Lobeline augments and inhibits cocaine-induced hyperactivity in rats

Life Sciences

Volumn 79, Issue 10, 2006, Pages 981-990

  Polston, James E ^a   Cunningham, Colin S ^a   Rodvelt, Kelli R ^a   Miller, Dennis K ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Cocaine; Lobeline; Nicotinic receptor

Indexed keywords

COCAINE; LOBELINE; SODIUM CHLORIDE;

ACUTE DRUG ADMINISTRATION; ADAPTIVE BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL MONITORING; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG SENSITIZATION; HYPERACTIVITY; MALE; NEUROCHEMISTRY; NONHUMAN; RAT; RECEPTOR AFFINITY;

ANIMALS; COCAINE; COCAINE-RELATED DISORDERS; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; LOBELINE; MALE; MOTOR ACTIVITY; PSYCHOMOTOR AGITATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC;

EID: 33745945424     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.05.006     Document Type: Article

References (34)

1. Bechtholt A.J., and Mark G.P. Enhancement of cocaine-seeking behavior by repeated nicotine exposure in rats. Psychopharmacology (Berl) 162 2 (2002) 178-185
2. Brown J.M., Hanson G.R., and Fleckenstein A.E. Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants. Journal of Pharmacology and Experimental Therapeutics 296 3 (2001) 762-767
3. Chen N.-H., and Reith M.E. Structure-function relationships for biogenic amine neurotransmitter transporters. In: Reith M.E. (Ed). Neurotransmitter Transporters: Structure, Function and Regulation (2002), Humana Press, Totowa, NJ 53-109
4. Collins S.L., and Izenwasser S. Chronic nicotine differentially alters cocaine-induced locomotor activity in adolescent vs. adult male and female rats. Neuropharmacology 46 3 (2004) 349-362
5. Cunningham, C.S., Polston, J.E., Jany, J.R., Segert, I.L., Miller, D.K., in press. Interaction of lobeline and nicotinic receptor ligands with the discriminative stimulus properties of cocaine and amphetamine. Drug and Alcohol Dependence.
6. Damaj M.I., Patrick G.S., Creasy K.R., and Martin B.R. Pharmacology of lobeline, a nicotinic receptor ligand. Journal of Pharmacology and Experimental Therapeutics 282 1 (1997) 410-419
7. Damaj M.I., Slemmer J.E., Carroll F.I., and Martin B.R. Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs. Journal of Pharmacology and Experimental Therapeutics 289 3 (1999) 1229-1236
8. Desai R.I., Barber D.J., and Terry P. Dopaminergic and cholinergic involvement in the discriminative stimulus effects of nicotine and cocaine in rats. Psychopharmacology (Berl) 167 4 (2003) 335-343
9. Dwoskin L.P., and Crooks P.A. A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse. Biochemical Pharmacology 63 2 (2002) 89-98
10. Eyerman D.J., and Yamamoto B.K. Lobeline attenuates methamphetamine-induced changes in vesicular monoamine transporter 2 immunoreactivity and monoamine depletions in the striatum. Journal of Pharmacology and Experimental Therapeutics 312 1 (2005) 160-169
11. Flammia D., Dukat M., Damaj M.I., Martin B., and Glennon R.A. Lobeline: structure-affinity investigation of nicotinic acetylcholinergic receptor binding. Journal of Medicinal Chemistry 42 18 (1999) 3726-3731
12. 3H]norepinephrine from fetal rat locus coeruleus cells in culture. Journal of Neurochemistry 70 2 (1998) 663-670
13. Harrod S.B., Dwoskin L.P., Crooks P.A., Klebaur J.E., and Bardo M.T. Lobeline attenuates d-methamphetamine self-administration in rats. Journal of Pharmacology and Experimental Therapeutics 298 1 (2001) 172-179
