Serum leucine-rich alpha-2-glycoprotein-1 binds cytochrome c and inhibits antibody detection of this apoptotic marker in enzyme-linked immunosorbent assay

Apoptosis

Volumn 11, Issue 7, 2006, Pages 1121-1129

  Cummings, Chad ^a   Walder, Jennifer ^a   Treeful, Amy ^a   Jemmerson, Ronald ^b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b Mayo Mail Code 609   (United States)

Author keywords

Apoptotic marker; Cytochrome c; ELISA; Leucine rich alpha 2 glycoprotein 1; Leucine rich repeats

Indexed keywords

ALPHA2 GLYCOPROTEIN; CYTOCHROME C; LEUCINE RICH ALPHA2 GLYCOPROTEIN 1; UNCLASSIFIED DRUG;

ANTIBODY DETECTION; APOPTOSIS; ARTICLE; CHROMATOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; SENSITIVITY AND SPECIFICITY; SERUM;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BLOOD PROTEINS; CATTLE; CYTOCHROMES C; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOPROTEINS; HORSES; HUMANS; MICE; PROTEIN BINDING; RATS; REPRODUCIBILITY OF RESULTS; SERUM; SERUM ALBUMIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

BOS TAURUS;

EID: 33745830196     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-8159-3     Document Type: Article

References (33)

1. Newmeyer DD, Ferguson-Miller S (2003) Mitochondria: Releasing power tor life and unleashing the machineries of death. Cell 112:481-490
2. Jemmerson R, Dubinsky JM, Brustovetsky N (2005) Cytochrome c release from CNS mitochondria and potential for clinical intervention in apoptosis-mediated CNS diseases. Antiox Redox Signal 7:1158-1172
3. Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147-157
4. Zou H, Henzel WJ, Liu X, et al (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-413
5. Li P, Nijhawan D, Budihardjo I, et al (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489
6. Boehning D, Patterson RL, Sedaghat L, et al (2003) Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat Cell Biol 5:1051-1061
7. Nur-E-Kamal A, Gross SR, Pan Z, Balklava Z, et al (2004) Nuclear translocation of cytochrome c during apoptosis. J Biol Chem 279:24911-24914
8. Kagan VE, Borisenko GG, Tyurina YY, et al (2004) Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine. Free Rad Biol Med 37:1963-1985
9. Jemmerson R, Laplante B, Treeful A (2002) Release of intact, monomeric cytochrome c from apoptotic and necrotic cells. Cell Death Differ. 9:538-548
10. Renz A, Berdel WE, Kreuter M, Belka C, Schulze-Osthoff K, Los M (2001) Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo. Blood 98:1542-1548
11. Pullerits R, Bokarewa M Jonsson I-M, et al (2005) Extracellular cytochrome c, a mitochondrial apoptosis-related protein, induces arthritis. Rheumatology 44:32-39
12. Barczyk K, Kreuter M, Pryjma J, et al (2005) Serum cytochrome c indicates in vivo apoptosis and can serve as a prognostic marker during cancer therapy. Int J Cancer 116:167-173
13. Gvatua NA, Komissarenko SV, Skok MV, et al (1990) Determination of the concentration of cytochrome c and its antibodies in the blood serum for the diagnosis and prognosis of complications in myocardial infarct patients. Ter Arkh 62:58-61
14. Alleyne T, Joseph J, Sampson V (2001) Cytochrome c detection: a diagnostic marker for myocardial infarction. Appl Biochem Biotech 90:97-105
15. Ben-Ari Z, Schmilovotz-Weiss H, Belinki A, et al. (2003) Circulating soluble cytochrome c in liver disease as a marker of apoptosis. J Intern Med 254:168-175
16. Adachi N, Hirota M, Hamaguchi M, Okamoto K, et al (2004) Serum cytochrome c level as a prognostic indicator in patients with systemic inflammatory response syndrome. Clin Chim Acta 342:127136-
17. Nunoi H, Mercado MR, Mizukami T, et al (2005) Apoptosis under hypercytokinemia is a possible pathogenesis in influenza-associated encephalopathy. Pediatr Int 47:175-179
18. Engvall E (1980) Enzyme immunoassay ELISA and EMIT. Meth Enzymol 70:419-439
19. Urbanski GJ, Margoliash E (1976) The antigenicity of cytochrome c. In: M. Salton, (ed). The immunochemistry of enzymes and their antibodies: J. Wiley and Sons New York pp. 203-226
20. Goshorn SC, Retzel E, Jemmerson R (1991) Common structural features among monoclonal antibodies binding the same antigenic region of cytochromes. J Biol Chem 266:2134-2142
21. Minnerath JM, Crump BL, Margoliash E, Jemmerson R (1995) Major and minor epitopes on the self antigen mouse cytochrome c mapped by site-directed mutagenesis. Mol Immunol 32:795-803
22. Urbanski GJ Margoliash E (1977) Topographic determinants on cytochrome c. I. The complete antigenic structures of rabbit, mouse, and guanaco cytochromes c in rabbits and mice. J Immunol 118:1170-1180
23. Glatz JF, Veerkamp JH (1983) Removal of fatty acids from serum albumin by Lipidex 1000 chromatography. J Biochem Biophys Methods 8:57-61
24. Cotter R (1996) Time-of-flight mass spectrometry: Instrumentation and applications in biological research, American Chemical Society
25. Carlson SS, Mross GA, Wilson AC, et al (1977) Primary structure of mouse, rat, and guinea pig cytochrome c. Biochemistry 16:1437-1442
26. Brown JR (1975) Structure of bovine serum albumin. Fed Proc 34:591-591
27. O'Donnell LC, Druhan LJ, Avalos BR (2002) Molecular characterization and expression analysis of leucine-rich α2 glycoprotein, a novel marker of granulocytic differentiation. J Leuk Biol 72:478-485
28. 2-glycoprotein of human serum. Proc Natl Acad Sci USA 82:1906-1910
29. Kobe B, Kajava AV (2001) The leucine-rich repeat as a protein recognition motif. Curr Op Struct Biol 11:725-732
30. Sanishvili R, Volz KW, Westbrook EM, Margoliash E (1995) The low ionic strength crystal structure of horse cytochomre c at 2.1 Åresolution and comparison with its high ionic strength counterpart. Structure 3:707-716
31. Spector AA (1975) Fatty acid binding to plasma albumin. J Lipid Res 16:165-179
32. Tuominen EKJ, Wallace CJA, Kinnunen, PKJ (2002) Phospholipid-cytochrome c interaction. Evidence for the extended lipid anchorage. J Biol Chem 277:8822-8826.
33. Jemmerson R, Liu J, Hausauer D, Lam K-P, et al. (1999) conformational change in cytochrome c of apoptotic and necrotic cells is detected by monoclonal antibody binding and mimicked by association of the native antigen with synthetic phospholipids vesicles. Biochem 38:3599-3609