Demonstration of a trigeminothalamic pathway to the oval paracentral intralaminar thalamic nucleus and its involvement in the processing of noxious orofacial deep inputs

Brain Research

Volumn 1097, Issue 1, 2006, Pages 116-122

  Sugiyo, Shinichi ^a   Takemura, Motohide ^b   Dubner, Ronald ^a   Ren, Ke ^a  

^a Dental School   (United States)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Fluorogold; Fos; Freund's adjuvant; Orofacial pain; Oval paracentral nucleus; Spinal trigeminal nucleus

Indexed keywords

PROTEIN FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL POPULATION; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MASSETER MUSCLE; NERVE CELL; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; THALAMUS; THALAMUS NUCLEUS; TRIGEMINAL NERVE;

ANIMALS; FACIAL PAIN; INTRALAMINAR THALAMIC NUCLEI; MALE; NEURAL PATHWAYS; RATS; RATS, SPRAGUE-DAWLEY; THALAMIC NUCLEI; TRIGEMINAL NUCLEI;

EID: 33745915565     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.04.079     Document Type: Article

References (16)

1. Berendse H.W., and Groenewegen H.J. Restricted cortical termination fields of the midline and intralaminar thalamic nuclei in the rat. Neuroscience 42 (1991) 73-102
2. Dostrovsky J.O., and Guilbaud G. Nociceptive responses in medial thalamus of the normal and arthritic rat. Pain 40 (1990) 93-104
3. Ikeda T., Terayama R., Jue S.S., Sugiyo S., Dubner R., and Ren K. Differential rostral projections of caudal brainstem neurons receiving trigeminal input after masseter inflammation. J. Comp. Neurol. 465 (2003) 220-233
4. Imbe H., Dubner R., and Ren K. Masseteric inflammation-induced Fos protein expression in the trigeminal interpolaris/caudalis transition zone: contribution of somatosensory-vagal-adrenal integration. Brain Res. 845 (1999) 165-175
5. Jones E.G., and Leavitt R.Y. Retrograde axonal transport and the demonstration of non-specific projections to the cerebral cortex and striatum from thalamic intralaminar nuclei in the rat, cat and monkey. J. Comp. Neurol. 154 (1974) 349-377
6. Krout K.E., Belzer R.E., and Loewy A.D. Brainstem projections to midline and intralaminar thalamic nuclei of the rat. J. Comp. Neurol. 448 (2002) 53-101
7. Kruger L., Saporta S., and Swanson L.W. Photographic Atlas of the Rat Brain (1995), Cambridge Univ. Press, Cambridge, UK
8. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 5th ed. (2005), Elsevier, Amsterdam
9. Ren K. The medulla oblongata: the vital center for descending modulation. J. Pain 3 (2002) 355-357 (discussion 358-359)
10. Rinaldi P.C., Young R.F., Albe-Fessard D., and Chodakiewitz J. Spontaneous neuronal hyperactivity in the medial and intralaminar thalamic nuclei of patients with deafferentation pain. J. Neurosurg. 74 (1991) 415-421
11. Sewards T.V., and Sewards M.A. The medial pain system: neural representations of the motivational aspect of pain. Brain Res. Bull. 59 (2002) 163-180
12. Sewards T.V., and Sewards M.A. Representations of motivational drives in mesial cortex, medial thalamus, hypothalamus and midbrain. Brain Res. Bull. 61 (2003) 25-49
13. Shigenaga Y., Sera M., Nishimori T., Suemune S., Nishimura M., Yoshida A., and Tsuru K. The central projection of masticatory afferent fibers to the trigeminal sensory nuclear complex and upper cervical spinal cord. J. Comp. Neurol. 268 (1988) 489-507
14. Sugiyo S., Takemura M., Dubner R., and Ren K. Trigeminal transition zone/rostral ventromedial medulla connections and facilitation of orofacial hyperalgesia after masseter inflammation in rats. J. Comp. Neurol. 493 (2005) 510-523
15. Tavares I., and Lima D. The caudal ventrolateral medulla as an important inhibitory modulator of pain transmission in the spinal cord. J. Pain 3 (2002) 337-346
16. Weigel R., and Krauss J.K. Center median-parafascicular complex and pain control. Review from a neurosurgical perspective. Stereotact. Funct. Neurosurg. 82 (2004) 115-126