The Positive Surgical Margin after Radical Prostatectomy-Why do we Still not Really Know What it Means?

European Urology

Volumn 50, Issue 2, 2006, Pages 199-201

  Graefen, Markus ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED CANCER; CANCER LOCALIZATION; CANCER PATIENT; CANCER SURGERY; EDITORIAL; FOLLOW UP; GLEASON SCORE; HUMAN; LYMPH NODE METASTASIS; OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATECTOMY; RISK FACTOR; SALVAGE THERAPY; SEMINAL VESICLE DISEASE; STATISTICAL ANALYSIS; SURGEON; SURGICAL PATIENT; TREATMENT OUTCOME;

DISEASE PROGRESSION; HUMANS; MALE; NEOPLASM RECURRENCE, LOCAL; PREDICTIVE VALUE OF TESTS; PROSTATECTOMY; PROSTATIC NEOPLASMS; RISK FACTORS;

EID: 33745845161     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2006.02.016     Document Type: Editorial

References (10)

1. Swindle P., Eastham J.A., Ohori M., et al. Do margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol 174 (2005) 903-907
2. Vis A.N., Schröder F.H., and van der Kwast T.H. The actual value of the surgical margin status as a predictor of disease progression in men with early prostate cancer. Eur Urol. 50 (2006) 258-265
3. Ohori M., Wheeler T.M., Kattan M.W., Goto Y., and Scardino P.T. Prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol 154 (1995) 1818-1824
4. Stamey T.A., McNeal J.E., Yemoto C.M., Sigal B.M., and Johnstone I.M. Biological determinants of cancer progression in men with prostate cancer. JAMA 281 (1999) 1395-1400
5. Graefen M., Noldus J., Pichlmeier U., et al. Early prostate-specific antigen relapse after radical retropubic prostatectomy: prediction on the basis of preoperative and postoperative tumor characteristics. Eur Urol 36 (1999) 21-30
6. Palisaar R.J., Graefen M., Karakiewicz P.I., et al. Assessment of clinical and pathologic characteristics predisposing to disease recurrence following radical prostatectomy in men with pathologically organ-confined prostate cancer. Eur Urol 41 (2002) 155-161
7. Palisaar R.J., Noldus J., Graefen M., Erbersdobler A., Haese A., and Huland H. Influence of nerve-sparing (NS) procedure during radical prostatectomy (RP) on margin status and biochemical failure. Eur Urol 47 (2005) 176-184
8. Graefen M., Walz J., and Huland H. Open retropubic nerve-sparing radical prostatectomy. Eur Urol 49 (2006) 38-48
9. Karakiewicz P.I., Eastham J.A., Graefen M., et al. Prognostic impact of positive surgical margins in surgically treated prostate cancer: multi-institutional assessment of 5831 patients. Urology 66 (2005) 1245-1250
10. Bolla M., van Poppel H., Collette L., et al. Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911). Lancet 366 (2005) 572-578