Burden of abnormal hematopoietic clone in patients with myelodysplastic syndromes

Chinese Medical Sciences Journal

Volumn 21, Issue 2, 2006, Pages 99-103

  Wang, Hua Quan ^a,b   Shao, Zong Hong ^a,b   Shi, Jun ^a   Cao, Yan Ran ^a   Liu, Hong ^a   Bai, Jie ^a   Tu, Mei Feng ^a   Xing, Li Ming ^a   Cui, Zhen Zhu ^a   Liu, Shi He ^a   Sun, Jun ^a   Jia, Hai Rong ^a   Yang, Tian Ying ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

karyotype; Myelodysplastic syndromes; T lymphocyte

Indexed keywords

HEMOGLOBIN; INTERLEUKIN 2; LACTATE DEHYDROGENASE; TUMOR NECROSIS FACTOR;

ADOLESCENT; ADULT; AGED; ARTICLE; BLAST CELL; BLOOD TRANSFUSION; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CLONE; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE; ERYTHROCYTOSIS; FEMALE; HEMATOPOIESIS; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN CELL; LACTATE DEHYDROGENASE BLOOD LEVEL; LEUKOCYTE COUNT; MALE; MEGAKARYOCYTE; MYELODYSPLASTIC SYNDROME; THROMBOCYTE COUNT;

ADOLESCENT; ADULT; AGED; BONE MARROW CELLS; CASE-CONTROL STUDIES; CHROMOSOME ABERRATIONS; FEMALE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; NEOPLASTIC STEM CELLS; POLYCYTHEMIA; T-LYMPHOCYTE SUBSETS; YOUNG ADULT;

EID: 33745786773     PISSN: 10019294     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Brunning RD, Bennett JM, Flandrin G, et al. Myelodysplastic syndromes. In: Jaffe ES, Harris NL, Stein H, editors. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press; 2001. p. 61-73.
2. List AF, Vardiman J, Issa JP, et al. Myelodysplastic syndromes. Hematology (Am Soc Hematol Educ Program) 2004: 297-317.
3. Sole F, Espinet B, Sanz GF, et al. Incidence, characterization and prognostic signification of chromosomal abnormalities in 640 patients with primary myelodysplastic syndrome. Br J Haematol 2000; 108: 346-56.
4. Jotterand M, Parlier V. Diagnosis and pronostic signification of cytogenetics in adult primary myelodysplastic syndromes. Leuk Lymphoma 1996; 23: 253-66.
5. Shi J, Shao ZH, Chen GB, et al. Clinical and laboratory features of preleukemia patients. Chin J Med 2002; 115: 3-7.
6. List AF, Sandberg AA, Doll DC. Myelodysplastic syndromes. In: Greer JP, Foerster J, Lukens JN, editors. Wintrobe's clinical hematology. 11th ed. Philadelphia; Lippincott Williams & Wilkins Press; 2004. p. 2207-34.
7. Bennett JM. The myelodysplastic syndromes: pathobiology and clinical management. New York: Marcel Dekker Inc; 2002. p. vii-viii.
8. Shao ZH. The pathogenesis of myelodysplastic syndromes. Chin J Hematol 2004; 25: 701-2.
9. Weimar IS, Bourhis JH, De Gast GC, et al. Clonality in myelodysplastic syndromes. Leuk Lymphoma 1994; 13: 215-21.
10. Morel P, Hebbar M, Lai JL, et al. Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: a report on 408 cases. Leukemia 1993; 7: 1315-23.
11. Fernandez TS, Ornellas MH, Carvalho LO, et al. Chromosomal alterations associated with evolution from myelodysplastic syndrome to acute myeloid leukemia. Leuk Res 2000; 24: 839-48.
12. Toyama K, Ohyashiki K, Yoshida Y, et al. Clinical implications of chromosomal abnormalities in 401 patients with myelodysplastic syndromes: a multicentric study in Japan. Leukemia 1993; 7: 499-508.
13. Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997; 89: 2079-88.
14. Schmetzer HM, Poleck B, Duell T, et al. Cytogenetic and Southern blot analysis to demonstrate clonality and to estimate prognosis in patients with myelodysplastic syndromes. Ann Hematol 2000; 79: 20-9.
15. Hughes T, Kaeda J, Branford S, et al. Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia. N Engl J Med 2003; 349: 1423-32.
16. Cheson BD, Bennett JM, Kantarjian H, et al. Report of an international working group to standardize response criteria for myelodysplastic syndromes. Blood 2000; 96: 9671-4.