Evidence against α2-adrenoceptors mediating relaxation in rat thoracic aortae: α2-agonists relaxation depends on interaction with α1-adrenoceptors

Fundamental and Clinical Pharmacology

Volumn 20, Issue 4, 2006, Pages 339-349

  Castillo, Enrique F ^a   Ortíz, Cindy S ^a   López, Ruth M ^a   Ruíz, Antonio ^a   Vélez, Juan M ^a   Castillo, Carlos ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

1 adrenoceptors; 2 adrenoceptor agonists; Endothelium; Nitric oxide; Rat aorta

Indexed keywords

8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ACETYLCHOLINE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; AZEPEXOLE; AZEPINE DERIVATIVE; BRIMONIDINE; CALCIMYCIN; CLONIDINE; IMIDAZOLINE DERIVATIVE; METHOXAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; PROSTAGLANDIN F2 ALPHA; RAUWOLSCINE; SEROTONIN; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; NITRIC OXIDE; PIPERAZINE DERIVATIVE; QUINOXALINE DERIVATIVE; VASOCONSTRICTOR AGENT; YOHIMBINE;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; FUNCTIONAL ASSESSMENT; HYPOTHESIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; RAT; THORACIC AORTA; VASCULAR RING; ANIMAL; DOSE RESPONSE; DRUG EFFECT; IN VITRO STUDY; METABOLISM; VASCULAR ENDOTHELIUM; VASODILATATION; WISTAR RAT;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; AORTA, THORACIC; AZEPINES; CLONIDINE; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; MALE; METHOXAMINE; NITRIC OXIDE; PHENYLEPHRINE; PIPERAZINES; QUINOXALINES; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, ALPHA-2; SEROTONIN; VASOCONSTRICTOR AGENTS; VASODILATION; YOHIMBINE;

EID: 33745807644     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2006.00421.x     Document Type: Article

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