Treatment with anti-TNF monoclonal antibody (c5N) reduces the extent of induced endometriosis in the baboon

Human Reproduction

Volumn 21, Issue 7, 2006, Pages 1856-1862

  Falconer, H ^a   Mwenda, J M ^b   Chai, D C ^b   Wagner, C ^c   Song, X Y ^c   Mihalyi, A ^d   Simsa, P ^d   Kyama, C ^d   Cornillie, F J ^c   Bergqvist, A ^e   Fried, G ^a   D'Hooghe, Thomas M ^b,d  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b INSTITUTE OF PRIMATE RESEARCH   (Kenya)

^c CENTOCOR INC   (United States)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e DANDERYD HOSPITAL   (Sweden)

Author keywords

Anti TNF; Baboon; Cytokines; Endometriosis; Randomized controlled study

Indexed keywords

INFLIXIMAB; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY C5N; PLACEBO; TUMOR NECROSIS FACTOR ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BABOON; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG EFFICACY; ENDOMETRIOSIS; ENDOMETRIUM BIOPSY; FEMALE; FOLLOW UP; KENYA; LAPAROSCOPY; MEDICAL DOCUMENTATION; MENSTRUAL CYCLE; NONHUMAN; PAPIO ANUBIS; PELVIS; PROSPECTIVE STUDY; RANDOMIZATION; SURFACE PROPERTY; VIDEORECORDING; VOLUMETRY;

PAPIO; PAPIO ANUBIS; PAPIO HAMADRYAS; PRIMATES;

EID: 33745818582     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/del044     Document Type: Article

References (31)