14. Harrod S.B., Dwoskin L.P., Green T.A., Gehrke B.J., and Bardo M.T. Lobeline does not serve as a reinforcer in rats. Psychopharmacology (Berl) 165 4 (2003) 397-404
15. Horger B.A., Giles M.K., and Schenk S. Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine. Psychopharmacology (Berl) 107 2-3 (1992) 271-276
16. Karler R., Calder L.D., and Bedingfield J.B. A novel nicotinic-cholinergic role in behavioral sensitization to amphetamine-induced stereotypy in mice. Brain Research 725 2 (1996) 192-198
17. Levin E.D., Mead T., Rezvani A.H., Rose J.E., Gallivan C., and Gross R. The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats. Physiology and Behavior 71 5 (2000) 565-570
18. + efflux from thalamic synaptosomes. Neuropharmacology 39 13 (2000) 2654-2662
19. Miller D.K., Crooks P.A., Teng L., Witkin J.M., Munzar P., Goldberg S.R., Acri J.B., and Dwoskin L.P. Lobeline inhibits the neurochemical and behavioral effects of amphetamine. Journal of Pharmacology and Experimental Therapeutics 296 3 (2001) 1023-1034
20. Miller D.K., Harrod S.B., Green T.A., Wong M.Y., Bardo M.T., and Dwoskin L.P. Lobeline attenuates locomotor stimulation induced by repeated nicotine administration in rats. Pharmacology, Biochemistry and Behavior 74 2 (2003) 279-286
21. * nAChRs. Journal of Pharmacology and Experimental Therapeutics 310 (2004) 1035-1045
22. Nation J.R., Livermore C.L., and Bratton G.R. Cadmium exposure attenuates the initiation of behavioral sensitization to cocaine. Brain Research 702 1-2 (1995) 223-232
23. Pierce R.C., and Kalivas P.W. A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants. Brain Research Reviews 25 2 (1997) 192-216
24. Rasmussen T., and Swedberg M.D. Reinforcing effects of nicotinic compounds: intravenous self-administration in drug-naive mice. Pharmacology, Biochemistry and Behavior 60 2 (1998) 567-573
25. Reavill C., Walther B., Stolerman I.P., and Testa B. Behavioural and pharmacokinetic studies on nicotine, cytisine and lobeline. Neuropharmacology 29 7 (1990) 619-624
26. Reith M.E. Effect of repeated administration of various doses of cocaine and WIN 35,065-2 on locomotor behavior of mice. European Journal of Pharmacology 130 1-2 (1986) 65-72
27. Schoffelmeer A.N.M., De Vries T.J., Wardeh G., van de Ven H.W.M., and Vanderschuren L.J.M.J. Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation. Journal of Neuroscience 22 8 (2002) 3269-3276
28. Stolerman I.P., Garcha H.S., and Mirza N.R. Dissociations between the locomotor stimulant and depressant effects of nicotinic agonists in rats. Psychopharmacology (Berl) 117 4 (1995) 430-437
29. 3H]dopamine uptake. Journal of Pharmacology and Experimental Therapeutics 280 3 (1997) 1432-1444
30. 3H]dopamine from rat striatal synaptic vesicles: comparison with d-amphetamine. Journal of Neurochemistry 71 1 (1998) 258-265
31. Uhl G.R., Hall F.S., and Sora I. Cocaine, reward, movement and monoamine transporters. Molecular Psychiatry 7 1 (2002) 21-26
32. Wilhelm C.J., Johnson R.A., Lysko P.G., Eshleman A.J., and Janowsky A. Effects of methamphetamine and lobeline on vesicular monoamine and dopamine transporter-mediated dopamine release in a cotransfected model system. Journal of Pharmacology and Experimental Therapeutics 310 3 (2004) 1142-1151
33. Wise R.A. Drug-activation of brain reward pathways. Drug and Alcohol Dependence 51 1-2 (1998) 13-22
34. Wise R.A., and Bozarth M.A. A psychomotor stimulant theory of addiction. Psychological Review 94 4 (1987) 469-492