A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding.

Science's STKE : signal transduction knowledge environment

Volumn 2006, Issue 341, 2006, Pages

  Arnold, Leggy A ^a   Estébanez Perpiñá, Eva ^a   Togashi, Marie ^a   Shelat, Anang ^a   Ocasio, Cory A ^a   McReynolds, Andrea C ^a   Nguyen, Phuong ^a   Baxter, John D ^a   Fletterick, Robert J ^a   Webb, Paul ^a   Guy, R Kiplin ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; GLUTATHIONE TRANSFERASE; HISTONE ACETYLTRANSFERASE; NUCLEAR RECEPTOR COACTIVATOR 3; THYROID HORMONE RECEPTOR; TRANSACTIVATOR PROTEIN;

ARTICLE; BINDING COMPETITION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; FLUORESCENCE POLARIZATION; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR WEIGHT; OSMOLARITY; PHOTOCHEMISTRY; PROTEIN BINDING; ROTATION; SENSITIVITY AND SPECIFICITY;

ACETYLTRANSFERASES; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE POLARIZATION; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HISTONE ACETYLTRANSFERASES; HUMANS; INDICATORS AND REAGENTS; MOLECULAR WEIGHT; OSMOLAR CONCENTRATION; PHOTOCHEMISTRY; PROTEIN BINDING; RECEPTORS, THYROID HORMONE; ROTATION; SENSITIVITY AND SPECIFICITY; TRANS-ACTIVATORS;

EID: 33745943980     PISSN: None     EISSN: 15258882     Source Type: Journal    
DOI: 10.1126/stke.3412006pl3     Document Type: Article

References (0)