Experimental pig yersiniosis to assess attenuation of Yersinia enterocolitica O:8 mutant strains

FEMS Immunology and Medical Microbiology

Volumn 47, Issue 3, 2006, Pages 425-435

  Najdenski, Hristo ^a   Golkocheva, Elica ^a   Kussovski, Veselin ^a   Ivanova, Ekaterina ^a   Manov, Vasil ^b   Iliev, Mihail ^a   Vesselinova, Anna ^a   Bengoechea, José Antonio ^c,d   Skurnik, Mikael ^e  

^a INSTITUTE OF MICROBIOLOGY   (Bulgaria)

^b UNIVERSITY OF FORESTRY   (Bulgaria)

^c HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^d Fundacion Caubet CIMERA Illes Balears   (Spain)

^e UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Infection; Lipopolysaccharide; Mutants; Pigs; Yersinia enterocolitica

Indexed keywords

HYDROGEN PEROXIDE; IMMUNOGLOBULIN G; LIPOPOLYSACCHARIDE;

ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; BACTERIAL STRAIN; HEMATOLOGY; HISTOLOGY; IMMUNE RESPONSE; IMMUNOGENICITY; IN VITRO STUDY; LEUKOCYTOSIS; LYMPHOID TISSUE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEROTYPE; SERUM; SMALL INTESTINE; SWINE; SWINE DISEASE; TONSIL; WILD TYPE; YERSINIA ENTEROCOLITICA; YERSINIOSIS;

ANIMALS; ANTIBODIES, BACTERIAL; BLOOD BACTERICIDAL ACTIVITY; COMPLEMENT PATHWAY, ALTERNATIVE; COMPLEMENT PATHWAY, CLASSICAL; DISEASE MODELS, ANIMAL; HYDROGEN PEROXIDE; IMMUNOGLOBULINS; MACROPHAGES, PERITONEAL; MOUTH; MUTATION; NEUTROPHILS; O ANTIGENS; SWINE; VISCERA; YERSINIA ENTEROCOLITICA; YERSINIA INFECTIONS;

EID: 33745864375     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2006.00113.x     Document Type: Article

References (46)

