Single-dose actinomycin D: Efficacy in the prophylaxis of postmolar gestational trophoblastic neoplasia in adolescents with high-risk hydatidiform mole

Gynecologic Oncology

Volumn 102, Issue 2, 2006, Pages 325-332

  Uberti, E M H ^a,b   Diestel, M C F ^a,b   Guimaraes F E ^a,b   De Napoli G ^a,b   Schmid, H ^a,b  

^a Centro de Doenças Trofoblásticas TDC   (Brazil)

^b Fundação Faculdade Federal de Ciências Médicas de Porto Alegre   (Brazil)

Author keywords

Actinomycin D; Adolescents; High risk complete hydatidiform mole; Prophylactic chemotherapy

Indexed keywords

DACTINOMYCIN;

ADOLESCENT; ARTICLE; BRAZIL; CANCER CHEMOTHERAPY; CANCER RISK; CLINICAL ARTICLE; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DRUG EFFICACY; EPIGASTRIC PAIN; FEMALE; FOLLOW UP; GESTATION PERIOD; HAIR LOSS; HIGH RISK POPULATION; HOSPITAL DISCHARGE; HUMAN; HYDATIDIFORM MOLE; LIVER TOXICITY; MORBIDITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; REPRODUCTION; RISK FACTOR; RISK REDUCTION; SINGLE DRUG DOSE; STATISTICAL ANALYSIS; TROPHOBLASTIC TUMOR; UTERUS;

ADOLESCENT; ADULT; ANTIBIOTICS, ANTINEOPLASTIC; COHORT STUDIES; DACTINOMYCIN; FEMALE; FOLLOW-UP STUDIES; GESTATIONAL TROPHOBLASTIC NEOPLASMS; HUMANS; HYDATIDIFORM MOLE; PREGNANCY; REPRODUCTION; RETROSPECTIVE STUDIES;

EID: 33745912278     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2005.12.036     Document Type: Article

References (51)

