Experimental chemical carcinogenesis: Fundamental and predictive rôle in protecting human health in the 1930s-1970s

European Journal of Oncology

Volumn 11, Issue 1, 2006, Pages 5-13

  Tomatis, Lorenzo ^a  

^a International Society of Doctors for the Environment (ISDE)   (Italy)

Author keywords

Carcinogenicity tests; Protection of human health

Indexed keywords

4 DIMETHYLAMINOAZOBENZENE; CARCINOGEN; FOOD ADDITIVE; HYDROCARBON; PESTICIDE; THALIDOMIDE; TOXIC SUBSTANCE;

CANCER PREVENTION; CARCINOGEN TESTING; CARCINOGENESIS; CARCINOGENICITY; EXPERIMENTAL NEOPLASM; HEALTH CARE; HUMAN; LONG TERM CARE; NONHUMAN; PUBLIC HEALTH SERVICE; REVIEW; WORLD HEALTH ORGANIZATION;

EID: 33745874693     PISSN: 11286598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (87)

1. Miller EC, Miller JA. Some historical perspectives on the metabolism of xenobiotic chemicals to reactive electrophiles. In Bioactivation of Foreign Compounds. Academic Press, 1985, 3-28.
2. Lawley PD. Historical origins of current concepts of carcinogenesis. Adv Cancer Res 1994; 65: 17-111.
3. Hill J. Cautious against the immoderate use of snuff. London: R. Baldwin and J. Jackson, 1761.
4. Pott P. Chirurgical observations relative to the cataract, the polypus of the nose, the cancer of the scrotum, the different kinds of ruptures and the mortifications of the toes ands feet. London: Hawes, Clarke and Collins, 1775.
5. Sommering S. De morbis vasorum absorbentium corporis humani. Frankfurt: Varrentrap and Wenner, 1795.
6. Hutchinson J. On some examples of arsenic-keratosis of the skin and of arsenic-cancer. Trans Path Soc London 1888; 39: 352-63.
7. Rehn L. Bladder tumours in fuchsin workers. Arch fur Kin Chir 1895; 50: 588-600.
8. Roentgen WC. Ueber eine neue Art von Strahlen. Sitzungsber Phys Med Gesellsch Wurtzb 1895; 132-41.
9. Frieben A. Demonstration eines cancroid der rechten Handruckens, das sich nach langdauernder Einwirkung von Roentgenstrahlen entwickelt hat. Fortschr Roentgenstr 1902; 6: 106-11.
10. Sick H. Karzinom der Haut das auf dem Bode eines Roentgenulkcus entstanden ist. Muench Mwed Wochenschr 1902; 50:1445.
11. Rous P. A sarcoma of the fowl transmissible by an agent separable from the tumor cells. J Exp Med 1911; 13: 397-411.
12. Triolo VA. Nineteenth century foundation of cancer research. Origins of experimental research. Cancer Res 1964; 24: 4-27.
13. Yamagiwa K, Ichikawa K. Experimentelle Studien ueber die Pathogenese der Epithelialgeschwuelste. Mitt Med Ges 1915; 15: 295-344.
14. Tsutsui H. Ueber das kuenstlich erzeugte Cancroid bei der Maus. Gann 1918; 12: 17-21.
15. Murray JA. Experimental tar cancer in mice. Brit Med J 1921; 2: 795.
16. International Agency for Research on Cancer. Monographs on the evaluation of carcinogenic risk of chemicals to man. Vol. 3. Certain polycyclic aromatic hydrocarbons and heterocyclic Compounds. Lyon: IARC, 1973.
17. Passey RD. Experimental soot cancer. Br Med J 1922; ii: 1112-3.
18. Shimkin MB. Some classics of experimental oncology. NIH Publication No. 80-2150. Washington, DC: US Government Printing Office, 1980.
19. Kennaway EL, Hieger I. Carcinogenic substances and their fluorescence spectrum. Br Med J 1930; 1: 1044-6.
20. Cook JW, Hieger I, Kennaway L, et al. The production of cancer by pure hydrocarbons. Part 1. Proc Royal Soc 1932; 111: 455-84.
21. Murphy JB, Sturm E. Primary lung tumors in mice following the cutaneous application of coal tar. J Exp Med 1925; 42: 693-700.
22. Sasaki T, Yoshida T. Experimentelle Erzeugung des Leberkarzinom durch Futterung mit o-Aminoazotoluol. Virchows Arch Path Anat 1935; 295: 175-200.
23. Berenblum I. Cancer research in historical perspective: an autobiographical essay. Cancer Res 1977; 37: 1-7.
24. Lacassagne A. Apparition de cancers de la mammelle chez la souris male, soumise a des injections de folliculine. Comptes Rend Acad Sci 1932; 195: 630-2.
25. Berenblum I. The mechanism of carcinogenesis: a study of the significance of carcinogenic action and related phenomena. Cancer Res 1941; 1: 897-914.
26. Rous P, Kidd JG. Conditional neoplasms and subthreshold neoplastic states. A study of the tar tumors of rabbits. J Exp Med 1941; 73: 365-90.
