HIV therapy, hepatitis C virus infection, antibiotics and obesity, a mitochondria killer mix? [5]

AIDS

Volumn 20, Issue 9, 2006, Pages 1343-1345

  Côté, Hélène C F ^a,b   Brumme, Zabrina L ^a,b   Chan, Jennifer W ^a   Guillemi, Silvia ^a   Montaner, Julio S G ^a,b   Harrigan, P Richard ^a,b  

^a ST PAUL S HOSPITAL   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AZITHROMYCIN; BENZATROPINE; CEFUROXIME; DIDANOSINE; LAMIVUDINE; LEVOFLOXACIN; LOXAPINE; METHADONE; NEVIRAPINE; NONSTEROID ANTIINFLAMMATORY AGENT; SALBUTAMOL; STAVUDINE; VALGANCICLOVIR; ZIDOVUDINE;

ADULT; ANTIBIOTIC THERAPY; AUTOPSY; BODY MASS; CASE REPORT; CD4+ T LYMPHOCYTE; FEMALE; HEPATITIS C; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOSPITAL ADMISSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LETTER; LIVER BIOPSY; LYMPHOCYTE COUNT; MITOCHONDRION; OBESITY; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; FATAL OUTCOME; FATTY LIVER; FEMALE; HEPACIVIRUS; HEPATITIS C; HIV INFECTIONS; HIV-1; HUMANS; MIDDLE AGED; MITOCHONDRIA, LIVER; OBESITY; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 33745866294     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000232250.89404.00     Document Type: Letter

References (15)

1. Arenas-Pinto A, Grant AD, Edwards S, Weller IV. Lactic acidosis in HIV infected patients: a systematic review of published cases. Sex Transm Infect 2003; 79:340-343.
2. Day L, Shikuma C, Gerschenson M. Mitochondrial injury in the pathogenesis of antiretroviral-induced hepatic steatosis and lactic acidemia. Mitochondrion 2004; 4:95-109.
3. Cote HC, Brumme ZL, Craib KJ, Alexander CS, Wynhoven B, Ting L, et al. Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients. N Engl J Med 2002; 346:811-820.
4. Cote HC, Yip B, Asselin JJ, Chan JW, Hogg RS, Harrigan PR, et al. Mitochondrial:nuclear DNA ratios in peripheral blood cells from human immunodeficiency virus (HIV)-infected patients who received selected HIV antiretroviral drug regimens. J Infect Dis 2003; 187:1972-1976.
5. Sha BE, Proia LA, Kessler HA. Adverse effects associated with use of nevirapine in HIV postexposure prophylaxis for 2 health care workers. JAMA 2000; 284:2723.
6. Coghlan ME, Sommadossi J-P, Jhala NC, Many WJ, Saag MS, Johnson VA. Symptomatic lactic acidosis in hospitalized antiretro viral-treated patients with human immunodeficiency virus infection: a report of 12 cases. Clin Infect Dis 2001; 33:1914-1921.
7. Walker UA, Bauerle J, Laguno M, Murillas J, Mauss S, Schmutz G, et al. Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine. Hepatology 2004; 39:311-317.
8. Nolan D, Hammond E, Martin A, Taylor L, Herrmann S, McKinnon E, et al. Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS 2003; 17:1329-1338.
9. Bonnet F, Balestre E, Bernardin E, Pellegrin JL, Neau D, Dabis F, and the Groupe d'Epidemologie CI inique du SIDA en Aquitaine. Risk factors for hyperlactataemia in HIV-infected patients, Aquitaine Cohort, 1999-2003. Antivir Chem Chemother 2005; 16:63-67.
10. Kontorinis N, Dieterich D. Hepatotoxicity of antiretroviral therapy. AIDS Rev 2003; 5:36-43.
11. Boudina S, Sena S, O'Neill BT, Tathireddy P, Young ME, Abel ED. Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation 2005; 112:2686-2695.
12. Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 2005; 307:384-387.
13. Pessayre D, Berson A, Fromenty B, Mansouri A. Mitochondria in steatohepatitis. Semin Liver Dis 2001; 21:57-69.
14. Kroon AM, Van den Bogert C. Antibacterial drugs and their interference with the biogenesis of mitochondria in animal and human cells. Pharm Weekbl Sci 1983; 5:81-87.
15. Hautekeete ML. Hepatotoxicity of antibiotics. Acta Gastroenterol Belg 1995; 58:290-296.