1. Seckl M.J., and Newlands E.S. Management of gestational trophoblastic disease. In: Gershewson D., et al. (Ed). Gynecologic cancer controversies in management. 1st ed. (2004), Elsevier 555-573
2. Newlands E.S., Paradinas F.J., and Fisher R.A. Recent advances in gestational trophoblastic disease. Hematol./Oncol. Clin. North Am. 13 1 (1999) 225-244
3. In: Benirschke K., and Kaufmann P. (Eds). Pathology of the human placenta. 3rd ed. (1995), Springer-Verlag, New York 653-708
4. Bandy L.C., Clarke-Pearson D.L., and Hammond C.B. Malignant potential of gestational trophoblastic disease at the extreme ages of reproductive life. Obstet. Gynecol. 64 (1984) 395-399
5. In: Cunningham F.G., MacDonald P.C., Gant N.F., et al. (Eds). Williams obstetrics. 20th ed. (1997), Appleton and Lange, Norwalk 569-572
6. Bayatpour M., and Reyes J. Gestational trophoblastic disease among adolescents. Adolesc. Ped. Gynecol. 6 (1993) 220-223
7. Uberti E.M.H., Diestel M.C.F., Guimarães F.E., Goloubkova T., Rosa M.W., and de Nápoli G. Gestational trophoblastic disease: one more risk in adolescent pregnancy. Acta Obstet. Gynecol. Scand. 81 (2002) 356-363
8. Altieri A., Franceschi S., Ferlay J., Smith J., and La Vecchia C. Epidemiology and aetiology of gestational trophoblastic diseases. Lancet Oncol. 4 11 (2003) 670-767
9. Kohorn E.I. Single-agent chemotherapy for nonmetastatic gestational trophoblastic neoplasia-perspectives for the 21st century after three decades of use. J. Reprod. Med. 36 (1991) 49-55
10. Hogg M., Knapp J.E., and Lappa C. Psychological and emotional impact on patients and families with gestational trophoblastic disease. J. Reprod. Med. 36 (1991) 166-178
11. Engelhard I.M. Miscarriage as a traumatic event. Clin. Obstet. Gynecol. 47 3 (2004) 547-551
12. Wenzel L.B., Berkowitz R.S., Robinson S., Goldstein D.P., and Bernstein M. Psychological, social and sexual effects of gestational trophoblastic disease on patients and their partners. J. Reprod. Med. 39 (1994) 163-167
13. Lewis Jr. J., Gore H., Hertig A.T., and Goss D.A. Treatment of trophoblastic disease with rationale for the use of adjunctive chemotherapy at the time of indicated operation. Am. J. Obstet. Gynecol. 96 (1966) 710-718
14. Goldstein D.P. Prevention of gestational trophoblastic disease by the use of actinomycin D in molar pregnancies. Obstet. Gynecol. 43 (1974) 475-479
15. Kim D.S., Moon H., Kim K.T., Moon Y.J., and Hwang Y.Y. Effects of prophylactic chemotherapy for persistent trophoblastic disease in patients with complete hydatidiform mole. Obstet. Gynecol. 67 (1986) 690-694
16. Kashimura Y., Kashimura M., Sugimori H., Tsukamoto N., Matsuyama T., Matsukuma K., et al. Prophylactic chemotherapy for hydatidiform mole: five to 15 years follow-up. Cancer 58 (1986) 624-629
17. Berkowitz R.S., Goldstein D.P., Dubeshter B., and Bernstein M. Management of complete molar pregnancy. J. Reprod. Med. 32 (1987) 634-639
18. Ayhan A., Ergeneli M.H., Yüce K., Yapar E.G., and Kisnisci A.H. Effects of prophylatic chemotherapy for postmolar trophoblastic disease in patients with complete hydatidiform mole. Int. J. Gynecol. Obstet. 32 (1990) 39-41
19. Goldstein D.P., and Berkowitz R.S. Prophylactic chemotherapy of complete molar pregnancy. Semin. Oncol. 22 2 (1995) 157-160
20. Limpongsanurak S. Prophylactic actinomycin D for high-risk complete hydatidiform mole. J. Reprod. Med. 46 2 (2001) 110-116
21. Paradinas F.J. The diagnosis and prognosis of molar pregnancy: the experience of the National Referral Center in London. Int. J. Gynecol. Obstet. 60 suppl 1 (1998) S57-S64
22. Hancock B.W. Differences in management and treatment: a critical appraisal. In: Hancock B.W., Newlands E.S., Berkowitz R.S., and Cole L.A. (Eds). Gestational trophoblastic disease. 2nd ed. (2003). http://www.isstd.org Available in: www.isstd.org. Access in: 01 Sept 2003
23. American College of Obstetrics and Gynecology. Diagnosis and treatment of gestational trophoblastic disease. Obstet. Gynecol. 103 6 (2004) 1365-1377
24. Berkowitz R.S., and Goldstein D.P. Presentation and management of persistent gestational trophoblastic disease and gestational trophoblastic tumors in the USA. In: Hancock B.W., Newlands E.S., Berkowitz R.S., and Cole L.A. (Eds). Gestational trophoblastic disease. 2nd ed. (2003). http://www.isstd.org Available in: www.isstd.org. Access in: 01 Sept. 2003
25. Kendall A., Gillmore R., and Newlands E. Chemotherapy for trophoblastic disease: current standards. Curr. Opin. Obstet. Gynecol. 14 (2002) 33-38
