메뉴 건너뛰기




Volumn 1759, Issue 5, 2006, Pages 247-256

The role of Sp1 and Sp3 in the constitutive DPYD gene expression

Author keywords

Dihydropyrimidine dehydrogenase; DPYD; Promoter; Sp1

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

EID: 33745886277     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbaexp.2006.05.001     Document Type: Article
Times cited : (27)

References (40)
  • 1
    • 0032862086 scopus 로고    scopus 로고
    • Regulation of dihydropyrimidine dehydrogenase in colorectal cancer
    • Johnston S.J., Ridge S.A., Cassidy J., and McLeod H.L. Regulation of dihydropyrimidine dehydrogenase in colorectal cancer. Clin. Cancer Res. 5 (1999) 2566-2570
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2566-2570
    • Johnston, S.J.1    Ridge, S.A.2    Cassidy, J.3    McLeod, H.L.4
  • 2
    • 0034984031 scopus 로고    scopus 로고
    • Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil
    • Johnson M.R., and Diasio R.B. Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil. Adv. Enzyme Regul. 41 (2001) 151-157
    • (2001) Adv. Enzyme Regul. , vol.41 , pp. 151-157
    • Johnson, M.R.1    Diasio, R.B.2
  • 3
    • 0036020649 scopus 로고    scopus 로고
    • Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics
    • Mattison L.K., Soong R., and Diasio R.B. Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics. Pharmacogenomics 3 (2002) 485-492
    • (2002) Pharmacogenomics , vol.3 , pp. 485-492
    • Mattison, L.K.1    Soong, R.2    Diasio, R.B.3
  • 4
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio R.B., and Harris B.E. Clinical pharmacology of 5-fluorouracil. Clin. Pharmacokinet. 16 (1989) 215-237
    • (1989) Clin. Pharmacokinet. , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 5
    • 0035865277 scopus 로고    scopus 로고
    • Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil
    • Dobritzsch D., Schneider G., Schnackerz K.D., and Lindqvist Y. Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J. 20 (2001) 650-660
    • (2001) EMBO J. , vol.20 , pp. 650-660
    • Dobritzsch, D.1    Schneider, G.2    Schnackerz, K.D.3    Lindqvist, Y.4
  • 6
    • 0032748608 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistance
    • Diasio R.B., and Johnson M.R. Dihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistance. Clin. Cancer Res. 5 (1999) 2672-2673
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2672-2673
    • Diasio, R.B.1    Johnson, M.R.2
  • 9
    • 0015091901 scopus 로고
    • Dihydrouracil dehydrogenase activity in normal, differentiating and regenerating liver and in hepatomas
    • Queener S.F., Morris H.P., and Weber G. Dihydrouracil dehydrogenase activity in normal, differentiating and regenerating liver and in hepatomas. Cancer Res. 31 (1971) 1004-1009
    • (1971) Cancer Res. , vol.31 , pp. 1004-1009
    • Queener, S.F.1    Morris, H.P.2    Weber, G.3
  • 10
    • 0141961729 scopus 로고    scopus 로고
    • Effect of 5-fluorouracil and epidermal growth factor on cell growth and dihydropyrimidine dehydrogenase regulation in human uterine cervical carcinoma SKG-IIIb cells
    • Kashima N., Ueda M., and Kanazawa J. Effect of 5-fluorouracil and epidermal growth factor on cell growth and dihydropyrimidine dehydrogenase regulation in human uterine cervical carcinoma SKG-IIIb cells. Cancer Sci. 94 (2003) 821-825
    • (2003) Cancer Sci. , vol.94 , pp. 821-825
    • Kashima, N.1    Ueda, M.2    Kanazawa, J.3
  • 11
    • 0024267360 scopus 로고
    • Circadian rhythm of rat liver dihydropyrimidine dehydrogenase. Possible relevance to fluoropyrimidine chemotherapy
    • Harris B.E., Song R.L., He Y.J., Soong S.J., and Diasio R.B. Circadian rhythm of rat liver dihydropyrimidine dehydrogenase. Possible relevance to fluoropyrimidine chemotherapy. Biochem. Pharmacol. 37 (1988) 4759-4762
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 4759-4762
    • Harris, B.E.1    Song, R.L.2    He, Y.J.3    Soong, S.J.4    Diasio, R.B.5
  • 12
    • 0025058867 scopus 로고
    • Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion
    • Harris B.E., Song R., Soong S.J., and Diasio R.B. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res. 50 (1990) 197-201
    • (1990) Cancer Res. , vol.50 , pp. 197-201
    • Harris, B.E.1    Song, R.2    Soong, S.J.3    Diasio, R.B.4
  • 15
