Chronic mountain sickness, optimal hemoglobin and heart disease

High Altitude Medicine and Biology

Volumn 7, Issue 2, 2006, Pages 138-149

  Vargas, Enrique P ^a   Spielvogel, Hilde ^a  

^a UNIVERSIDAD MAYOR DE SAN ANDRÉS   (Bolivia)

Author keywords

Blood viscosity; Congenital; Cor pulmonale; High altitude; Oxygen saturation; Pulmonary hypertension

Indexed keywords

HEMOGLOBIN;

ALTITUDE ACCLIMATIZATION; ALTITUDE DISEASE; ARTICLE; ASIA; BOLIVIA; CALCULATION; CHAGAS DISEASE; CONGENITAL HEART DISEASE; COR PULMONALE; EXPERIENCE; HEART ATRIUM SEPTUM DEFECT; HEART DISEASE; HEART VENTRICLE SEPTUM DEFECT; HEMATOCRIT; HEMOGLOBIN DETERMINATION; HUMAN; HYPOTHESIS; MALE; MEDICAL RESEARCH; PATENT DUCTUS ARTERIOSUS; PATHOGENESIS; PRIORITY JOURNAL; REST; RHEUMATIC HEART DISEASE; SOUTH AMERICA; WESTERN HEMISPHERE;

ACCLIMATIZATION; ALTITUDE; ALTITUDE SICKNESS; ANIMALS; BOLIVIA; CARDIOVASCULAR DISEASES; CHRONIC DISEASE; HEMATOCRIT; HEMOGLOBINS; HUMANS; INDIANS, SOUTH AMERICAN; OXYGEN CONSUMPTION;

EID: 33745948167     PISSN: 15270297     EISSN: None     Source Type: Journal    
DOI: 10.1089/ham.2006.7.138     Document Type: Article

References (51)

