Induction therapy for active lupus nephritis: Mycophenolate mofetil versus cyclophosphamide: Commentary

Nature Clinical Practice Nephrology

Volumn 2, Issue 6, 2006, Pages 314-315

  Burchardi, Christian ^a   Schlöndorff, Detlef ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYCLOPHOSPHAMIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE;

ADULT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DIARRHEA; DISEASE SEVERITY; DRUG EFFICACY; DRUG FATALITY; DRUG SAFETY; FEMALE; HEMATURIA; HUMAN; INFECTION; KIDNEY BIOPSY; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; NOTE; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL; REMISSION; TREATMENT FAILURE; TREATMENT OUTCOME; UNITED STATES; URINE SEDIMENT;

ADMINISTRATION, ORAL; ADULT; CROSS-OVER STUDIES; CYCLOPHOSPHAMIDE; DRUG THERAPY, COMBINATION; FEMALE; GLUCOCORTICOIDS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFUSIONS, INTRAVENOUS; LUPUS NEPHRITIS; MALE; MYCOPHENOLIC ACID; PREDNISONE; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 33745932919     PISSN: 17458323     EISSN: 17458331     Source Type: Journal    
DOI: 10.1038/ncpneph0184     Document Type: Note

References (5)

1. Houssiau FA et al. (2004) Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial. Arthritis Rheum 50: 3934-3940
2. Contreras G et al. (2004) Sequential therapies for proliferative lupus nephritis. N Engl J Med 350: 971-980
3. Chan TM et al. (2005) Long-term study of mycophenolate mofetil as continuous induction and maintenance treatment for diffuse proliferative lupus nephritis. J Am Soc Nephrol 16: 1076-1084
4. Austin HA 3rd et al. (1986) Therapy of lupus nephritis: controlled trial of prednisone and cytotoxic drugs. N Engl J Med 314: 614-619
5. Shaw LM et al. (2000) Pharmacokinetics and concentration-control investigations of mycophenolic acid in adults after transplantation. Ther Drug Monit 22: 14-19