27. Friedenwald WF, Rous P. The initiating and promoting elements in tumor production. J Exp Med 1944; 80: 101-6.
28. Mottram JC. On the origin of tar tumours in mice. J Pathol Bacteriol 1935; 40: 407-9.
29. Berenblum I, Shubik P. A new quantitative approach to the study of the stages of chemical carcinogenesis in the mouse's skin. Brit J Cancer 1947; 1: 383-91.
30. Berenblum I, Shubik P. An experimental study of the initiating stage of carcinogenesis and a re-examination of the somatic mutation theory of cancer. Br J Cancer 1949; 3: 109-18.
31. Foulds L. Neoplastic development, vol.1. London and New York, Academic Press, 1969.
32. Pilot HC. The molecular biology of carcinogenesis. Cancer 1993; 72: 603-7.
33. Boyland E, Levi AA. Metabolism of polycyclic compounds. 1. Production of dihydroxydihydro-anthracene from anthracene. Biochem J 1935; 29: 2679-83.
34. Boyland E. Chemical carcinogenesis and experimental chemotherapy. Yale J Biol Med 1948; 20: 321-41.
35. Boyland E. Different Types of Carcinogens and Their possible Modes of Action. Cancer Res 1952; 12: 77-84.
36. Miller JA. Brief history of chemical carcinogenesis. Cancer Let 1994; 83: 9-14.
37. Miller EC, Miller JA. The presence and significance of bound aminoazodyes in the livers of rats fed p-dimethylaminoazobenzene. Cancer Res 1947; 7: 468-80.
38. Kinosita R. Studies on the cancerogenic chemical substances. Trans Jpn Pathol Soc 1937; 27: 665-727.
39. Cramer JW, Miller JA, Miller EC. N-hydroxylation: a new metabolic reaction observed in the rat with the carcinogen 2-acetylaminofluorene. J Biol Chem 1960; 235: 885-8.
40. Regulating Pesticides in Food: the Delaney paradox. Board on Agriculture. Washington, DC: National Academy Press, 1987.
41. Weisburger JH. The 37 year history of the Delaney Amendment. Exp Toxic Pathol 1996; 48: 183-8.
42. US EPA History. Http://www.epa.gov/history/topics/ tsca/01htm - updated Dec. 13th, 2004.
43. World Health Organization. Prevention of Cancer. WHO Technical Report Ser. no. 176. Geneva: WHO, 1964.
44. Tomatis L. The predictive value of rodent carcinogenicity tests in the evaluation of human risks. Ann Rev Pharmacol Toxicol 1979; 19: 511-30.
45. International Labour Office. Cancer of the bladder among workers in aniline factories. Studies and Reports, Series F, No.l. Geneva: ILO, 1921.
46. Hueper WC, et al. Experimental production of bladder tumors in dogs by administration of beta-naphtylamine. J Ind Hyg Toxicol 1937; 20: 46-84.
47. Wilson RH, DeEds F, Cox AJ Jr. Toxicity and carcinogenic activity of 2-acetylaminofluorene. Cancer Res 1941; 1: 595-608.
48. Walpole AL, Williams MHC, Roberts DC. The carcinogenic action of 4-aminodiphenyl and 3:2′dimethyl-4-aminodiphenyl. Br J Ind Med 1952; 9: 255.
49. Walpole AL, Williams MHC, Roberts DC. Tumours of the urinary bladder in dogs after ingestion of 4-aminodiphenyl. Br J Ind Med 1954; 11: 105.
50. Melick WF, Escue HM, Naryka JJ, et al. The first reported cases of human bladder tumours due to a new carcinogen-xenylamine. J Urol 1955; 74: 760.
51. International Agency for Research on Cancer. Monographs on the evaluation of carcinogenic risk of chemicals to man. Vol. 1. Lyon: IARC, 1972.
52. Greenstein JP. Biochemistry of Cancer. New York: Academic Press, 1954.
53. Shimkin MB, Andervont HB. Comparative carcinogenicity of three carcinogenic hydrocarbons. J Natl Cancer Inst 1940-41; 1: 57-62.
54. Shimkin MB. Pulmonary tumors in experimental animals. Adv Cancer Res 1955; 3: 223-67.
55. Turner FC. Experimental chemotherapy of tumors in mice. J Natl Cancer Inst 1943-44; 4: 265-70.
56. Nettleship A, Nenshaw PS. Induction of pulmonary tumors in mice with ethyl carbamate (urethane). J Natl Cancer Inst 1943-44; 4: 309-19.
57. Causation of cancer. Brit Med Bull 1958; 14 (2): 73-195.
58. Boyland E. Biological examination of carcinogenic substances. Br Med Bull 1958; 14: 93-8.
59. Walpole ZAL, Williams MHC. Aromatic amines as carcinogens in industry. Brit Med Bull 1958; 14: 141-5.
60. Bonser GM, Clayson DB, Juyll JW. Some aspects of the experimental induction of tumours of the bladder. Br Med Bull 1958; 14: 146-52.
61. Barnes JM, Schoental R. Experimental liver tumors. Br Med Bull 1958; 14: 165-7.
62. Graffi A, Bielka H. Probleme der experimentele Krebsforschung. Leipzig: Akademische Verlagsgesellschaft, Geest & Portig, 1959.