26. Lurain J.R. Pharmacotherapy of gestational trophoblastic disease. Expert Opin. Pharmacother. 4 11 (2003) 2005-2017
27. Petrilli E.S., Twiggs L.B., Blessing J.A., Teng N.N.H., and Curry S. Single-dose actinomycin D treatment for nonmetastatic gestational trophoblastic disease. Cancer 60 (1987) 2173-2176
28. Soper J.T., Lewis Jr. J.L., and Hammond C.B. Gestational trophoblastic disease. In: Hoskins W.J., Perez C.A., and Young R.C. (Eds). Principles and practice of gynecology oncology. 2nd ed. (1997), Lippincott-Raven Publishers, Philadelphia 1039-1077
29. Belfort P. As síndromes da Mola Hidatiforme. GO atual 1 (1992) 20-35
30. Lurain J.R., Brewer J.I., Mazur M.T., and Torok E.E. Fatal gestational trophoblastic disease: an analysis of treatment failures. Am. J. Obstet. Gynecol. 144 (1982) 391-395
31. Tsakok F.H.M., Koh S., Ilancheran A., Poh W.K., and Ratnam S.S. Maternal death associated with hydatidiform molar pregnancy. Int. J. Gynaecol. Obstet. 21 (1983) 485-490
32. Schorge J.O., Lea J.S., Farrar D.F., et al. Management of low-risk gestational trophoblastic neoplasia in indigent women. J. Reprod. Med. 48 10 (2003) 780-784
33. Sivanesaratnam V. Management of gestational trophoblastic disease in developing countries. Best Pract. Res. Clin. Obstet. Gynaecol. 17 6 (2003) 925-942
34. Allen J.E., King M.R., Farrar D.F., Miller D.S., and Schorge J.O. Postmolar surveillance at a trophoblastic disease center that serves indigent women. Am. J. Obstet. Gynecol. 188 5 (2003) 1151-1153
35. Moodley M., Tunkyi K., and Moodley J. Gestational trophoblastic syndrome: an audit of 112 patients. A South African experience. Int. J. Gynecol. Cancer 13 (2003) 234-239
36. Slocumb J.C., and Lund C.J. Incidence of trophoblastic disease-increased rate in the youngest age group. Am. J. Obstet. Gynecol. 104 (1969) 421-424
37. McArney E.R., and Hendee W.R. Adolescent pregnancy and its consequences. JAMA 262 1 (1989) 74-77
38. Polaneczky M., and O'Connor K. Pregnancy in adolescence: screening, diagnosis and social assistance. Clin. Pediatr. North Am. 46 1 (1999) 653-674
39. McNeish I.A., Strickland S., Holden L., Rustin G.J.S., Foskett M., Seckl M., et al. Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000. J. Clin. Oncol. 20 (2002) 1838-1844
40. Smith D.B., Newlands E.S., Spruyt O.W., Begent R.H.J., Rustin G.J.S., Mellor B., et al. Ondansetron plus dexamethasone: effective anti-emetic prophylaxis for patients receiving cytotoxic chemotherapy. Br. J. Cancer 61 (1990) 323-324
41. Hartenbach E.M., Saltzman A.K., Carter J.R., and Twiggs L.B. A novel strategy using G-CSF to support EMA/CO for high-risk gestational trophoblastic disease. Gynecol. Oncol. 56 (1995) 105-108
42. Uberti E.M.H., Diestel M.C.F., Lübbe L.P., Zubaran G.M., and Costa P.L. Controle ambulatorial pós-molar: importância da motivação continuada e do atencimento personalizado na adesão da paciente ao tratamento. RBGO 6 (1992) 267-271
43. Diestel M.C.F., Uberti E.M.H., Lacerda M.E., Spagnol L.O., and Silva I.L. Aspectos psicossociais da Doença Trofoblástica Gestacional: importância dos "grupos de ajuda". Acta Oncol. Bras. 21 1 (2001) 183-186
44. Newlands E.S. Investigation and treatment of patients with persistent gestational disease and gestational trophoblastic tumours in the United Kingdom. In: Hancock B.W., Newlands E.S., Berkowitz R.S., and Cole L.A. (Eds). Gestational trophoblastic disease. 2nd ed. (2003). http://www.isstd.org Available in:. www.isstd.org. Access in: 01 Sept. 2003
45. Organização Mundial da Saúde. Série de informes técnicos. Enfermedades Trofoblasticas de la gestación vol. 692 (1983) 7-92
46. Uberti E.M.H., Diestel M.C.F., Conter S.L., and Costa P.L. Estudo comparativo entre duas formas de administração de metotrexato em Neoplasia Trofoblástica Gestacional do Estádio I. Acta Oncol. Bras. 14 1 (1994) 26-30
47. Bagshawe K.D. Choriocarcinoma: a model for tumour markers. Acta Oncol. 31 (1992) 99-106
48. RCOG. The role of hCG in reproductive medicine. BJOG 111 (2004) 1218-1228
49. Berkowitz RS. Answer to inquiry about inexistence of references for Act-D bolus dose. E-mail message. Nov 8, 2004.
50. IBGE. Instituto Brasileiro de Geografia e Estatística. Indicadores sociais brasileiros. 2000.
51. Curry S.L., Hammond C.B., Tyrey L., Creasman W.T., and Parker R.T. Hydatidiform mole: diagnosis, management and long-term follow-up of 347 patients. Obstet. Gynecol. 45 1 (1975) 1-8