1. Al-Hendy A, Toivanen P & Skurnik M (1992) Lipopolysaccharide O side chain of Yersinia enterocolitica O:3 is an essential virulence factor in an orally infected murine model. Infect Immun 60: 870-875.
2. Bengoechea JA, Pinta E, Oertelt C, Holst O, Radziejewska-Lebrecht J, Piotrowska-Seget Z, Venho R & Skurnik M (2002) Functional characterization of the Gne (UDP-N-acetylglucosamine-4-epimerase, EC 5.1.3.7.), Wzz (chain length determinant) and Wzy (O-antigen polymerase) of Yersinia enterocolitica serotype O:8. J Bacteriol 184: 4277-4287.
3. Bengoechea JA, Najdenski H & Skurnik M (2004) Essential role of the lipopolysaccharide O-antigen status of Yersinia enterocolitica O:8 in virulence and in the outer membrane regulatory network. Mol Microbiol 52: 451-469.
4. Bottone EJ, Gullans CR & Sierra MF (1987) Disease spectrum of Yersinia enterocolitica serogroup O:3, the predominant cause of human infection in New York City. Contrib Microbiol Immunol 9: 56-90.
5. 2 and NO response of peritoneal macrophages to Yersinia enterocolitica O:3 derivatives. Microb Infect 6: 207-212.
6. Cornelis GR (2002) Yersinia type III secretion:send in the effectors. J Cell Biol 158: 401-408.
7. Cover TL & Aber RC (1989) Yersinia enterocolitica. N Engl J Med 321: 16-24.
8. De Boer E & Nouws JFM (1991) Slaughter pigs and pork as a source of human pathogenic Yersinia enterocolitica. Int J Food Microbiol 12: 375-378.
9. Di Genaro M, Widmann M, Kramer U, Hitziger N, Bohn E & Autenrieth IB (2003) Attenuated Yersinia enterocolitica mutant strains exhibit differential virulence in cytokine-deficient mice:implications for the development of novel live carrier vaccines. Infect Immun 71: 1804-1812.
10. El Tahir Y & Skurnik M (2001) YadA, the multifaceted Yersinia adhesin. Int J Med Microbiol 291: 209-218.
11. Engels W, Endert J, Kamps MAF & Van Boven CPA (1985) Role of lipopolysaccharide in opsonization and phagocytosis of Pseudomonas aeruginosa. Infect Immun 49: 182-189.
12. Favre D, Cryz CJ Jr & Viret JF (1996) Construction and characterization of a potential live oral carrier-based vaccine against Vibrio cholerae O139. Infect Immun 64: 3565-3570.
13. Fukushima H, Nakamura R, Ito Y, Saito K, Tsubokura M & Otsuki K (1984) Ecological studies of Yersinia enterocolitica. II. Experimental infection with Y. enterocolitica in pigs. Vet Microbiol 9: 375-381.
14. Goldberg JB, Coyne MJ Jr, Neely AN & Holder IA (1995) A virulence of Pseudomonas aeruginosa algC mutant in a burned-mouse model of infection. Infect Immun 63: 4166-4169.
15. Gort AS & Miller VL (2000) Identification and characterization of Yersinia enterocolitica genes induced during systemic infection. Infect Immun 68: 6633-6642.
16. Harper P, Hornitzky MA & Rayward DG (1990) Enterocolitis in pigs associated with Yersinia pseudotuberculosis infection. Aust Vet J 67: 418-419.
17. Heesemann J, Gross U, Schmidt N & Laufs R (1986) Imunochemical analysis of plasmid-encoded proteins released by enteropathogenic Yersinia grown in calcium deficient medium. Infect Immun 2: 561-567.
18. Hurvell B (1981) Zoonotic Yersinia infection:host range clinical manifestations and transmission between animals and man. Yersinia enterocolitica (Bottone EJ, ed), pp. 145-160. CRC Press, Inc., Boca Raton, FL.
19. Igwe E, Rüssmann H, Roggenkamp A, Noll A, Autenrieth I & Heesemann J (1999) Rational live oral carrier vaccine design by mutating virulence-associated genes of Yersinia enterocolitica. Infect Immun 67: 5500-5507.
20. Klerx JPAM, Beukelman CJ, van Dijk H & Willers JMN (1983) Microassay for colorimetric estimation of complement activity in guinea pig, human and mouse serum. J Immunol Methods 63: 215-220.
21. Logue C, Sheridan JJ, McDowell DA & Blair IS (1995) A survey of the incidence of Yersinia on Irish meat and meat products. Contrib Microbiol Immunol 13: 77-79.
22. Mäkelä PH, Hovi M, Saxen H, Valtonen M & Valtonen V (1988) Salmonella, complement, and mouse macrophages. Immunol Lett 19: 217-222.
23. Miller SI, Ernst RK & Bader MW (2005) LPS, TLR4 and infectious disease diversity. Nat Rev Microbiol 3: 36-46.
24. Monack DM, Mecsas J, Ghori N & Falkow S (1997) Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death. Proc Natl Acad Sci USA 94: 10385-10390.
25. Najdenski H, Golkocheva E, Neykov P & Vesselinova A (2000) Serological screening of Yersinia infection in pigs by the classical agglutination test and improved ELISA. 16th Intern. Pig Vet. Soc. Congress, 17-20 September (Cargill C & McOrist S, eds), p. 241. Melbourne, Australia.