63. Hueper WC, Conway WD. Chemical carcinogenesis and cancers. Springfield, Ill: Charles C. Thomas, 1964.
64. Dally A. Thalidomide: was the tragedy preventable? Lancet 1998; 351: 1197-9.
65. US Food and Drug Administration milestones in US Food and Drug Law History, http://www.fda.gov/opacom/ backgrounders/miles.html (updated August 5, 2002).
66. Report of the Secretary's Commission on Pesticides and Their Relationship to Environmental Health. US Department of Health, Education and Welfare, US Government Printing Office, Washington, DC, 1969.
67. Innes JRM, Ulland BM, Valerio MG, et al. Bioassay of pesticides and industrial Chemicals of tumorigenicity in mice: a preliminary note. J Natl Cancer Inst 1969; 42: 1101-14.
68. Evaluation of Environmental Carcinogens. Report to the Surgeon General, USPHS, April 22, 1970. Ad Hoc Committee on the Evaluation of Low Levels of Environmental Chemical Carcinogens. Bethesda, MD: National Cancer Institute, 1970.
69. Chemicals and the Future of Man. Hearings before the Subcommittee on Executive Reorganization and Government Research of the Committee on Government Operations, United States Senate, Ninety-Second Congress, April 6 and 7, 1971. Washington, DC: US Government Printing Office, 1971.
70. Maltoni C, Conti B, Scarnato C. Benzene: a multi-potential carcinogen-result of long-term bioassays performed at the Bologna Institute of Oncology. Am J Ind Med 1983; 4: 441-5.
71. Waalkes MP, Ward JM, Diwan BA. Induction of tumors of the liver, lung, ovary and adrenal in adult mice after brief maternal gestational exposure to inorganic arsenic: promotional effects of postnatal phorbol ester exposure on hepatic and pulmonary, but not dermal cancers. Carcinogenesis 2004; 25: 133-41.
72. Van Duuren BL, Goldschmidt BM, Katz C, et al. Alpha-haloethers: a new type of alkylating carcinogen. Arch Environ Health 1968; 16: 472-6.
73. Van Duuren NL, Sivak A, Goldschmidt BM, et al. Carcinogenicity of halo-ethers. J Natl Cancer Inst 1969; 43: 481-6.
74. Laskin S, Kuschner M, Drew RT, et al. Tumors of the respiratory tract induced by inhalation of bis(chloromethyl)ether. Arch Environ Health 1971; 23: 135-6.
75. Figueroa WG, Raszkowski R, Weiss W. Lung cancer in chloromethyl methyl ether workers. New Eng J Med 1973; 288: 1096-9.
76. Thiess AM, Hey W, Zeller H. Zur Toxicologie von Dichlordimethylether - Verdacht auf kanzerogene Wirkung auch beim Menschen. Zb1 Arbeitsmed 1973; 23: 97-102.
77. Huff J. Chemical causally associated with cancers in humans and in laboratory animals. In Waalkes MP, Ward JM (eds.). Carcinogenesis. New York: Raven Press, 1994, 25-37.
78. Luch A. Nature and nurture. Lessons from chemical Carcinogenesis. Nature Rev Cancer 2005; 5: 113-25.
79. Hartwell JL. Survey of Compounds which have been tested for carcinogenic activity. Public Health Publication no. 149. Washington, DC: US Government Printing Office, 1951.
80. Shubik P, Hartwell JL. Survey of Compounds which have been tested for carcinogenic activity, Public Health Publication no. 149, Supplement 1 and Supplement 2. Washington, DC: US Government Printing Office, 1957 and 1969.
81. Carcinogenesis Program National Cancer Institute. Survey of Compounds which have been tested for Carcinogenic Activity. Public Health Publication no. 149. Washington, DC: US Government printing Office, 1971, 1973, 1974, 1976.
82. International Agency for Research on Cancer. Monographs on the evaluation of carcinogenic risks to humans. Vol. 1-85. Lyon: IARC, 1972-2005.
83. Hiatt HH, Watson JD, Winsten JA (eds). Origins of human cancer. Cold Spring Harbor: Cold Spring Harbor Laboratory, 1977.
84. Berenblum I (ed). Carcinogenicity testing. UICC Technical report Series, vol. 2. Geneva: International Union Against Cancer, 1969.
85. World Health Organization. Principles for the testing and evaluation of drugs for carcinogenicity. WHO Technical Report Series no. 426. Geneva: WHO, 1969.
86. Sontag J, Page N, Saffiotti U. Guidelines for carcinogen bioassay in small rodents. DHEW Publication no. 76-801 (NIH). Washintgton, DC: DHEW, 1976.
87. The testing of chemicals for carcinogenicity, mutagenicity and teratogenicity. Ottawa: Ministry of Health and Welfare, 1973.