Most commercial insulin assays fail to detect recombinant insulin analogues

Annals of Clinical Biochemistry

Volumn 43, Issue 4, 2006, Pages 306-308

  Heald, A H ^a,b   Bhattacharya, B ^b   Cooper, H ^b   Ullah, A ^b   McCulloch, A ^b   Smellie, S ^b   Wark, G ^c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b BISHOP AUCKLAND GENERAL HOSPITAL   (United Kingdom)

^c ROYAL SURREY COUNTY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN ASPART; INSULIN DETEMIR; ISOPHANE INSULIN; NEUTRAL INSULIN; RECOMBINANT HUMAN INSULIN;

ADULT; ARTICLE; CASE REPORT; CROSS REACTION; DIAGNOSTIC ERROR; DRUG EFFECT; DRUG MECHANISM; HUMAN; IMMUNOASSAY; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; INTOXICATION; MALE; MEDICAL SOCIETY; PATIENT COMPLIANCE; PRIORITY JOURNAL; QUALITY CONTROL;

ADOLESCENT; CHEMISTRY, CLINICAL; DIABETES MELLITUS; HUMANS; INSULIN; MALE; MULTICENTER STUDIES; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS;

EID: 33745893783     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/000456306777695690     Document Type: Article

References (4)

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2. Owen WE, Roberts WL. Cross-reactivity of three recombinant insulin analogs with five commercial insulin immunoassays. Clin Chem 2004; 50: 257-9
3. Bowsher RR, Lynch RA, Brown-Augsburger P, et al. Sensitive RIA for the specific determination of insulin lispro. Clin Chem 1999; 45: 104-10
4. Andersen L, Jorgensen PN, Jensen LB, Walsh D. A new insulin immunoassay specific for the rapid-acting insulin analog, insulin aspart, suitable for bioavailability, bioequivalence, and pharmacokinetic studies. Clin Biochem 2000; 33: 627-33