Thiazide diuretics for hypertension: Prescribing practices and predictors of use in 194,761 elderly patients with hypertension

American Journal Geriatric Pharmacotherapy

Volumn 4, Issue 2, 2006, Pages 161-167

  Tu, Karen ^a,b   Campbell, Norman R C ^c   Chen, Zhongliang ^a   McAlister, Finlay A ^d  

^a INSTITUTE FOR CLINICAL EVALUATIVE SCIENCES   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

antihypertensives; elderly; prescribing patterns; thiazides

Indexed keywords

ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CHLORTALIDONE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROCHLOROTHIAZIDE; INDAPAMIDE; THIAZIDE DIURETIC AGENT;

AGE; AGED; ARTICLE; CANADA; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA BASE; DIABETES MELLITUS; DRUG CHOICE; DRUG USE; FEMALE; FUNDING; GENDER; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; POPULATION RESEARCH; PRESCRIPTION; PRIORITY JOURNAL; SCORING SYSTEM; SOCIAL STATUS;

AGED; AGED, 80 AND OVER; ANTIHYPERTENSIVE AGENTS; COHORT STUDIES; COMORBIDITY; DIABETES COMPLICATIONS; DIURETICS; DRUG UTILIZATION; FEMALE; HUMANS; HYPERTENSION; MALE; PHYSICIAN'S PRACTICE PATTERNS; SOCIOECONOMIC FACTORS; THIAZIDES;

EID: 33745963733     PISSN: 15435946     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjopharm.2006.06.004     Document Type: Article

References (32)

