Inhibitory effect of anethole on T-lymphocyte proliferation and interleukin-2 production through down-regulation of the NF-AT and AP-1

Toxicology in Vitro

Volumn 20, Issue 7, 2006, Pages 1098-1105

  Yea, Sung Su ^a   Jeong, Haeng Soon ^a   Choi, Chun Yeon ^a   Park, Kyung Ran ^a   Oh, Sangtaek ^a   Shin, Jae Gook ^a   Yun, Chul Ho ^b  

^a Inje University   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Activator protein 1 (AP 1); Anethole; Interleukin 2 (IL 2); Nuclear factor of activated T cells (NF AT)

Indexed keywords

ALKOXYBENZENE DERIVATIVE; ANETHOLE; CONCANAVALIN A; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; IONOMYCIN; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; OCTAMER BINDING PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GEL MOBILITY SHIFT ASSAY; IMMUNOMODULATION; IMMUNOPHARMACOLOGY; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHARMACODYNAMICS; PROTEIN BINDING; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; T LYMPHOCYTE; TRANSCRIPTION REGULATION;

ANIMALS; ANISOLES; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; CONCANAVALIN A; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INTERLEUKIN-2; IONOMYCIN; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED STRAINS; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; OCTAMER TRANSCRIPTION FACTOR-6; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1;

EID: 33746010303     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2006.01.020     Document Type: Article

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