    • 4944261919 scopus 로고    scopus 로고
    • Population study of expression of thymidylate synthase and dihydropyrimidine dehydrogenase in patients with solid tumors
    • Fukushima M., Morita M., Ikeda K., and Nagayama S. Population study of expression of thymidylate synthase and dihydropyrimidine dehydrogenase in patients with solid tumors. Int. J. Mol. Med. 12 (2003) 839-844
    • (2003) Int. J. Mol. Med. , vol.12 , pp. 839-844
    • Fukushima, M.1    Morita, M.2    Ikeda, K.3    Nagayama, S.4
  • 18
    • 0034320204 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase activity and mRNA expression in advanced gastric cancer analyzed in relation to effectiveness of preoperative 5-fluorouracil-based chemotherapy
    • Takabayashi A., Iwata S., Kawai Y., Kanai M., Taki Y., Takechi T., and Fukushima M. Dihydropyrimidine dehydrogenase activity and mRNA expression in advanced gastric cancer analyzed in relation to effectiveness of preoperative 5-fluorouracil-based chemotherapy. Int. J. Oncol. 17 (2000) 889-895
    • (2000) Int. J. Oncol. , vol.17 , pp. 889-895
    • Takabayashi, A.1    Iwata, S.2    Kawai, Y.3    Kanai, M.4    Taki, Y.5    Takechi, T.6    Fukushima, M.7
  • 20
    • 0034651781 scopus 로고    scopus 로고
    • Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction
    • Johnson M.R., Wang K., Smith J.B., Heslin M.J., and Diasio R.B. Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Anal. Biochem. 278 (2000) 175-184
    • (2000) Anal. Biochem. , vol.278 , pp. 175-184
    • Johnson, M.R.1    Wang, K.2    Smith, J.B.3    Heslin, M.J.4    Diasio, R.B.5
  • 21
    • 0034670091 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human dihydropyrimidine dehydrogenase promoter
    • Shestopal S.A., Johnson M.R., and Diasio R.B. Molecular cloning and characterization of the human dihydropyrimidine dehydrogenase promoter. Biochim. Biophys. Acta 1494 (2000) 162-169
    • (2000) Biochim. Biophys. Acta , vol.1494 , pp. 162-169
    • Shestopal, S.A.1    Johnson, M.R.2    Diasio, R.B.3
  • 23
    • 0024276524 scopus 로고
    • Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif
    • Courey A.J., and Tjian R. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 55 (1988) 887-898
    • (1988) Cell , vol.55 , pp. 887-898
    • Courey, A.J.1    Tjian, R.2
  • 24
    • 4744375522 scopus 로고    scopus 로고
    • Complexity of translationally controlled transcription factor Sp3 isoform expression
    • Sapetschnig A., Koch F., Rischitor G., Mennenga T., and Suske G. Complexity of translationally controlled transcription factor Sp3 isoform expression. J. Biol. Chem. 279 (2004) 42095-42105
    • (2004) J. Biol. Chem. , vol.279 , pp. 42095-42105
    • Sapetschnig, A.1    Koch, F.2    Rischitor, G.3    Mennenga, T.4    Suske, G.5
  • 25
    • 24344445230 scopus 로고    scopus 로고
    • Differential intranuclear organization of transcription factors sp1 and sp3
    • He S., Sun J.M., Li L., and Davie J.R. Differential intranuclear organization of transcription factors sp1 and sp3. Mol. Biol. Cell 16 (2005) 4073-4083
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4073-4083
    • He, S.1    Sun, J.M.2    Li, L.3    Davie, J.R.4
  • 26
    • 33645650679 scopus 로고    scopus 로고
    • Activation of the RNA-dependent protein kinase PKR promoter in the absence of interferon is dependent upon Sp proteins
    • Das S., Ward S.V., Tacke R.S., Suske G., and Samuel C.E. Activation of the RNA-dependent protein kinase PKR promoter in the absence of interferon is dependent upon Sp proteins. J. Biol. Chem. 281 6 (2005) 3244-3253
    • (2005) J. Biol. Chem. , vol.281 , Issue.6 , pp. 3244-3253
    • Das, S.1    Ward, S.V.2    Tacke, R.S.3    Suske, G.4    Samuel, C.E.5
  • 27
    • 0034929708 scopus 로고    scopus 로고
    • Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer
    • Black A.R., Black J.D., and Azizkhan-Clifford J. Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer. J. Cell. Physiol. 188 (2001) 143-160
    • (2001) J. Cell. Physiol. , vol.188 , pp. 143-160
    • Black, A.R.1    Black, J.D.2    Azizkhan-Clifford, J.3
  • 28
    • 31144452788 scopus 로고    scopus 로고
    • GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site
    • Dishart D., Schnur N., Klan N., Werz O., Steinhilber D., Samuelsson B., and Radmark O. GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site. Biochim. Biophys. Acta 1738 (2005) 37-47
