A randomized controlled trial of calcium supplementation to increase bone mineral density in children with juvenile rheumatoid arthritis

Arthritis and Rheumatism

Volumn 54, Issue 7, 2006, Pages 2235-2242

  Lovell, Daniel J ^a,g   Glass, David ^a   Ranz, Julie ^a   Kramer, Sandy ^a   Huang, Bin ^a   Sierra, Rosa I ^b   Henderson, Carol J ^c   Passo, Murray ^a   Graham, Brent ^a   Bowyer, Suzanne ^d   Higgins, Gloria ^e   Rennebohm, Robert ^e   Schikler, Kenneth N ^f   Giannini, Edward ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b Mexican Association of Clinical Biochemistry   (Mexico)

^c GOOD SAMARITAN HOSPITAL   (United States)

^d INDIANA UNIVERSITY   (United States)

^e OHIO STATE UNIVERSITY   (United States)

^f University of Louisville School of Medicine   (United States)

^g CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CARBONATE; METHOTREXATE; PLACEBO; TUMS; VITAMIN D;

ADOLESCENT; ADULT; ARTICLE; BODY COMPOSITION; BONE DENSITY; CALCIUM INTAKE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DIET SUPPLEMENTATION; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG DOSE REGIMEN; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; GENDER; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; OSTEOPENIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE;

ADOLESCENT; ARTHRITIS, JUVENILE RHEUMATOID; BODY COMPOSITION; BONE AND BONES; BONE DENSITY; BONE RESORPTION; CALCIUM; CHILD; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; PROSPECTIVE STUDIES; VITAMIN D;

EID: 33745922884     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21956     Document Type: Article

References (26)

1. Glass DN, Giannini EH. Juvenile rheumatoid arthritis as a complex genetic trait [review]. Arthritis Rheum 1999;42:2261-8.
2. Brewer EJ, Giannini EH, Person DA. Juvenile rheumatoid arthritis. 2nd ed. Philadelphia: WB Saunders; 1982. p. 54-9.
3. Pachman LM, Poznanski AK. Juvenile rheumatoid arthritis. In: Koopman WJ, editor. Arthritis and allied conditions. 12th ed. Baltimore: Lippincott Williams & Wilkins; 1993.
4. Pepmueller PH, Cassidy JT, Allen SH, Hillman LS. Bone mineralization and bone mineral metabolism in children with juvenile rheumatoid arthritis. Arthritis Rheum 1996;39:746-57.
5. Henderson CJ, Cawkwell GD, Specker BL, Sierra RI, Wilmott RW, Campaigne BN, et al. Predictors of total body bone mineral density in non-corticosteroid- treated prepubertal children with juvenile rheumatoid arthritis. Arthritis Rheum 1997;40:1967-75.
6. French AR, Mason T, Nelson AM, Crowson CS, O'Fallon WM, Khosla S, et al. Osteopenia in adults with a history of juvenile rheumatoid arthritis: a population based study. J Rheumatol 2002;29:1065-70.
7. Oen K. Long-term outcomes and predictors of outcomes for patients with juvenile idiopathic arthritis [review]. Best Pract Res Clin Rheumatol 2002;16:347-60.
8. Lien G, Flato B, Haugen M, Vinje O, Sorskaar D, Dale K, et al. Frequency of osteopenia in adolescents with early-onset juvenile idiopathic arthritis: a long-term outcome study of one hundred five patients. Arthritis Rheum 2003;48:2214-23.
9. Johnston CC Jr, Miller JZ, Slemenda CW, Reister TK, Hui S, Christian JC, et al. Calcium supplementation and increases in bone mineral density in children. N Engl J Med 1992;327:82-7.
10. Lloyd T, Andon MB, Rollings N, Martel JK, Landis JR, Demers LM, et al. Calcium supplementation and bone mineral density in adolescent girls. JAMA 1993;270:841-4.
11. Chan GM, Hoffman K, McMurry M. Effects of dairy products on bone and body composition in pubertal girls. J Pediatr 1995;126:551-6.
12. Hillman L, Cassidy JT, Johnson L, Lee D, Allen SH. Vitamin D metabolism and bone mineralization in children with juvenile rheumatoid arthritis. J Pediatr 1994;124:910-6.
13. Pereira RM, Falco V, Corrente JE, Chahade WH, Yoshinari NH. Abnormalities in the biochemical markers of bone turnover in children with juvenile chronic arthritis. Clin Exp Rheumatol 1999;17:251-5.
14. Kasapcopur O, Sever L, Tasdan Y, Caliskan S, Arisoy N. Hypercalciuria and hematuria in juvenile rheumatoid arthritis. J Rheumatol 1998;25:993-6.
15. Abrams SA, Lipnick RN, Vieira NE, Stuff JE, Yergey AL. Calcium absorption and metabolism in children with juvenile rheumatoid arthritis assessed using stable isotopes. J Rheumatol 1993;20:1196-200.
16. Steinbrocker O, Traeger CH, Batteman RC. Therapeutic criteria in rheumatoid arthritis. JAMA 1949;140:659-62.
17. Cimaz R. Osteoporosis in childhood rheumatic diseases: prevention and therapy [review]. Best Pract Res Clin Rheumatol 2002;16:397-409.
18. Rooney M, Davies UM, Reeve J, Preece M, Ansell BM, Woo PM. Bone mineral content and bone mineral metabolism: changes after growth hormone treatment in juvenile chronic arthritis. J Rheumatol 2000;27:1073-81.
19. Reed A, Haugen M, Pachman LM, Langman CB. 25-hydroxyvitamin D therapy in children with active juvenile rheumatoid arthritis: short-term effects on serum osteocalcin levels and bone mineral density. J Pediatr 1991;119:657-60.
20. Lepore L, Pennesi M, Barbi E, Pozzi R. Treatment and prevention of osteoporosis in juvenile chronic arthritis with disodium clodronate. Clin Exp Rheumatol 1991;9 Suppl 6:33-5.
21. Warady BD, Lindsley CB, Robinson FG, Lukert BP. Effects of nutritional supplementation on bone mineral status of children with rheumatic diseases receiving corticosteroid therapy. J Rheumatol 1994;21:530-5.
22. Gravallese EM. Bone destruction in arthritis [review]. Ann Rheum Dis 2002;61 Suppl 2:ii84-6.
23. Papanicolaou DA, Wilder RL, Manolagas SC, Chrousos GP. The pathophysiologic roles of interleukin-6 in human disease [review]. Ann Intern Med 1998;128:127-37.
24. Marzo-Ortega H, McGonagle D, Haugeberg G, Green MJ, Stewart SP, Emery P. Bone mineral density improvement in spondyloarthropathy after treatment with etanercept. Ann Rheum Dis 2003;62:1020-1.
25. Hermann J, Mueller T, Fahrleitner A, Dimai HP. Early onset and effective inhibition of bone resorption in patients with rheumatoid arthritis treated with the tumor necrosis factor α antibody infliximab. Clin Exp Rheumatol 2003;21:473-6.
26. Antoni C, Kavanaugh A, Krueger GG, Guzzo C, Wagner C, Buetler A, et al. Evidence for infliximab-induced improvement of bone metabolism in psoriatic arthritis. Arthritis Rheum 2004;50: S214-5.