1. Agnholt J, Kelsen J, Brandsborg B, Jakobsen NO and Dahlerup JF (2004) Increased production of granulocyte-macrophage colony-stimulating factor in Crohn's disease - a possible target for infliximab treatment. Eur J Gastroenterol Hepatol 16,639-641.
2. American Fertility Society (1985) Revised American Fertility Society classification of endometriosis. Fertil Steril 43,351-352.
3. American Society for Reproductive Medicine (1997) Revised American Society for Reproductive Medicine classification of endometriosis: 1996. Fertil Steril 67,817-821.
4. Barrier BF, Bates GW, Leland MM, Leach DA, Robinson RD and Propst AM (2003) Efficacy of anti-tumor necrosis factor therapy in the treatment of spontaneous endometriosis in baboons. Fertil Steril 81,775-779.
5. Blumenkrantz MJ, Gallagher N, Bashore RA and Tenckhoff H (1981) Retrograde menstruation in women undergoing chronic peritoneal dialysis. Obstet Gynecol 57,667-670.
6. Braun DP, Ding J and Dmowski WP (2002) Peritoneal fluid-mediated enhancement of eutopic and ectopic endometrial cell proliferation is dependent on tumor necrosis factor-alpha in women with endometriosis. Fertil Steril 78,727-732.
7. Carlson K, Miller B and Fowler FJ (1994) The Maine Women's Health Study: I. Outcomes of hysterectomy. Obstet Gynecol 83,556-565.
8. Colombel JF, Loftus EV Jr, Tremaine WJ, Egan LJ, Harmsen WS, Schleck CD, Zinsmeister AR, Sandborn WJ (2004) The safety profile of infliximab in patients with Crohn's disease: The Mayo clinic experience in 500 patients. Gastroenterology 126,19-31.
9. D'Antonio M, Martelli F, Peano S, Papoian R and Borrelli F (2000) Ability of recombinant human TNF binding protein-1 (r-hTBP-1) to inhibit the development of experimentally-induced endometriosis in rats. J Reprod Immunol 48,81-98.
10. D'Hooghe TM (1997) Clinical relevance of the baboon as a model for the study of endometriosis. Fertil Steril 68,613-625.
11. D'Hooghe TM, Bambra CS, Cornillie FJ, Isahakia M and Koninckx PR (1991) Prevalence and laparoscopic appearance of spontaneous endometriosis in the baboon (Papio anubis, Papio cynocephalus). Biol Reprod 45,411-416.
12. D'Hooghe TM, Bambra CS, Isahakia M and Koninckx PR (1992) Evolution of spontaneous endometriosis in the baboon (Papio anubis, Papio cynocephalus) over a 12-month period. Fertil Steril 58,409-412.
13. D'Hooghe TM, Bambra CS, Raeymaekers BM, De Jonge I, Hill JA and Koninckx PR (1995a) The effects of immunosuppression on development and progression of endometriosis in baboons (Papio anubis) Fertil Steril 64,172-178.
14. D'Hooghe TM, Bambra CS, Raeymaekers BM, De Jonge I, Lauweryns JM and Koninckx PR (1995b) Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis). Am J Obstet Gynecol 173,125-134.
15. D'Hooghe TM, Nugent NP, Cuneo S, Chai DC, Deer F, Debrock S, Kyama CM, MihalyiA and Mwenda JM (2006) Recombinant Human TNFRSF1A (r-hTBP1) Inhibits the development of endometriosis in baboons: A prospective, randomized, placebo- and drug-controlled study. Biol Reprod 74,131-136.
16. Di Sabatino A, Ciccocioppo R, Cinque B, Millimaggi D, Morera R, Ricevuti L, Cifone MG, Corazza GR (2004) Defective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn's disease. Gut 53,70-77.
17. Donnez J, Casanas-Roux F and Nisolle M (1993) In The Current Status of Endometriosis: Research and Management. Parthenon Publishing, Carnforth, UK, pp. 75-87.
18. Donnez J, Smoes P, Gillerot S, Casanas-Roux F and Nisolle M (1998) Vascular endothelial growth factor (VEGF) in endometriosis. Hum Reprod 13,1698-1699.
19. Gardiner TA, Gibson DS, de Gooyer TE, de la Cruz VF, McDonald DM and Stitt AW (2005) Inhibition of tumor necrosis factor-alpha improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy. Am J Pathol 166,637-644.
20. Halme J, Becker S, Hammond MG, Raj SG and Talbert LM (1984) Retrograde menstruation in healthy women and in patients with endometriosis. Obstet Gynecol 64,151-154.
21. Keane J, Gershon S, Wise RP, Mirabile-Levens E, Kasznica J, Schwieterman WD, Siegel JN and Braun MM (2001) Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 345,1098-1104.
22. Nisolle M and Donnez J (1997) Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril 68,585-596.
23. Nisolle M, Casanas-Roux F, Anaf V, Mine JM and Donnez J (1993) Morphometric study of the stromal vascularization in peritoneal endometriosis. Fertil Steril 59,681-684.
24. Redwine DB (2003) 'Invisible' microscopic endometriosis: A review. Gynecol Obstet Invest 55,61-62.
25. Sampson JA (1927) Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the pelvic cavity. Am J Obstet Gynecol 14,422-469.
26. Shen C, Maerten P, Geboes K, Van Assche G, Rutgeerts P and Ceuppens JL (2005) Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model. Clin Immunol 115,250-259.
27. Slifman NR, Gershon SK, Lee JH, Edwards ET and Braun MM (2003) Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents. Arthritis Rheum 48,319-324.
28. Song XY, Fox F, Gallo MA, Rosenberg A, Jordan R, Shealy D and Wagner C (2002) Effects of 2 different anti-tumor necrosis factor-alpha agents in a primate model of subcutaneous abscess formation. J Infect Dis 15 185,204-213.
29. True DG, Penmetcha M and Peckham SJ (2002) Disseminated cryptococcal infection in rheumatoid arthritis treated with methotrexate and infliximab. J Rheumatol 29,1561-1563.
30. Wieser F, Fabjani G, Tempfer C, Schneeberger C, Zeillinger R, Huber JC and Wenzl R (2002) Tumor necrosis factor-alpha promotor polymorphisms and endometriosis. J Soc Gynecol Invest 9,313-318.
31. Zhao SZ, Wong JM, Davis MB, Gersh GE and Johnson KE (1998) The cost of inpatient endometriosis treatment: An analysis based on the Healthcare Cost and Utilization Project Nationwide Inpatient Sample. Am J Manag Care 8,1127-1134.