    • (2005) Biochim. Biophys. Acta , vol.1738 , pp. 37-47
    • Dishart, D.1    Schnur, N.2    Klan, N.3    Werz, O.4    Steinhilber, D.5    Samuelsson, B.6    Radmark, O.7
  • 29
    • 0033200098 scopus 로고    scopus 로고
    • DNA binding site selection by RNA polymerase II TAFs: a TAF(II)250-TAF(II)150 complex recognizes the initiator
    • Chalkley G.E., and Verrijzer C.P. DNA binding site selection by RNA polymerase II TAFs: a TAF(II)250-TAF(II)150 complex recognizes the initiator. EMBO J. 18 (1999) 4835-4845
    • (1999) EMBO J. , vol.18 , pp. 4835-4845
    • Chalkley, G.E.1    Verrijzer, C.P.2
  • 30
    • 0033569907 scopus 로고    scopus 로고
    • Context-dependent transcriptional regulation
    • Fry C.J., and Farnham P.J. Context-dependent transcriptional regulation. J. Biol. Chem. 274 (1999) 29583-29586
    • (1999) J. Biol. Chem. , vol.274 , pp. 29583-29586
    • Fry, C.J.1    Farnham, P.J.2
  • 31
    • 85047696724 scopus 로고    scopus 로고
    • Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells
    • Grinstein E., Jundt F., Weinert I., Wernet P., and Royer H.D. Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells. Oncogene 21 (2002) 1485-1492
    • (2002) Oncogene , vol.21 , pp. 1485-1492
    • Grinstein, E.1    Jundt, F.2    Weinert, I.3    Wernet, P.4    Royer, H.D.5
  • 32
    • 0037980189 scopus 로고    scopus 로고
    • The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression
    • Wei Q., Miskimins W.K., and Miskimins R. The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression. Mol. Cell. Biol. 23 (2003) 4035-4045
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4035-4045
    • Wei, Q.1    Miskimins, W.K.2    Miskimins, R.3
  • 33
    • 12844287625 scopus 로고    scopus 로고
    • Sp1 transcription factor expression is regulated by estrogen-related receptor alpha1
    • Sumi D., and Ignarro L.J. Sp1 transcription factor expression is regulated by estrogen-related receptor alpha1. Biochem. Biophys. Res. Commun. 328 (2005) 165-172
    • (2005) Biochem. Biophys. Res. Commun. , vol.328 , pp. 165-172
    • Sumi, D.1    Ignarro, L.J.2
  • 36
    • 0032857460 scopus 로고    scopus 로고
    • The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells
    • Qin H., Sun Y., and Benveniste E.N. The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells. J. Biol. Chem. 274 (1999) 29130-29137
    • (1999) J. Biol. Chem. , vol.274 , pp. 29130-29137
    • Qin, H.1    Sun, Y.2    Benveniste, E.N.3
  • 37
    • 0842269303 scopus 로고    scopus 로고
    • CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene
    • Pang R.T., Lee L.T., Ng S.S., Yung W.H., and Chow B.K. CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene. Mol. Endocrinol. 18 (2004) 471-483
    • (2004) Mol. Endocrinol. , vol.18 , pp. 471-483
    • Pang, R.T.1    Lee, L.T.2    Ng, S.S.3    Yung, W.H.4    Chow, B.K.5
  • 38
    • 0141592508 scopus 로고    scopus 로고
    • Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation
    • Wong W.K., Chen K., and Shih J.C. Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation. J. Biol. Chem. 278 (2003) 36227-36235
    • (2003) J. Biol. Chem. , vol.278 , pp. 36227-36235
    • Wong, W.K.1    Chen, K.2    Shih, J.C.3
  • 39
    • 0345830050 scopus 로고    scopus 로고
    • Down-regulation of human type II collagen gene expression by transforming growth factor-beta 1 (TGF-beta 1) in articular chondrocytes involves SP3/SP1 ratio
    • Chadjichristos C., Ghayor C., Herrouin J.F., Ala-Kokko L., Suske G., Pujol J.P., and Galera P. Down-regulation of human type II collagen gene expression by transforming growth factor-beta 1 (TGF-beta 1) in articular chondrocytes involves SP3/SP1 ratio. J. Biol. Chem. 277 (2002) 43903-43917
    • (2002) J. Biol. Chem. , vol.277 , pp. 43903-43917
    • Chadjichristos, C.1    Ghayor, C.2    Herrouin, J.F.3    Ala-Kokko, L.4    Suske, G.5    Pujol, J.P.6    Galera, P.7
  • 40
    • 0041804297 scopus 로고    scopus 로고
    • 5-fluorouracil and dihydropyrimidine dehydrogenase
    • Kubota T. 5-fluorouracil and dihydropyrimidine dehydrogenase. Int. J. Clin. Oncol. 8 (2003) 127-131
    • (2003) Int. J. Clin. Oncol. , vol.8 , pp. 127-131
    • Kubota, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.