Stochastic model for the spatial visualization of particle-deposition patterns in the lung and their significance in lung medicine;Stochastisches modell zur räumlichen visualisierung von teilchendepositionsmustern in der lunge und ihre bedeutung in der lungenmedizin

Zeitschrift fur Medizinische Physik

Volumn 16, Issue 2, 2006, Pages 140-147

  Sturm, Robert ^a,b   Hofmann, Werner ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

^b NONE   (Austria)

Author keywords

Deposition distribution; Deposition forces; Lung; Stochastic lung model

Indexed keywords

ARTICLE; CALCULATION; COMPUTER MODEL; DIFFUSION; GLYCATION; LUNG; PARTICLE SIZE; SEDIMENTATION; SIMULATION; STOCHASTIC MODEL; THREE DIMENSIONAL IMAGING; TRACHEA;

EID: 33745922887     PISSN: 09393889     EISSN: None     Source Type: Journal    
DOI: 10.1078/0939-3889-00306     Document Type: Article

References (20)

1. Fleming, J.S., Nassim, M., Hashish, A.H., Bailey, A.G., Conway, J., Holgate, S., Maison, P., Moore, E., Marionen, T.B.: Description of pulmonary deposition of radio-labeled aerosol by airway generation using a conceptual three-dimensional model of lung morphology. J. Aerosol Med. 8(1995)341-356
2. Fleming, J.S., Hashish, A.H., Conway, J.H., Nassim, M.A., Holgate, S.T., Halson, P., Moore, E., Bailey, A.G., Marionen, T.B.: Assessment of deposition of inhaled aerosol in the respiratory tract of man using three-dimensional multimodality imaging and mathematical modeling. J. Aerosol Med. 9 (1996) 317-327
3. Fleming, J.S., Conway, J.H., Holgate, ST., Bailey, A.G., Marionen, T.B.: Comparison of methods for deriving aerosol deposition by airway generation from three-dimensional radionuclide imaging. J. Aerosol Sci. 31 (2000) 1251-1259
4. Haefeli-Bleuer, B., Weibel, E.R.: Morphometry of the human pulmonary acinus. Anat. Rec. 220 (1988) 401-414
5. Hofmann, W., Koblinger, L.: Monte Carlo modeling of aerosol deposition in human lungs. Part II: Deposition fractions and their sensitivity to parameter variations. J. Aerosol Sci. 21 (1990) 675-688
6. Hofmann, W., Sturm, R., Asgharian, B.: Stochastic simulation of particle clearance in human bronchial airways. J. Aerosol Sci. 32 (Suppl. 1) (2001) S807-S808
7. Horsfiled, K., Dart, G., Olson, D.E., Filley, G.F., Cumming, G.: Models of the human bronchial tree. J. Appl. Physiol. 31 (1971) 207-217
8. International Commission on Radiological Protection (ICRP): Human respiralory tract model for radiological protection, Publication 66. Pergamon Press. Oxford 1994
9. Koblinger, L., Hofmann, W.: Analysis of human lung morphomelric dala for stochastic aerosol deposition calculations. Phys. Med. Biol. 30 (1985) 541-556
10. Koblinger, L., Hofmann, W.: Monle Carlo modeling of aerosol deposition in human lungs. Part I: Simulation of particle transport in a stochastic lung structure. J. Aerosol Sci. 21 (1990) 661-674
11. Raabe, O.G., Yeh, H.C., Schum, G.M., Phalen, R.F.: Tracheobronchial geometry: Human, dog, rat, hamster - A compilation of selected data from the project respiratory tract deposition models. Report LF-53. Lovelace Foundation. Albuquerque 1976
12. 2 fuel element fabrication. Health Phys. 48 (1993) 29-48
13. Stahlhofen, W.: Human lung clearance following bolus inhalation of radio-aerosols. In: Extrapolation of dosimetric relationships for inhaled particles and gases. Academic Press, Washington DC 1989, pp. 153-166
14. Sturm, R., Hofmann, W., Scheuch, G., Sommerer, K., Svartengren, M., Camner, P.: Particle clearance in human bronchial airways: Comparison of stochastic model predictions with experimental data. Ann. Occ. Hyg. Suppl. 1 (2002) 329-333.
15. Taulbee, D.B., Yu, C.P.: A theory of aerosol deposition in the human respiratory tract. J. Appl. Physiol. 38 (1975) 77-85
16. Wardlaw, A.J.: Asthma. Bios Scientific Publishers. Oxford 1993
17. Weibel, E.R.: Morphometry of the human lung. Academic Press. New York 1963
18. Yeh, H., Schum, G.M.: Models of human lung airways and their application to inhaled particle deposition. Bull. Math. Biol. 42 (1980) 461-480
19. Yu, C.P., Nicolaides, P., Soong, T.T.: Effect of random airway sizes on aerosol deposition. Am. Ind. Hyg. Assoc. J. 40 (1979) 999-1005
20. Zhang, Z., Kleinstreuer, C., Kim, C.S.: Cyclic micron-size particle inhalation and deposition in a triple bifurcation lung airway model. J. Aerosol Sci. 33 (2002) 257-281