Towards safer, faster prenatal genetic tests: Novel unsupervised, automatic and robust methods of segmentation of nuclei and probes

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Volumn 3954 LNCS, Issue , 2006, Pages 437-450

  Restif, Christophe ^a  

^a OXFORD BROOKES UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHMIC LANGUAGES; CLINICAL LABORATORIES; IMAGE SEGMENTATION; IMAGING TECHNIQUES; MEDICAL APPLICATIONS; PROBES; SPURIOUS SIGNAL NOISE; TUNING;

CYTOMETRY MEDICAL IMAGING; EXPECTATION-MAXIMISATION ALGORITHM; NUCLEIC TEXTURES; PRENATAL GENETIC TESTS;

GENETIC ENGINEERING;

EID: 33745830427     PISSN: 03029743     EISSN: 16113349     Source Type: Book Series    
DOI: 10.1007/11744085_34     Document Type: Conference Paper

References (20)

1. Hohmann, H., Michel, S., Reiber, W., Gunther, M., Claussen, U., von Eggeling, F.: How to enrich and analyse fetal cells from maternal blood. In: Fetal Cells and Fetal DNA in Maternal Blood, Karger (2001) 47-55
2. Merchant, F.A., Castleman, K.R.: Strategies for automated fetal cell screening. Human Reproduction Update 8 (2002) 509-521
3. Fang, B., Hau, W., Lee, M.L.: On the accurate counting of tumor cells. IEEE Transactions on Nanobioscience 2 (2003) 94-103
4. Tanaka, T., Murase, Y., Oka, T.: Classification of skin tumors based on shape features of nuclei; In: Medicine and Biology Society. Volume 3. (2002) 1064-1066
5. Wu, K., Gauthier, D., Levine, M.D.: Live cell image segmentation. IEEE Transactions on Biomedical Engineering 42 (1995) 1-12
6. Lin, G., Adiga, U., Olson, K., Guzowski, J., Barnes, C., Roysam, B.: A hybrid 3D watershed algorithm incorporating gradient cues and object models for automatic segmentation of nuclei in confocal image stacks. Cytometry 56A (2003) 23-36
7. Lehmann, T., Bredno, J., Spitzer, K.: On the design of active contours for medical image segmentation. Methods of Information in Medicine 42 (2003) 89-98
8. Poon, S.S., Martens, U.M., Ward, R.K., Lansdorp, P.M.: Telomere length measurements using digital fluorescence microscopy. Cytometry 36 (1999) 267-278
9. Clocksin, W.F., Lerner, B.: Automatic analysis of fluorescence in-situ hybridisation images. In: British Machine Vision Conference. (2000) 666-674
10. Pelikan, D.M.V., Mesker, W.E., Scherjon, S.A., Kanhai, H.H.H., Tanke, H.J.: Improvement of the Kleihauer-Betke test by automated detection of fetal erythrocytes in maternal blood. Cytometry Part B (Clinical Cytometry) 54B (2003) 1-9
11. de Solorzano, C.O., Garcia Rodriguez, E., Johnes, A., Pinkel, D., Gray, J., Sudar, D., Lockett, S.: Segmentation of confocal microscope images of cell nuclei in thick tissue sections. Journal of Microscopy 193 (1999) 212-226
12. de Solorzano, C.O., Malladi, R., Lelievre, S., Lockett, S.: Segmentation of nuclei and cells using membrane related protein markers. Microscopy 201 (2001) 404-415
13. Bamford, P., Lovell, B.: Method for accurate unsupervised cell nucleus segmentation. In: IEEE Engineering in Medicine and Biology. Volume 1. (2001) 133-135
14. Netten, H., Young, I., van Vliet, L., Tanke, H., Vroljik, H., Sloos, W.: Automation of fluorescent dot counting in interphase cell nuclei. Cytometry 28 (1997) 1-10
15. Theodoridis, S., Koutroumbas, K.: Pattern Recognition. 2nd edn. Elsevier (2003)
16. Smith, S.W. In: The scientist and engineer's guide to digital signal processing. California Technical Publishing (1997) 11-34
17. Kutalik, Z., Razaz, M., Baranyi, J.: Automated spatial and temporal image analysis of bacterial cell growth. In: BMVA Spatiotemporal Image Processing. (2004)
18. Felzenszwalb, P.F., Huttenlocher, D.P.: Distance transforms of sampled functions. Technical report, Cornell University (2004) TR2004-1963.
19. Malpica, N., de Solorzano, C.O., Vaquero, J.J., Santos, A., Vallcorba, I., Garcia-Sagrado, J.M., del Pozo, P.: Applying watershed algorithms to the segmentation of clustered nuclei. Cytometry 28 (1997) 289-297
20. Restif, C., Clocksin, W.: Comparison of segmentation methods for cytometric assay. In: Medical Image Understanding and Analysis. (2004) 153-156