Further support for the statins as antiinflammatory and immunomodulatory agents: Comment on the review by Abeles and Pillinger and the editorial by Arnaud and Mach [10]

Arthritis and Rheumatism

Volumn 54, Issue 7, 2006, Pages 2347-

  Schikler, Kenneth N ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOMODULATING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; MEVALONATE KINASE; SIMVASTATIN;

ANTIINFLAMMATORY ACTIVITY; CYTOKINE RELEASE; HUMAN; HYPERIMMUNOGLOBULINEMIA D AND PERIODIC FEVER SYNDROME; IMMUNOMODULATION; LETTER; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNOGLOBULIN D; IMMUNOLOGIC FACTORS; INTERLEUKIN-1; INTERLEUKIN-6; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RHEUMATIC DISEASES; SIMVASTATIN; SYNDROME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33745899931     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21959     Document Type: Letter

References (4)

1. Abeles AM, Pillinger MH. Statins as antiinflammatory and immunomodulatory agents: a future in rheumatologic therapy? [review]. Arthritis Rheum 2006;54:393-407.
2. Arnaud C, Mach F. Potential antiinflammatory and immunomodulatory effects of statins in rheumatologic therapy [editorial]. Arthritis Rheum 2006;54:390-2.
3. Simon A, Drewe E, van der Meer JW, Powell RJ, Kelley RI, Stalenhoef AF, et al. Simvastatin treatment for inflammatory attacks of the hyperimmunoglobulinemia D and periodic fever syndrome. Clin Pharmacol Ther 2004;75:476-83.
4. Drenth JP, van der Meer JW, Kushner I. Unstimulated peripheral blood mononuclear cells from patients with the hyper-IgD syndrome produce cytokines capable of potent induction of C-reactive protein and serum amyloid A in Hep3B cells. J Immunol 1996;157:400-4.