1. American Thoracic Society. (1987). Single breath carbon monoxide diffusing capacity (transfer factor). Recommendations for a standard technique. Am. Rev. Respir. Dis. 136:1299-1307.
2. Antezana G., Barragán L., Coudert J., Cudkowicz L., Durand J., Lockhart A., Mensch-Dechene J., Paz Zamora M., Spielvogel H., Vargas E., and Zelter M. (1982). The pulmonary circulation of high altitude natives. In: High Altitude Physiology and Medicine. W. Brendel and R.A. Zink., eds. Springer Verlag, New York; pp. 142-149.
3. Antezana G., Villena C.M., Dávalos F., Calmon P., and Contreras G. (1978). Encuesta cardiovascular en Chorolque. Informe Encuesta en la Población de Chorolque. Edit. Universidad Mayor de San Andrés. La Paz; pp. 73-76.
4. Aparicio O., and Garabito L.R. (1990). Cardiopatías congénitas en adultos nativos de la altura. Estudio retrospectivo sobre incidencia hospitalaria, manifestaciones clínicas y exámenes complementarios. Cuadernos del Hospital de Clínicas 36(2):10-23. La Paz.
5. Aparicio O., Romero F., Harris P., and Anand I. (1991). Echocardiograph shows persistent thickness of the wall of the right ventricle in infants at high altitude. Cardioscience. 2:63-69.
6. Aste Salazar H., and Hurtado A. (1944). The affinity of hemoglobin for oxygen at sea level and high altitudes. Am. J. Physiol. 142(5):733-743.
7. Corone P., Drouet L., Escourrou P., and Antezana G. (1976). Epidemiologie cardio-vasculaire des sujets boliviens residents en haute et basse altitude. Anthropologie des Populationes Andines. INSERM. 63:333-344.
8. Cotes J.E., Debbs J.M., Elwood P.C., Hall A.M., McDonald A., and Saunders M.J. (1972). Iron-deficiency anemia: its effect on transfer factor for the lung (diffusing capacity) and ventilation and cardiac frequency during sub-maximal exercise. Clin. Sci. 42:325-335.
9. Coudert J., Paz Zamora M., Barragán L., Briançón L., Spielvogel H., and Cudkowicz L. (1975). Regional distribution of pulmonary blood flow in normal high altitude dwellers at 3650 m (12,200 ft.). Respiration. 32:189-209.
10. Cudkowicz L., Coudert J., Paz Zamora M., Barragán L., Briançon L., Spielvogel H., Machicao N., and Saldaña M. (1978). The regional distribution of pulmonary blood flow in normal high altitude dwellers at 3650 m. (12,200) and in chronic mountain sickness. In: Selected Topics in Environmental Biology. B. Bhatia, G. S. China, and B. Shing, eds. Interprint Publications, New Delhi; pp. 256-262.
11. Dejours P. (1977). Le Transport de l'oxygene. Monographie de la Société de Réanimation de Langue Française; pp. 9-15.
12. Dejours P. (1963). Respiration Physiologie. Les grands fonctions. Cap.1, 7-246. Edit Kayser.
13. Ergueta J., Spielvogel H., and Cudkowicz L. (1971). Cardio-respiratory studies in chronic mountain sickness (Monge's Syndrome). Respiration 28:485-517.
14. Farfán C. J., Salinas Salmón C., Aparicio O., Vargas P. E., Villena C. M., Gómez J., and Murillo W. (2000). Pulmonary artery pressure, right ventricular wall thickness and EKG, in 6 to 8-year-old children of La Paz-Bolivia (3600 m). Abstract 64, High Alt. Med. Biol. 1:238.
15. Graham B.L., Mink J.T., and Cotton D.J. (1981). Improved accuracy and precision of single-breath CO diffusing measurements. J. Appl. Physiol. 51(5):1306-1313.
16. Guénard H., Vargas E., Villena M., and Carras P.M. (1984). Hypoxémie et hematocrito dans la polyblobulie pathologique d altitude. Bull. Eur. Physioathol. Resp. 20:319-324.
17. Guyton A.C., Jones C.E., and Coleman T.G. (1973). Cardiac Output and Its Regulation, 2nd ed. Saunders, Philadelphia; p. 396.
18. Krogh A., and Leitch I. (1918-1919). The respiratory function of the blood in fishes. J. Physiol. (Lond.) 52:288-300.
19. Lahiri S., Kao F., Velásquez T., Martinez M., and Pezzia W. (1969). Irreversible blunted respiratory sensitivity to hypoxia in high altitude natives. Respir. Physiol. 6:360-374.
20. Lefrançois R., Gautier H., and Pasquis P. (1968). Ventilatory oxygen drive in acute and chronic hypoxia. Respir. Physiol. 4:119-228.
21. Lenfant C., Torrance J.D., and Reynafarje C. (1971). Shift of the O2-Hb dissociation curve at altitude: mechanism and effect. J. Appl. Physiol. 33:625-631.
22. León-Velarde F., Gamboa J., Gamboa A., Rivera-China M., Macarlupu JL., and Monge C. (2003). Domperidone: a possible strategy for chronic mountain sickness therapy. In: Health & Height: Proceedings of the 5th World Congress on Mountain Medicine and High Altitude Physiology, G. Viscor, A. Ricart, and C. Leal, eds. Universitat de Barcelona; pp. 57-65.
23. León-Velarde F., Maggiorini M., Reeves J.T., Aldashev A., Asmas I., Bernardi L., Ge R.-L., Hackett P., Kobayashi T., Moore L.G., Peñaloza D., Richalet J.-P., Roach R., Wu T., Vargas E. Zubieta-Castillo G., and Zubieta-Calleja G. (2005). Consensus Statement on Chronic and Subacute High Altitude Diseases. High Alt. Med. Biol. 6:147-157.
24. Manier G., Guénard H., Castaing Y., Varene N., and Vargas E. (1988). Pulmonary gas exchange in Andean natives with excessive polycythemia - effect of hemodilution. J. Appl. Physiol. 65(5):2107-2117.
25. Monge Medrano C. (1925). Sobre un caso de enfermedad de Vaquez (Síndrome Eritremico de Altura). Comunicación presentada a la Academia Nacional de Medicina. In: Carlos Monge: Obras. Lima, UPCH, 1988. vol. 2: pp. 571-577.
