Discrimination of esterase and peptidase activities of acylaminoacyl peptidase from hyperthermophilic Aeropyrum pernix K1 by a single mutation

Journal of Biological Chemistry

Volumn 281, Issue 27, 2006, Pages 18618-18625

  Wang, Qiuyan ^a   Yang, Guangyu ^a   Liu, Yanli ^a   Feng, Yan ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; MUTAGENESIS; SUBSTRATES;

ACYLAMINOACYL PEPTIDASES; ESTERASE ACTIVITY; MOLECULAR DYNAMICS SIMULATIONS; SATURATION MUTAGENESIS;

ENZYMES;

ACYLAMINOACYL PEPTIDASE ENZYME; AMINO ACID; ARGININE; BACTERIAL ENZYME; ESTERASE; LEUCINE; OCTANOIC ACID; PEPTIDASE; UNCLASSIFIED DRUG;

AEROPYRUM; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HIGH THROUGHPUT SCREENING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; THERMOPHILIC BACTERIUM;

AEROPYRUM PERNIX;

EID: 33745826249     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M601015200     Document Type: Article

References (28)

1. Rawlings, N. D., Polgár, L., and Barrett, A. J., (1991) Biochem. J. 279, 907-908
2. Barrett, A. J., and Rawlings, N. D. (1992) Biol. Chem. Hoppe Seyler. 373, 353-360
3. Polgár, L. (2002) Cell. Mol. Life Sci. 59, 349-362
4. Szeltner, Z., Rea, D., Renner, V., Juliano, L., Fülöp, V., and Polgár, L. (2003) J. Biol. Chem. 278, 48786-48793
5. Rennex, D., Hemmings, B. A., Hofsteenge, J., and Stone, S. R. (1991) Biochemistry 30, 2195-2203
6. Rawlings, N. D., Polgár, L., and Barrett, A. J. (1991) Biochem. J. 279, 907-911
7. Polgár, L. (1994) in Prolyl Oligopeptidases (Barrett, A. J., ed) pp. 188-200, Academic Press, Inc., New York
8. Polgár, L. (2002) Curr. Med. Chem. Central Nervous System Agents 2, 251-257
9. Polgár, L. (1992) FEBS Lett. 311, 281-284
10. Gao, R., Feng, Y., Ishikawa, K., Ishida, H., Ando, S., Kosugi, Y., and Cao, S. (2003) J. Mol. Catal., B Enzym. 24, 1-8
11. Bartlam, M., Wang, G., Yang, H., Gao, R., Zhao, X., Xie, G., Cao, S., Feng, Y., and Rao, Z. (2004) Structure 12, 1481-1488
12. Venäläinen, J. I., Juvonen, R. O., and Männistö, P. T. (2004) Eur. J. Biochem. 271, 2705-2715
13. Fülöp, V., Szeltner, Z., Renner, V., and Polgár, L. (2001) J. Biol. Chem. 276, 1262-1262
14. Shan, L., Mathews, I. I., and Khosla, C. (2005) Proc. Natl. Acad. Sci. 102, 3599-3604
15. Zheng, L., Baumann, U., and Reymond, J. L. (2004) Nucleic Acids Res. 32, e115
16. Ayala, Y. M., and Di Cera, E. (2000) Protein Sci. 9, 1589-1593
17. Judice, W. A. S., Cezari, M. H. S., Lima, A. P. C. A., Scharfstein, J., Chagas, J. R., Tersariol, I. L. S., Juliano, M. A., and Juliano, L. (2001) Eur. J. Biochem. 268, 6578-6586
18. Krem, M. M., Prasad, S., and Di Cera, E. (2002) J. Biol. Chem. 277, 40260-40264
19. Bobofchak, K. M., Pineda, A. O., Mathews, F. S., and Di Cera, E. (2005) J. Biol. Chem. 280, 25644-25650
20. Rui, L., Kwon, Y., Fishman, A., Reardon, K. F., and Wood, T. K. (2004) Appl. Environ. Microbiol. 70, 3246-3252
21. De Simone, G., Mandrich, L., Menchise, V., Giordano, V., Febbraio, F., Rossi, M., Pedone, C., and Manco, G. (2004) J. Biol. Chem. 279, 6815-6823
22. De Simone, G., Menchise, V., Manco, G., Mandrich, L., Sorrentino, N., Lang, D., Rossi, M., and Pedone, C. (2001) J. Mol. Biol. 314, 507-518
23. Hemilä, H., Koivula, T. T., and Palva, I. (1994) Biochim. Biophys. Acta 1210, 249-253
24. Manco, G., Adinolfi, E., Pisani, F. M., Ottolina, G., Carrea, G., and Rossi, M. (1998) Protein Pept. Lett. 4, 375-382
25. Manco, G., Adinolfi, E., Pisani, F. M., Carratore, V., and Rossi, M. (1998) Biochem. J. 332, 203-212
26. Shindyalov, I. N., and Bourne, P. E. (1998) Protein Eng. 11, 739-747
27. Manco, G., Mandrich, L., and Rossi, M. (2001) J. Biol. Chem. 276, 37482-37490
28. Nardini, M., Lang, D. A., Liebeton, K., Jaeger, K. E., and Dijkstra, B. W. (2000) J. Biol. Chem. 275, 31219-31225