Cognitive neuroscience of delusions in aging

Neuropsychiatric Disease and Treatment

Volumn 2, Issue 2, 2006, Pages 181-189

  Holt, Anna E M ^a   Albert, Martin L ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Cognitive neuroscience; Delusions; Dementia

Indexed keywords

NEUROLEPTIC AGENT;

AGED; AGING; CLINICAL FEATURE; COGNITIVE DEFECT; DELUSION; DELUSIONAL MISIDENTIFICATION; DISEASE CLASSIFICATION; ELECTROCONVULSIVE THERAPY; EROTOMANIA; FRONTAL LOBE; GRANDIOSE DELUSION; HUMAN; LEFT HEMISPHERE; NEUROANATOMY; NEUROIMAGING; NEUROSCIENCE; PERSECUTORY DELUSION; PHENOTYPE; PREVALENCE; PSYCHOSIS; REVIEW; RIGHT HEMISPHERE; RISK FACTOR; TEMPORAL LOBE; THOUGHT DISORDER;

EID: 33745904131     PISSN: 11766328     EISSN: None     Source Type: Journal    
DOI: 10.2147/nedt.2006.2.2.181     Document Type: Review

References (80)

1. Alici-Evcimen Y, Ertan T, Eker E. 2003. Case series with late-onset psychosis hospitalized in a geriatric psychiatry unit in Turkey: experience in 9 years. Int Psychogeriatr, 15:69-72.
2. Almeida OP, Howard RJ, Levy R, et al. 1995. Clinical and cognitive diversity of psychotic states arising in late life (late paraphrenia). Psychol Med, 25:699-714.
3. [APA] American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR, 4th ed. Washington DC: APA.
4. Ballard C, Bannister C, Graham C, et al. 1995a. Associations of psychotic symptoms in dementia sufferers. Br J Psychiatry, 167:537-40.
5. Ballard CG, Bannister CL, Patel A, et. al. 1995b. Classification of psychotic symptoms in dementia sufferers. Acta Psychiatr Scand, 92:63-8.
6. Ballard C, Holmes C, McKeith I, et al. 1999. Psychiatry morbidity in dementia with Lewy bodies:a prospective clinical and neuropathological comparative study with Alzheimer's disease. Am J Psychiatry, 156:1039-45.
7. Bassiony MM, Lyketsos CG. 2003.Delusions and hallucinations in Alzheimer's disease:a review of the brain decade. Psychosomatics, 44:388-401.
8. Bassiony MM, Steinberg MS, Warren A, et al. 2000. Delusions and hallucinations in Alzheimer's disease:prevalence and clinical correlates. Int J Geriatr Psychiatry, 15:99-107.
9. Bianchetti A. Binetti G, Zanetti O, Frisoni, et. al. 1992. Delusions in multi-infarct dementia and in Alzheimer's disease. Third International Conference on Alzhemier's disease. 1992 July 12-17; Abano Terme, Italy. Neurobiol Aging, 13(Suppl 1):S9.
10. Binchetti G, Bianchetti A, Padovani A, et. al. 1993. Delusions in Alzheimer's disease and multi-infarct dementia. Acta Neurol Scand, 88:5-9.
11. Binetti G, Padovani A, Magni E, et al. 1995. Delusions in dementia:clinical and CT correlates. Acta Neurol Scand, 91:271-5.
12. Breen N, Caine D, Coltheart M. 2001. Mirrored-self misidentification:two cases of focal onset dementia. Neurocase, 7:239-54.
13. Brune M, Shroder SG. 2003. Erotomania variants in dementia. J Geriatr Psychiatry Neurol, 16:232-4.
14. Burns A, Jacoby R, Levy R. 1990. Psychiatric phenomena in Alzheimer's disease I:disorders of thought content. Br J Psychiatry, 157:72-6.
15. Cloud, G, Carew T, Rothenberg H, et al. 1996. A case of late-onset psychosis:integrating neuropsychological and SPECT data. J Geriatr Psychiatry Neurol, 9:146-53.
16. Cohen D, Eisdorfer C, Gorelick P, et al. 1993. Sex differences in the psychiatric manifestations of Alzheimer's disease. J Am Geriatr Soc, 41:229-32.