26. Najdenski H, Golkocheva E, Vesselinova A, Bengoechea JA & Skurnik M (2003) Expression of the O-antigen of lipopolysaccharide is essential for the virulence of Yersinia enterocolitica O:8 in experimental oral infection in rabbits. FEMS Immunol Med Microbiol 38: 97-106.
27. Nielsen B, Heisel C & Wingstrand A (1996) Time course of the serological response to Yersinia enterocolitica O:3 in experimentally infected pigs. Vet Microbiol 48: 293-303.
28. Nikolova S, Najdenski H, Wesselinova D, Vesselinova A, Kazatchca D & Neikov P (1997) Immunological and electronmicroscopic studies in pigs infected with Yersinia enterocolitica O:3. Zbl Bakt 286: 503-510.
29. Oertelt C, Lindner B, Skurnik M & Holst O (2001) Isolation and structural characterization of an R-form lipopolysaccharide from Yersinia enterocolitica serotype O:8. Eur J Biochem 268: 554-564.
30. Pai CH & De Stephano L (1982) Serum resistance associated with virulence in Yersinia enterocolitica. Infect Immun 35: 605-611.
31. Pelludat C, Hogardt M & Heesemann J (2002) Transfer of the core region genes of the Yersinia enterocolitica WA-C serotype O:8 high-pathogenicity island to Y. enterocolitica MRS, a strain with low levels of pathogenicity, confers a yersiniabactin biosynthesis phenotype and enhanced mouse virulence. Infect Immun 70: 1832-1841.
32. Pick E & Keisari Y (1980) A simple colorimetric method for measurement of hydrogen peroxide produced by cells in culture. J Immunol Methods 38: 161-70.
33. Porat R, Johns MA & McCabe WR (1987) Selective pressures and lipopolysaccharide subunits as determinants of resistance of clinical isolates of gram-negative bacilli to human serum. Infect Immun 55: 320-328.
34. Pujol C & Bliska BJ (2005) Turning Yersinia pathogenesis outside in subversion of macrophage function by intracellular yersiniae. Clin Immunol 114: 216-226.
35. 2 has a role in cellular regulation. Indian J Biochem Biophys 27: 269-274.
36. Roggenkamp A, Neuberger HR, Flugel A, Schmoll T & Heesemann J (1995) Substitution of two histidine residues in YadA protein of Yersinia enterocolitica abrogates collagen binding, cell adherence and mouse virulence. Mol Microbiol 16: 1207-1219.
37. Roggenkamp A, Bittner T, Leitritz L, Sing A & Heesemann J (1997) Contribution of the Mn-cofactored superoxide dismutase (SodA) to the virulence of Yersinia enterocolitica serotype 0:8. Infect Immun 64: 4705-4710.
38. Saebo A, Nyland H & Lassen J (1993) Yersinia enterocolitica infection - an unrecognized cause of acute and chronic neurological disease? A 10-year follow-up study on 458 hospitalized patients. Med Hypotheses 41: 282-286.
39. Schiemann D (1989) Yersinia enterocolitica and Yersinia pseudotuberculosis. Food Borne Bacterial Pathogens (Doyle MP, ed), pp. 602-672. Dekker Inc., New York.
40. Sisti F, Fernandez J, Rodriguez ME, Lagares A, Guiso N & Hozbor DF (2002) In vitro and in vivo characterization of a Bordetella bronchiseptica mutant strain with a deep rough lipopolysaccharide structure. Infect Immun 70: 1791-1798.
41. Spears PA, Temple LM & Orndorff PE (2000) A role for lipopolysaccharide in turkey tracheal colonization by Bordetella avium as demonstrated in vivo and in vitro. Mol Microbiol 36: 1425-1435.
42. Swindle M, Smith AC, Laber K, Goodrich JA & Bingel SA (2003) Biology and medicine of swine. Laboratory Animal Medicine and Management (Reuter JD & Suckow MA, eds), B2511.1103, International Veterinary Information Service, Ithaca, NY (http://www.ivis.org).
43. Vesselinova A, Veljanov D, Nikolova S, Najdenski H, Mladenov K & Sumnaliev M (1990) Immunomorphological changes in golden hamsters caused by Yersinia pestis EV. Schweiz Arch Tierhelh 132: 479-481.
44. Vissar LG, Annema A & van Furth R (1995) Role of Yops in inhibition of phagocytosis and killing of opsonized Yersinia enterocolitica by human granulocytes. Infect Immun 63: 2570-2575.
45. Vogel U, Autenrieth IB, Berner R & Heesemann J (1993) Role of plasmid-encoded antigens of Yersinia enterocolitica in humoral immunity against secondary Y. enterocolitica infection in mice. Microb Pathogen 15: 23-36.
46. Zhang L, Radziejewska-Lebrecht J, Krajewska-Pietrasik D, Toivanen P & Skurnik M (1997) Molecular and chemical characterization of the lipopolysaccharide O-chain biosynthesis of Yersinia enterocolitica serotype O:8 and role of O-chain in virulence. Mol Microbiol 23: 63-76.