Sudden unexpected death in infancy and childhood due to undiagnosed neoplasia: An autopsy study

American Journal of Forensic Medicine and Pathology

Volumn 27, Issue 1, 2006, Pages 64-69

  Somers, Gino R ^a,b   Smith, Charles R ^a,b   Perrin, Donald G ^a,b   Wilson, Gregory J ^a,b   Taylor, Glenn P ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Ministry of Community Safety and Correctional Services   (Canada)

Author keywords

Childhood; Gastric carcinoma; Infancy; Leukemia; Lymphoma; Medulloblastoma; Neoplasia; Sudden unexpected death; Wilms tumor

Indexed keywords

ACUTE LEUKEMIA; ARTICLE; AUTOPSY; CHILD; CHILDHOOD; FEMALE; FIBROELASTOMA; GLIOMA; HEMOPERITONEUM; HUMAN; INFANCY; INFANT; LYMPHOBLASTOMA; MALE; MEDULLOBLASTOMA; NEOPLASM; NEPHROBLASTOMA; RHABDOMYOMA; STOMACH CARCINOMA; SUDDEN DEATH; ADOLESCENT; CANADA; FORENSIC MEDICINE; INCIDENCE; MORTALITY; NEWBORN; PRESCHOOL CHILD;

ADOLESCENT; CANADA; CHILD; CHILD, PRESCHOOL; DEATH, SUDDEN; FEMALE; FORENSIC MEDICINE; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; MALE; NEOPLASMS;

EID: 33746035365     PISSN: 01957910     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.paf.0000203267.91806.ed     Document Type: Article

References (54)