17. Cohen-Mansfield J, Taylor L, Werner P. 1998. Delusions and hallucinations in an adult day care population:a longitudinal study. Am J Geriatr Psychiatry, 6:104-21.
18. Cook SE, Miyahara S, Bacanu SA, et. al. 2003. Psychotic symptoms in Alzheimer disease:evidence for subtypes. Am J Geriatr Psychiatry, 11(4):406-413.
19. Corey-Bloom J, Jernigan T, Archibald S, et al. 1995. Quantitative magnetic resonance imaging of the brain in late-life schizophrenia. Am J Psychiatry, 152:447-9.
20. Devanand DP, Brockington CD, Moody BJ, et al. 1992. Behavioral syndromes in Alzheimer's disease. Int Psychogeriatr, 4(Suppl 2): 161-84.
21. Diesfeldt HFA, Troost D. 1995. Delusional misidentification and subsequent dementia:a clinical and neuropathological study. Dementia, 6:94-98.
22. Edelstyna, NMJ, Oyebodeb F, Barrettc K. 2001. The delusions of capgras and intermetamorphosis in a patient with right-hemisphere white-matter pathology. Psychopathology, 34:299-304.
23. Elie M, Primeau F, Cole MG. 1996. Chronic subdural hematoma in the elderly:a case report. J Geriatr Psychiatry Neurol, 9:100-1.
24. Malloy PF, Richardson ED. 1994. The frontal-lobes and content-specific delusions. J Neuropsychiatr, 6:455-66.
25. Fischer C, Bozanovic-Sosic R, Norris M. Review of delusions in dementia. 2004. Am J Alzheimers Dis Other Demen, 19:19-23.
26. Forstl H, Burns A, Jacoby R, et al. 1991. Neuroanatomical correlates of clinical misidentification and misperception in senile dementia of the Alzheimer's type. J Clin Psychiatry, 52:268-71.
27. Forstl H, Besthorn C, Burns A, et al. 1994b. Delusional misidentification in Alzheimer's disease:a summary of clinical and biological aspects. Psychopathology, 27:194-9.
28. Forstl H, Burns A, Levy R, et al. 1994a. Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease. Br J Psychiatry, 165:53-9.
29. Forstl H, Dalgalarrondo P, Riecher-Rossler A, et al. 1994c. Organic factors and the clinical features of late paranoid psychosis:a comparison with Alzheimer's disease and normal aging. Acta Psychiatr Scand, 89: 335-40.
30. Fuchs, T. 1994. Uprooting and late-life psychosis. Eur Arch Psychiatry Clin Neurosci, 244:126-30.
31. Fukuhara R, Ikeda M, Nebu A, et al. 2001. Alteration of rCBF in Alzheimer's disease patients with delusions of theft. Neurorep, 12:2473-6.
32. Geroldi C, Akkawi NM, Galluzzi S, et al. 2000. Temporal lobe asymmetry in patients with Alzheimer's disease with delusions. J Neurol Neurosurg Psychiatry, 69:187-91.
33. Geroldi C, Bresciani L, Zanetti O, et al. 2002. Regional brain atrophy in patients with mild Alzheimer's disease and delusions. Int Psychogeriatr, 14:365-78.
34. Gurian BS, Wexler D, Baker EH. 1992. Late-life paranoia:possible association with early trauma and infertility. Int J Geriatr Psychiatry, 7:277-84.
35. Hafner H, Loffler W, Riecher-Rossler A, et. al. 2001. Schizophrenia and delusions in middle aged and elderly patients. Epidemiology and etiological hypothesis. Nervenarzt, 72:347-57.
36. Harwood DG, Barker WW, Ownby RL, et al. 1999. Prevalence and correlates of Capgras syndrome in Alzheimer's disease. Int J Geriatr Psychiatry, 14:415-20.
37. Haupt M, Romero B, Kurz A. 1996. Delusions and hallucinations in Alzheimer's disease:results from atwo year longitudinal study. Geriatr Psychiatry, 11:965-72.
38. Henderson AS, Kay DW. 1997. The epidemiology of functional psychoses of late onset. Eur Arch Psychiatry Clin Neurosci, 247:176-89.
