Homocysteine, B vitamins, and cardiovascular disease [4]

New England Journal of Medicine

Volumn 355, Issue 2, 2006, Pages 205-206

  De Craen, Anton J M ^a   Stott, David J ^b   Westendorp, Rudi G J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b GLASGOW ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID; HOMOCYSTEINE; VITAMIN B GROUP;

AMINO ACID BLOOD LEVEL; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL TRIAL; COGNITIVE DEFECT; DEMENTIA; DRUG BLOOD LEVEL; FAMILIAL DISEASE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HYPERHOMOCYSTEINEMIA; ISCHEMIC HEART DISEASE; LETTER; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RISK FACTOR;

CARDIOVASCULAR DISEASES; DEMENTIA; FOLIC ACID; HUMANS; HYPERHOMOCYSTEINEMIA; VASCULAR DISEASES; VITAMIN B 12; VITAMIN B 6; VITAMIN B COMPLEX;

EID: 33745896524     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc061259     Document Type: Letter

References (5)

1. The Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med 2006;354:1567-77.
2. Bønaa KH, Njølstad I, Ueland PM, et al. Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med 2006;354:1578-88.
3. Stott DJ, MacIntosh G, Lowe GD, et al. Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. Am J Clin Nutr 2005;82:1320-6.
4. Lewis SJ, Ebrahim S, Davey Smith G. Meta-analysis of MTHFR 677C→T polymorphism and coronary heart disease: does totality of evidence support causal role for homocysteine and preventive potential of folate? BMJ 2005;331:1053-6.
5. Mooijaart SP, Gussekloo J, Frölich M, et al. Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study. Am J Clin Nutr 2005;82:866-71.