Inhibition of hemoglobin S polymerization in vitro by a novel 15-mer EF-helix β73 histidine-containing peptide

Biochemistry

Volumn 45, Issue 27, 2006, Pages 8358-8367

  Akbar, Mohammed G K ^a   Tamura, Yutaka ^b   Ding, Min ^a   Ding, Hua ^b   Rosenblatt, Michael M ^c   Reddy, Konda S ^d   Surrey, Saul ^e   Adachi, Kazuhiko ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENZYME INHIBITION; HISTOLOGY; HYDROGEN BONDS; HYDROPHOBICITY; POLYMERIZATION; POLYMERS; REACTION KINETICS;

HYDROPHOBIC INTERACTIONS; INHIBITORY EFFECTS; PEPTIDES;

HEMOGLOBIN;

AMINO ACID; ASPARTIC ACID; HEMOGLOBIN S; HISTIDINE; PEPTIDE; THREONINE; VALINE;

ARTICLE; CIRCULAR DICHROISM; HYDROGEN BOND; IMAGE ANALYSIS; MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MICROARRAY;

CIRCULAR DICHROISM; HEMOGLOBIN, SICKLE; HISTIDINE; HUMANS; HYDROGEN BONDING; HYDROPHOBICITY; KINETICS; MICROSCOPY, INTERFERENCE; PEPTIDES; POLYMERS; PROTEIN ARRAY ANALYSIS; PROTEIN STRUCTURE, SECONDARY; SOLUBILITY;

EID: 33745863152     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0604734     Document Type: Article

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