39. Henderson AS, Korten AE, Levings C, et. al. 1998. Psychotic symptoms in the elderly:aprospective study in a population sample. Int J Geriatr Psychiatry, 13:484-92.
40. Herlitz A, Forsell Y. 1996. Episodic memory deficit in elderly adults with suspected delusional disorder. Acta Psychiatr Scand, 93:355-61.
41. Hirono N, Mori E, Ishii K, et al. 1998. Alteration of regional cerebral glucose utilization with delusions in Alzheimer's disease. J Neuropsychiatr, 10:433-9.
42. Howard R, Almeida O, Levy R. 1994. Phenomenology, demography and diagnosis in late paraphrenia. Psychol Med, 24:397-410.
43. Howard RJ, Forstl H, Almeida O, et al. 1992a. Computer-assisted CT measurements in late paraphrenics with and without Schneiderian first-rank symptoms. Int J Geriatr Psychiatry, 7:35-8.
44. Howard RJ, Forstl H, Burns A, et al. 1992b. First-rank symptoms of Schneider in late paraphrenia:Cortical structural correlates. Br J Psychiatry, 160:108-9.
45. Howard R, Mellers J, Petty R, et al. 1995. Magnetic resonance imaging volumetric measurements of the superior temporal gyrus, hippocampus, parahippocampal gyrus, frontal and temporal lobes in late paraphrenia. Psychol Med, 25:495-503.
46. Hwang JP, Cheng-Hong Y, Shih-Jen Tsai, et al. 1997. Delusions of theft in dementia of the Alzheimer type:a preliminary report. Alzheimer Dis Assoc Disor, 11:110-12.
47. Hwang JP, Chen-Hong Y, Shih-Jen T. 2003. Phantom boarder symptom in dementia. Int J Geriatr Psychiatry, 18:417-20.
48. Hwang JP, Tsai SJ, Yang Ch, et. al. 1999. Persecutory Delusions in Dementia. J Clin Psychiatry, 60:550-3.
49. Idiaquez J, Sandoval E, Seguel A. 2002. Association between neuropsychiatric and autonomic dysfunction in Alzheimer's Disease. Clin Auton Res, 12:43-6.
50. Ikeda M, Shigenobu K, Fukuhara R, et. al. 2003. Delusions of Japanese patients with Alzheimer's disease. Int J Geriatr Psychiatry, 18: 527-32.
51. Jenkins MA, Cimino C, Malloy PF, et al. 1997. Neuropsychiatric factors in the illusion of visitors among geriatric patients:a case series. J Geriatr Psychiatry Neurol, 10:79-87.
52. Jeste DV, Wragg RE, Salmon DP, et al. 1992. Cognitive deficits of patients with Alzheimer's disease with and without delusions. Am J Psychiatry, 149:184-9.
53. Kay DW, Henderson AS, Scott R, et al. 1985. Dementia and depression among the elderly living in the Hobart community:the effect of the diagnostic criteria on the prevalence rates. Psychol Med, 15:771-8.
54. Konakanchi R, Grace JJ, Yap D, et al. 1999. Pimozide in the treatment of litigious delusions. Psychiatr Serv, 50:837.
55. Kotrla KJ, Chacko RC, Harper RG, et al. 1995. SPECT findings on psychosis in Alzheimer's disease. Am J Psychiatry, 152:1470-5.
56. Leroi I, Voulgari A, Breitner JCS, et al. 2003. The epidemiology of psychosis in dementia. Am J Geriatr Psychiatry, 11:83-91.
57. Livingston G, Kitchen G, Manela M, et al. 2001. Persecutory symptoms and perceptual disturbance in a community sample of older people:the Islington study. Int J Geriatr Psychiatry, 16:462-8.
58. Lopez OL, Smith G, Becker JT, et al. 2001. The psychotic phenomenon in probable Alzheimer's disease:a positron emission tomography study. J Neuropsychiatry Clin Neurosci, 13(1):50-55.
59. McKhann G, Drachman D, Folstein M, et al. 1994. Clinical Diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of Health and Human Services Task Force on Alzheimer's dDisease. Neurology, 34:939-44.