1. Paul O, Schatz M. On sudden death. Circulation. 1971;43:7-10.
2. Neuspiel DR, Kuller LH. Sudden and unexpected natural death in childhood and adolescence. JAMA. 1985;254:1321-1325.
3. Moritz AR, Zamcheck N. Sudden and unexpected deaths of young soldiers: diseases responsible for such deaths during World War II. Arch Pathol. 1946;42:459-494.
4. Hauck FR. Changing epidemiology. In: Byard RW, Krous HF, eds. Sudden Infant Death Syndrome: Problems, Progress and Possibilities. London: Arnold; 2001:31-57.
5. Berry CL. Causes of sudden natural death in infancy and childhood. In: Mason JK, ed. Paediatric Forensic Medicine and Pathology. London: Chapman and Hall Medical; 1989:165-177.
6. Norman MG, Taylor GP, Clarke LA. Sudden, unexpected, natural death in childhood. Pediatr Pathol. 1990;10:769-784.
7. Keeling JW, Knowles SA. Sudden death in childhood and adolescence. J Pathol. 1989;159:221-224.
8. Helweg-Larsen K, Garde E. Sudden natural death in childhood: a review of forensic autopsy protocols in cases of sudden death between the ages of one and five years, 1982-1991, with a special view to sudden unexplained death. Acta Paediatr. 1993;82:975-978.
9. Rajs J, Rasten-Almqvist P, Nennesmo I. Unexpected death in two young infants mimics SIDS: autopsies demonstrate tumors of medulla and heart. Am J Forensic Med Pathol. 1997;18:384-390.
10. Byard RW, Bourne AJ, Hanieh A. Sudden and unexpected death due to hemorrhage from occult central nervous system lesions: a pediatric autopsy study. Pediatr Neurosurg. 1991;17:88-94.
11. Duray PH, Mark EJ, Barwick KW, et al. Congenital polycystic tumor of the atrioventricular node: autopsy study with immunohistochemical findings suggesting endodermal derivation. Arch Pathol Lab Med. 1985;109:30-34.
12. Burke AP, Anderson PG, Virmani R, et al. Tumor of the atrioventricular nodal region: a clinical and immunohistochemical study. Arch Pathol Lab Med. 1990;114:1057-1062.
13. Burke AP, Virmani R. Cardiac rhabdomyoma: a clinicopathologic study. Mod Pathol. 1991;4:70-74.
14. Matsuura H, Kitazawa Y, Tanaka M, et al. Pituitary adenoma and unexpected sudden infant death: a case report. Med Pediatr Oncol. 1994;22:283-286.
15. DiMaio SM, DiMaio VJ, Kirkpatrick JB. Sudden, unexpected deaths due to primary intracranial neoplasms. Am J Forensic Med Pathol. 1980;1:29-45.
16. Nelson J, Frost JL, Schochet SS Jr. Sudden, unexpected death in a 5-year-old boy with an unusual primary intracranial neoplasm: ganglioglioma of the medulla. Am J Forensic Med Pathol. 1987;8:148-152.
17. Gleckman AM, Smith TW. Sudden unexpected death from primary posterior fossa tumors. Am J Forensic Med Pathol. 1998;19:303-308.
18. Byard RW. Sudden Death in Infancy and Childhood. 2nd ed. Cambridge: Cambridge University Press; 2004:643.
19. Gezelius C, Eriksson A. Neoplastic disease in a medicolegal autopsy material: a retrospective study in northern Sweden. Z Rechtsmed. 1988;101:115-130.
20. Luke JL, Helpern M. Sudden unexpected death from natural causes in young adults: a review of 275 consecutive autopsied cases. Arch Pathol. 1968;85:10-17.
21. Byard RW. Significant coincidental findings at autopsy in accidental childhood death. Med Sci Law. 1997;37:259-262.
22. Hutchins KD, Dickson D, Hameed M, et al. Sudden death in a child due to an intrathoracic paraganglioma. Am J Forensic Med Pathol. 1999;20:338-342.
23. Kaminsky RA. Pathologic quiz case: an exceedingly rare cause of sudden cardiac death. Arch Pathol Lab Med. 2001;125:573-574.
24. Burke AP, Afzal MN, Barnett DS, et al. Sudden death after a cold drink: case report. Am J Forensic Med Pathol. 1999;20:37-39.
25. Swalwell CI. Benign intracardiac teratoma: a case of sudden death. Arch Pathol Lab Med. 1993;117:739-742.
26. Whybourne A, Zillman MA, Miliauskas J, et al. Sudden and unexpected infant death due to occult lymphoblastic leukaemia. J Clin Forensic Med. 2001;8:160-162.
27. Bohm N, Krebs G. Solitary rhabdomyoma of the heart: clinically silent case with sudden, unexpected death in an 11-month-old boy. Eur J Pediatr. 1980;134:167-172.
28. Violette EJ, Hardin NJ, McQuillen EN. Sudden unexpected death due to asymptomatic cardiac rhabdomyoma. J Forensic Sci. 1981;26:599-604.
29. Lunetta P, Karikoski R, Penttila A, et al. Sudden death associated with a multifocal type II hemangioendothelioma of the liver in a 3-month-old infant. Am J Forensic Med Pathol. 2004;25:56-59.
30. Matturri L, Ottaviani G, Rossi L. Sudden and unexpected infant death due to an hemangioendothelioma located in the medulla oblongata. Adv Clin Pathol. 1999;3:29-33.
31. Meissner C, Minnasch P, Gafumbegete E, et al. Sudden unexpected infant death due to fibroma of the heart. J Forensic Sci. 2000;45:731-733.
32. Perrot LJ. Malignant hemangioendothelioma: a case of sudden unexpected death in infancy. Am J Forensic Med Pathol. 1997;18:96-99.
33. Zakowski MF, Edwards RH, McDonough ET. Wilms' tumor presenting as sudden death due to tumor embolism. Arch Pathol Lab Med. 1990;114:605-608.
34. Siboni A, Simonsen J. Sudden unexpected natural death in young persons. Forensic Sci Int. 1986;31:159-166.
35. Cina SJ, Smialek JE, Burke AP, et al. Primary cardiac tumors causing sudden death: a review of the literature. Am J Forensic Med Pathol. 1996;17:271-281.
36. Gowda RM, Khan IA, Nair CK, et al. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am Heart J. 2003;146:404-410.
37. Amr SS, Abu al Ragheb SY. Sudden unexpected death due to papillary fibroma of the aortic valve: report of a case and review of the literature. Am J Forensic Med Pathol. 1991;12:143-148.
38. Agaimy A, Mandl L. [Papillary fibroelastoma of the aortic valve coincident with a cystic tumor of the atrioventricular node]. Pathologe. 2000;21:250-254.
39. Prahlow JA, Barnard JJ. Sudden death due to obstruction of coronary artery ostium by aortic valve papillary fibroelastoma. Am J Forensic Med Pathol. 1998;19:162-165.
40. Bussani R, Silvestri F. Images in cardiovascular medicine: sudden death in a woman with fibroelastoma of the aortic valve chronically occluding the right coronary ostium. Circulation. 1999;100:2204.
41. Seib HJ, Wildenauer M, Luther M, et al. [Papillary fibroelastoma of the aortic valve: sudden death caused by an uncommon tumor of the heart]. Z Kardiol. 1984;73:409-413.
42. Levin H, Bursztein S, Heifetz M. Cardiac arrest in a child with an anterior mediastinal mass. Anesth Analg. 1985;64:1129-1130.
43. Yamashita M, Chin I, Horigome H, et al. Sudden fatal cardiac arrest in a child with an unrecognized anterior mediastinal mass. Resuscitation. 1990;19:175-177.
44. Keon TP. Death on induction of anesthesia for cervical node biopsy. Anesthesiology. 1981;55:471-472.
45. Oeberst JL, Barnard JJ, Prahlow JA. Sudden death due to undiagnosed Wilms' tumor in an adult. J Forensic Sci. 2002;47:638-639.
46. Davidoff AM, Soutter AD, Shochat SJ. Wilms tumor presenting with abdominal pain: a special subgroup of patients. Ann Surg Oncol. 1998;5:213-215.
47. Futrell JW, Filston HC, Reid JD. Rupture of a renal cell carcinoma in a child: five-year tumor-free survival and literature review. Cancer. 1978;41:1565-1570.
48. Siegel SE, Hays DM, Romansky S, et al. Carcinoma of the stomach in childhood. Cancer. 1976;38:1781-1784.
49. Schwartz MG, Sgaglione NA. Gastric carcinoma in the young: overview of the literature. Mt Sinai J Med. 1984;51:720-723.
50. Brumback RA, Gerber JE, Hicks DG, et al. Adenocarcinoma of the stomach following irradiation and chemotherapy for lymphoma in young patients. Cancer. 1984;54:994-998.
51. Michalek J, Kopecna L, Tuma J, et al. Gastric carcinoma in a 9-year- old boy. Pediatr Hematol Oncol. 2000;17:511-515.
52. Coffin CM, Papuan AL. Polyps and neoplasms of the gastrointestinal tract in childhood and adolescence. Perspect Pediatr Pathol. 1997;20:127-171.
53. Varley JM, McGown G, Thorncroft M, et al. An extended Li-Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53. J Med Genet. 1995;32:942-955.
54. Kaste SC, Marina N, Fryrear R, et al. Peritoneal metastases in children with cancer. Cancer. 1998;83:385-390