Azithromycin-induced QT prolongation in elderly patient

Acta Biomedica de l'Ateneo Parmense

Volumn 77, Issue 1, 2006, Pages

  Russo, Vincenzo ^a   Puzio, Gianfranco ^a   Siniscalchi, Nicola ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Azithromycin; Elderly; QT prolongation

Indexed keywords

AZITHROMYCIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CEFTRIAXONE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; MAGNESIUM SULFATE; SPIRONOLACTONE;

AGED; ANAMNESIS; ARTERIAL GAS; ARTICLE; BLOOD CULTURE; BLOOD PRESSURE MEASUREMENT; BREATHING RATE; CARDIOVASCULAR RISK; CASE REPORT; CLINICAL FEATURE; COMMUNITY ACQUIRED PNEUMONIA; CONGESTIVE CARDIOMYOPATHY; DISEASE ASSOCIATION; ELECTROCARDIOGRAPHY; HEART FAILURE; HEART RATE; HEART VENTRICLE TACHYCARDIA; HIGH RISK PATIENT; HOSPITAL ADMISSION; HUMAN; LEUKOCYTE COUNT; MALE; QT INTERVAL; QT PROLONGATION; SPUTUM CULTURE; STRESS ECHOCARDIOGRAPHY; TELEMETRY; TEMPERATURE MEASUREMENT; THORAX RADIOGRAPHY; TREATMENT WITHDRAWAL;

AGED; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; ELECTROCARDIOGRAPHY; HEART VENTRICLES; HUMANS; MALE; TIME FACTORS;

EID: 33745998836     PISSN: 03924203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Rubinstein E. Comparative safety of the different macrolides. Int J Antimicrob Agents 2001; 18 Suppl 1: S71-6.
2. Brandriss MW, Richardson WS, Barold SS. Erythromycin-induced QT prolongation and polymorphic ventricular tachycardia (torsades de pointes): case report and review. Clin Infect Dis 1994; 18: 995-8.
3. Lee KL, Jim MH, Tang SC, Tai YT. QT prolongation and Torsades de Pointes associated with clarithromycin. Am J Med 1998; 104: 395-6.
4. Woywodt A, Grommas U, Buth W, Rafflenbeul W. QT prolongation due to roxithromycin. Postgrad Med J 2000; 76: 651-3.
5. Milberg P, Eckardt L, Bruns HJ, et al. Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early after depolarizations and torsade de pointes. J Pharmacol Exp Ther 2002; 303: 218-25.
6. Samarendra P, Kumari S, Evans SJ, et al. QT prolongation associated with azithromycin/amiodarone combination. Pacing Clin Electrophysiol 2001; 24: 1572-4.
7. Arellano-Rodrigo E, Garcia A, Mont L, Roque M. Torsade de pointes and cardiorespiratory arrest induced by azithromycin in a patient with congenital long QT syndrome. Med Clin (Barc) 2001; 117: 118-9.
8. Strle F, Maraspin V. Is azithromycin treatment associated with prolongation of the Q/Tc interval? Wien Klin Wochenschr 2002; 114 (10-11): 396-9.