26. Monge-C C., Arregui A., and León-Velarde F. (1992). Pathophysiology and epidemiology of chronic mountain sickness. Int. J. Sports Med. 13(Suppl 1):S579-S581.
27. Monge C., and Whittembury J. (1976). High altitude adaptations in the whole animal. Environmental Physiology of Animals. J. Blight, J.L. Cloused-Thompson, and A.G. MacDonald, eds. New York: Wiley.
28. Monge C., and Whittembury J. (1982). Chronic mountain sickness and the physiopathology of hypoxemic polycythemia. In: Hypoxia: Man at Altitude. J.R. Sutton, N.L. Jones, and C.S. Houston, eds. New York: Thieme and Stratton.
29. Moret-P.R., Covarrubias E., Coudert J., and Duchosal F. (1972). Cardiocirculatory adaptation to chronic hypoxia. Comparative study of coronary flow, myocardial oxygen consumption and efficiency between sea level and high altitude residents. Acta Cardiol. 27(2):283-305.
30. Moulin J. (1971). Hematimetrie et Cytologie en Milieu Tropical de l'Amerique du Sud. Variations Ecologiques et Raciales. These Doctorat Universitéde Toulouse, France.
31. Niermeyer S., Andrade P., Vargas P. E., and Moore L.G. (2002). Prolonged postnatal pulmonary transition at 3700-4000 m. Abstract. High Alt. Med. Biol. 3:439.
32. Niermeyer S., Zamudio S., and Morre L.G. (2001). The people. In: High Altitude. An Exploration of Human Adaptation. T. F. Hornbein and R. B. Schoene, eds. New York: Dekker.
33. Normand H., Vargas E., Bordachar J., Benoit O., and Raynaud J. (1992). Sleep apneas in high altitude residents (3800 m). Int. J. Sports Med. 13:S40-S42.
34. Peñaloza D. (1969). Corazón Pulmonar Crónico por desadaptación a la altura. Tesis Edit. Universidad Peruana Cayetano Heredia.
35. Ponce Caballero G., Loma Rodriguez F., Villegas P. J., and Laura G. M. (1976). Persistencia del conducto arterial hipertenso en la altura. Anthropologie des Populations Andines. INSERM 63:333-344.
36. Reeves J.T., and Weil J.V. (2001). Chronic Mountain Sickness, A View from the Crow's Nest. In Hypoxia: From Genes to the Bedside. R. C. Roach, ed. Kluwer Academic/Plenum Publishers, New York.
37. Salinas Salmón C. (1999). La Cardiopatía Chagasica Crónica. Chagas, la enfermedad en Bolivia. Edit. OPS/OMS; pp. 49-59.
38. Severinghaus J., Bainton C., and Carcelen A. (1966). Respiratory insensitivity to hypoxia in chronically hypoxic man. Respir. Physiology 1:308-314.
39. Tufts D.A., Haas J.D., Beard J.L., and Spielvogel H. (1985). Distribution of hemoglobin and functional consequences of anemia in adult males at high altitude. Am. J. Clin. Nutr. 42:1-11.
40. Vargas E., and Villena M. (1993). Factores predominantes en la etiopatogenia de la enfermedad de Monge (EPA) en La Paz, Bolivia (3.600-4.000 m). In: Hypoxia - Investigaciones Basicas y Clínicas - Homenaje a Carlos Monge Cassinelli. IFEA, UPCH: pp. 263-282.
41. Vargas E., and Villena M. (1989). La vie humaine en haute altitude: mythes et realites. Bull. Soc. Path. Ex. 82:701-719.
42. Vargas E., Villena M., Salinas C., Rodríguez A., Spielvogel H., Téllez W., and Bellido D. (2002). Excessive polycythemia occurs in young high altitude (3600 m) residents in the absence of lung disease. In: Health & Height: Proccedings of the 5th World Congress on Mountain Medicine and High Altitude Physiology. G. Viscor, A. Ricart, and C. Leal, eds. Universitat de Barcelona; pp. 43-48.
43. Vasquez R., and Villena C.M. (2001). Normal hematological values for healthy persons living at 4000 m. in Bolivia. High Alt. Med. Biol. 2:361-367.
44. Villafuerte F.C., Cárdenas R., and Monge C.C. (2004). Optimal hemoglobin concentration and high-altitude a theoretical approach for Andean men at rest. J. Appl. Physiol. 96:1581-1588.
45. Villena M., Vargas E., Guenard H., Nallar N., Tellez W., and Spielvogel H. (1985). Etude en double insu de l'effet de l'almitrine sur les malades porteurs de polyglobulie pathologique d'altitude. Bull. Eur. Physiopathol. Respir. 21:165-170.
46. Ward M.P, Milledge J., and West J. (1989). High Altitude Medicine and Physiology. Haematological Changes and Plasma Volume. Chapman and Hall Medical; 161-177.
47. Weil J.V., Byrne-Quinn E., Social E., Filley G.F., and Grover R.F. (1971). Acquired attenuation of chemoreceptor function in chronically hypoxic men at high altitude. J. Clin. Invest. 50:186-195.
48. Whittembury J., Lozano R., Torrez C., and Monge C. (1968). Blood viscosity in high altitude polycythemia. Acta Physiol. Latinoam. 18:355-359.
49. Winslow R., Monge C., Brown E., Klein H., Sarnquist F., Winslow N., and McNeally S. (1985). Effects of hemodilution on O2 transport in high altitude polycythemia. J. Appl. Physiol 59:1495-1502.
50. Wu T., Li W., Li Y., Ge Re-Li, Cheng Q., Wang S., Zhao G., Wei L., Jin Y., and Don G. (1998). Epidemiology of chronic mountain sickness: ten years study in Qinghai-Tibet. In: Progress in Mountain Medicine and High Altitude Physiology. H. Ohno, T. Kobayashi, S. Mayusama, and M. Nakashima. eds. Matsumoto, Japan; pp. 120-125.
51. Zuazo V.H., Jáuregui T.P., and Ordóñez B.J. (1982). Enfermedad cardiopulmonar crónica en Instituto Nacional del Torax. Gaceta del Torax, Vol 4; pp 29-43.