastroenterology 106 (1994) 686-690
    • (1994) Gastroenterology , vol.106 , pp. 686-690
    • Jouet, P.1    Roudot-Thoraval, F.2    Dhumeaux, D.3    Metreau, J.M.4
  • 17
    • 0037299113 scopus 로고    scopus 로고
    • Current therapy for hepatitis C: pegylated interferon and ribavirin
    • McHutchison J.G., and Fried M.W. Current therapy for hepatitis C: pegylated interferon and ribavirin. Clin. Liver Dis. 7 (2003) 149-161
    • (2003) Clin. Liver Dis. , vol.7 , pp. 149-161
    • McHutchison, J.G.1    Fried, M.W.2
  • 18
    • 33746048346 scopus 로고    scopus 로고
    • A study of the effect of gender on interferon beta-1a (Avonex 30 mcg) treatment in patients with multiple sclerosis
    • Munschauer F.E., Herndon R.M., Sandrock A.W., Tsao E., B. J.E., and Stubbendick A. A study of the effect of gender on interferon beta-1a (Avonex 30 mcg) treatment in patients with multiple sclerosis. Mult. Scler. 11 (2005) S78
    • (2005) Mult. Scler. , vol.11
    • Munschauer, F.E.1    Herndon, R.M.2    Sandrock, A.W.3    Tsao, E.4    B., J.E.5    Stubbendick, A.6
  • 19
    • 0028076001 scopus 로고
    • Quantitation of interferon-induced Mx protein in whole blood lysates by an immunochemiluminescent assay: elimination of protease activity of cell lysates in toto
    • Oh S.K., Luhowskyj S., Witt P., Ritch P., Reitsma D., Towbin H., Horisberger M., von Wussow P., and Bluestein B. Quantitation of interferon-induced Mx protein in whole blood lysates by an immunochemiluminescent assay: elimination of protease activity of cell lysates in toto. J. Immunol. Methods 176 (1994) 79-91
    • (1994) J. Immunol. Methods , vol.176 , pp. 79-91
    • Oh, S.K.1    Luhowskyj, S.2    Witt, P.3    Ritch, P.4    Reitsma, D.5    Towbin, H.6    Horisberger, M.7    von Wussow, P.8    Bluestein, B.9
  • 20
    • 0242489120 scopus 로고    scopus 로고
    • An improved ELISA for screening for neutralizing anti-IFN-beta antibodies in MS patients
    • Pachner A.R. An improved ELISA for screening for neutralizing anti-IFN-beta antibodies in MS patients. Neurology 61 (2003) 1444-1446
    • (2003) Neurology , vol.61 , pp. 1444-1446
    • Pachner, A.R.1
  • 21
    • 0242404144 scopus 로고    scopus 로고
    • Measurement of MxA mRNA or protein as a biomarker of IFNbeta bioactivity: detection of antibody-mediated decreased bioactivity (ADB)
    • Pachner A.R., Bertolotto A., and Deisenhammer F. Measurement of MxA mRNA or protein as a biomarker of IFNbeta bioactivity: detection of antibody-mediated decreased bioactivity (ADB). Neurology 61 (2003) S24-S26
    • (2003) Neurology , vol.61
    • Pachner, A.R.1    Bertolotto, A.2    Deisenhammer, F.3
  • 22
    • 23144458935 scopus 로고    scopus 로고
    • The importance of measuring IFNbeta bioactivity: monitoring in MS patients and the effect of anti-IFNbeta antibodies
    • Pachner A.R., Dail D., Pak E., and Narayan K. The importance of measuring IFNbeta bioactivity: monitoring in MS patients and the effect of anti-IFNbeta antibodies. J. Neuroimmunol. 166 (2005) 180-188
    • (2005) J. Neuroimmunol. , vol.166 , pp. 180-188
    • Pachner, A.R.1    Dail, D.2    Pak, E.3    Narayan, K.4
  • 24
    • 0034744952 scopus 로고    scopus 로고
    • Interferon-beta (INF-beta) antibodies in interferon-beta1a- and interferon-beta1b-treated multiple sclerosis patients. Prevalence, kinetics, cross-reactivity, and factors enhancing interferon-beta immunogenicity in vivo
    • Perini P., Facchinetti A., Bulian P., Massaro A.R., Pascalis D.D., Bertolotto A., Biasi G., and Gallo P. Interferon-beta (INF-beta) antibodies in interferon-beta1a- and interferon-beta1b-treated multiple sclerosis patients. Prevalence, kinetics, cross-reactivity, and factors enhancing interferon-beta immunogenicity in vivo. Eur. Cytokine Netw. 12 (2001) 56-61
    • (2001) Eur. Cytokine Netw. , vol.12 , pp. 56-61
    • Perini, P.1    Facchinetti, A.2    Bulian, P.3    Massaro, A.R.4    Pascalis, D.D.5    Bertolotto, A.6    Biasi, G.7    Gallo, P.8
  • 25
    • 0345601517 scopus 로고    scopus 로고
    • Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
    • PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group
    • PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. Lancet 352 (1998) 1498-1504
    • (1998) Lancet , vol.352 , pp. 1498-1504
  • 27
    • 0029912760 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteers
    • Salmon P., Le Cotonnec J.Y., Galazka A., Abdul-Ahad A., and Darragh A. Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteers. J. Interferon Cytokine Res. 16 (1996) 759-764
    • (1996) J. Interferon Cytokine Res. , vol.16 , pp. 759-764
    • Salmon, P.1    Le Cotonnec, J.Y.2    Galazka, A.3    Abdul-Ahad, A.4    Darragh, A.5
  • 30
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis: I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
    • The IFNB Multiple Sclerosis Study Group
    • The IFNB Multiple Sclerosis Study Group. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis: I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 43 (1993) 655-661
    • (1993) Neurology , vol.43 , pp. 655-661
  • 31
    • 0005489101 scopus 로고    scopus 로고
    • Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: experience during the first three years
    • The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group
    • The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group. Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: experience during the first three years. Neurology 47 (1996) 889-894
    • (1996) Neurology , vol.47 , pp. 889-894


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