1. Joffres M.R., Hamer P., MacLean D.R., et al. Distribution of blood pressure and hypertension in Canada and the United States. Am J Hypertens 14 (2001) 1099-1105
2. [published correction appears in Lancet. 2003;361:1060]. Lewington S., Clarke R., Qizilbash N., et al., Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: A metaanalysis of individual data for one million adults in 61 prospective studies. Lancet 360 (2002) 1903-1913
3. [published correction appears in Lancet. 2001;357:724]. Staessen J.A., Gasowski J., Wang J.G., et al. Risks of untreated and treated isolated systolic hypertension in the elderly: Meta-analysis of outcome trials. Lancet 355 (2000) 865-872
4. Gueyffier F., Bulpitt C., Boissel J.P., et al., INDANA Group. Antihypertensive drugs in very old people: A subgroup meta-analysis of randomised controlled trials. Lancet 353 (1999) 793-796
5. Wong N.D., Thakral G., Franklin S.S., et al. Preventing heart disease by controlling hypertension: Impact of hypertensive subtype, stage, age, and sex. Am Heart J 145 (2003) 888-895
6. Chobanian A.V., Bakris G.L., Black H.R., et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The JNC 7 Report. JAMA 289 (2003) 2560-2572
7. Available at:. Canadian Hypertension Guidelines. 2005 Canadian recommendations for the management of hypertension. Accessed (May 22, 2006). http://wwwhypertension.ca/Documentation/Recommandation05_va.pdf
8. Psaty B.M., Manolio T.A., Smith N.L., et al., Cardiovascular Health Study. Time trends in high blood pressure control and the use of antihypertensive medications in older adults: The Cardiovascular Health Study. Arch Intern Med 162 (2002) 2325-2332
9. Lloyd-Jones D.M., Evans J.C., and Levy D. Hypertension in adults across the age spectrum: Current outcomes and control in the community. JAMA 294 (2005) 466-472
10. Primatesta P., and Poulter N.R. Hypertension management and control among English adults aged 65 years and older in 2000 and 2001. J Hypertens 22 (2004) 1093-1098
11. Khan N.A., McAlister F.A., Lewanczuk R.Z., et al., Canadian Hypertension Education Program. The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II-therapy. Can J Cardiol 21 (2005) 657-672
12. Tu K., Campbell N.R., Duong-Hua M., and McAlister F.A. Hypertension management in the elderly has improved: Ontario prescribing trends, 1994 to 2002. Hypertension 45 (2005) 1113-1118
13. International Classification of Diseases, Ninth Revision, Clinical Modification. 6th ed. (2005), US Dept of Health and Human Services, Centers for Disease Control and Prevention, Centers for Medicare and Medicaid Services, Washington, DC
14. Williams J.I., and Young W. A summary of studies on the quality of health care administrative databases in Canada. In: Goel V., Williams J.I., Anderson G.M., et al. (Eds). Patterns of Health Care in Ontario. The ICES Practice Atlas. 2nd ed. (1996), Canadian Medical Association, Ottawa, Ontario, Canada 339-345
15. Hux J.E., Ivis F., Flintoft V., and Bica A. Diabetes in Ontario: Determination of prevalence and incidence using a validated administrative data algorithm. Diabetes Care 25 (2002) 512-516
16. July. Wilkins R. PCCF + Version 4D User's Guide: Automated Geographic Coding Based on the Statistics Canada Postal Code Conversion Files, Including Postal Codes to December 2003 (2004), Health Analysis and Measurement Group, Statistics Canada, Ottawa, Ontario, Canada
17. Mustard C.A., Derksen S., Berthelot J.M., and Wolfson M. Assessing ecologic proxies for household income: A comparison of household and neighbourhood level income measures in the study of population health status. Health Place 5 (1999) 157-171
18. Usher C., Bennett K., and Feely J. Evidence for a gender and age inequality in the prescribing of preventative cardiovascular therapies to the elderly in primary care. Age Ageing 33 (2004) 500-502
19. Pears E., Hannaford P.C., and Taylor M.W. Gender, age and deprivation differences in the primary care management of hypertension in Scotland: A cross-sectional database study. Fam Pract 20 (2003) 22-31
20. Onder G., Gambassi G., Landi F., et al., Investigators of the GIFA Study (SIGG-ONLUS). Trends in antihypertensive drugs in the elderly: The decline of thiazides. J Hum Hypertees 15 (2001) 291-297
21. Medical Research Council Working Party. MRC trial of treatment of mild hypertension: Principal results. BMJ (Clip Res Ed) 291 (1985) 97-104
22. Neaton J.D., Grimm Jr. R.H., Prineas R.J., et al., Treatment of Mild Hypertension Study Research Group. Treatment of Mild Hypertension Study. Final results. JAMA 270 (1993) 713-724
23. Wing L.M., Reid C.M., Ryan P., et al., Second Australian National Blood Pressure Study Group. A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly. N Engl J Med 348 (2003) 583-592
24. [published corrections appear in JAMA. 2003;289:178 and JAMA. 2004;291:2196]. ALLHAT Officers and Coordinators for the ALLRAT Collaborative Research Group. Major outcomes in highrisk hypertensive patients randomized to angiotensin converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLRAT). JAMA 288 (2002) 2981-2997
25. Schoofs M.W., van der Klift M., Hofiman A., et al. Thiazide diuretics and the risk for hip fracture. Ann Intern Med 139 (2003) 476-482
26. Chow K.M., Szeto C.C., Wong T.Y., et al. Risk factors for thiazide-induced hyponatraemia. QJM 96 (2003) 911-917
27. Ahmed A., Allman R.M., DeLong I.F., et al. Age-related underutilization of angiotensin-converting enzyme inhibitors in older hospitalized heart failure patients. South Med J 95 (2002) 703-710
28. Solberg L.I., Brekke M.L., and Kottke T.E. Are physicians less likely to recommend preventive services to low-SES patients?. Prev Med 26 (1997) 350-357
29. Scott A., Shiell A., and King M. Is general practitioner decision making associated with patient socio-economic status?. Soc Sci Med 42 (1996) 35-46
30. McAlister F.A., Murphy N.F., Simpson C.R., et al. Influence of socioeconomic deprivation on the primary care burden and treatment of patients with a diagnosis of heart failure in general practice in Scotland: Population based study. BMJ 328 (2004) 1110
31. Joffres M.R., Ghadirian P., Fodor J.G., et al. Awareness, treatment, and control of hypertension in Canada. Am J Hypertens 10 (1997) 1097-1102
32. [abstract]. Campbell N.R., Onysko J., Maxwell C., et al., Canadian Hypertension Education Program. Increases in the diagnosis and drug treatment of hypertensive Canadians. Montreal, Quebec, Canada. Presented at: 58th Annual Meeting of the Canadian Cardiovascular Society (October 22-26, 2005)