60. Malloy PF. 1994. The frontal lobes and content specific delusions. J Neuropsychiatry Clin Neurosci, 6:455-66.
61. Mega MS, Lee L, Dinov ID, et al. 2000. Cerebral correlates of psychotic symptoms in Alzheimer's disease. Neuropsychiatry Neuropsychol Behav Neurol, 13:163-70.
62. Mendez MF, Martin RJ, Smyth KA, et al. 1992. Disturbances of person identification in Alzheimer's disease:a retrospective study. J Nerv Ment Dis, 180:94-6.
63. Mentis MJ, Weinstein EA, Horwitz B, et al. 1996. Abnormal glucose metabolism in the delusional misidentification syndromes:a positron emission tomography study in Alzheimer's disease. Biol Psychiatry, 58:438-49.
64. Ostling S, Johansson B, Skoog I. 2004. Cognitive test performance in relation to psychotic symptoms and paranoid ideation in non-demented 85-year-olds. Psychol Med, 34:443-50.
65. Ostling S, Skoog I. 2002. Psychotic symptoms and paranoid ideation in a nondemented population-based sample of the very old. Arch Gen Psychiatry, 59:53-9.
66. Ota M, Mizukami K, Katano T, et al. 2003. A case of delusional disorder, somatic type with remarkable improvement of clinical symptoms and single photon emission computed tomography findings following modified electroconvulsive therapy. Prog Neuropsychopharmacol Biol Psychiatry, 27:881-4.
67. Rabins PV, Lavrisha M. 2003. Long-term follow-up and phenomenologic differences distinguish among late-onset schizophrenia, late-life depression and progressive dementia. Am J Geriatr Psychiatry, 11:589-94.
68. Rao V, Lyketsos CG. 1998. Delusions in Alzheimer's disease:a review. J Neuropsychiatr, 10:373-82.
69. Schlimme J, Bruggemann B, Haltenhof H, et al. 2002. Paranoia with late onset:psychopathology and psychodynamics. Nervenarzt, 73:289-92.
70. Shinosaki K, Nishikawa T, Takeda M. 2000. Neurobiological basis of behavioral and psychological symptoms in dementia of the Alzheimer type. Psychiatry Clin Neurosci, 54:611-20.
71. Staff RT, Shanks MF, Macintosh L, et al. 1999. Delusions and Alzheimer's disease:SPECT evidence of right hemisphere dysfunction. Cortex, 35:549-60.
72. Staff RT, Venneri A, Gemmell HG, et al. 2000. HMPAO SPECT imaging of Alzheimer's disease patients with similar content-specific autobiographical delusion:comparison using statistical parametric mapping. J Nucl Med, 41:1451-55.
73. Starkenstein SE, Vazquez S, Petracca G, et al. 1994. A SPECT study of delusions in Alzheimer's disease. Neurology, 44:2055-9.
74. Steele C, Rovner B, Chase GA. 1990. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry, 147:1049-51.
75. Sultzer DL, Brown CV, Mandelkern MA, et al. 2003. Delusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer's disease. Am J Psychiatry, 160:341-9.
76. Targum SD, Abbott JL. 1999. Psychoses in the elderly:a spectrum of disorders. J Clin Psychiatry, 60(Suppl 8):4-10.
77. Tsai SJ, Hwang JP, Chen-Hong Y, et al. 1997. Delusional jealousy in dementia. J Clini Psychiatry, 58:492-4.
78. Venneri A, Shanks MF, Staff RT, et al. 2000. Nurturing syndrome:a form of pathological bereavement with delusions in Alzheimer's disease. Neuropsychologia, 38:213-24.
79. Webster J, and Grossberg GT. 1998. Late-life onset of psychotic symptoms. Am J Geriatr Psychiatry, 6:196-202.
80. [WHO] World Health Organization. 1994. International Statistical Classification of Diseases and Related Health Problems, 10th Revision. Geneva: WHO.