The cannabinoid CB2 receptor inverse agonist JTE-907 suppresses spontaneous itch-associated responses of NC mice, a model of atopic dermatitis

European Journal of Pharmacology

Volumn 542, Issue 1-3, 2006, Pages 179-183

  Maekawa, Tatsuya ^a,b   Nojima, Hiroshi ^a,c   Kuraishi, Yasushi ^a   Aisaka, Kazuo ^b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b JAPAN TOBACCO INC   (Japan)

^c OHU UNIVERSITY   (Japan)

Author keywords

Cannabinoid CB2 receptor; Itch associated response; NC mouse

Indexed keywords

ANTIPRURITIC AGENT; BETAMETHASONE VALERATE; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; JTE 907; N (BENZO[1,3]DIOXOL 5 YLMETHYL) 7 METHOXY 2 OXO 8 PENTYLOXY 1,2 DIHYDROQUINOLINE 3 CARBOXAMIDE; TACROLIMUS; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; QUINOLONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; MALE; MOUSE; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; PRURITUS; SCRATCHING; SKIN DISEASE; SKIN INFLAMMATION; WEIGHT GAIN; WEIGHT REDUCTION; ANIMAL; ANIMAL BEHAVIOR; BODY WEIGHT; DOSE RESPONSE; DRUG POTENTIATION; HOSPITALIZATION; INNERVATION; MOUSE STRAIN; ORAL DRUG ADMINISTRATION; PATHOLOGY; PATHOPHYSIOLOGY; SKIN;

ADMINISTRATION, ORAL; ANIMALS; BEHAVIOR, ANIMAL; BETAMETHASONE 17-VALERATE; BODY WEIGHT; DERMATITIS, ATOPIC; DIOXOLES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOCORTICOIDS; IMMUNOSUPPRESSIVE AGENTS; MALE; MICE; MICE, INBRED STRAINS; PRURITUS; QUINOLONES; RECEPTOR, CANNABINOID, CB2; SEVERITY OF ILLNESS INDEX; SKIN; TACROLIMUS;

EID: 33745997333     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.05.040     Document Type: Article

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