Chronic PKC-β activation in HT-29 Cl.19a colonocytes prevents cAMP-mediated ion secretion by inhibiting apical membrane current generation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 291, Issue 2, 2006, Pages

  Broughman, James R ^a   Sun, Limin ^a   Umar, Shahid ^a   Scott, Jason ^a   Sellin, Joseph H ^a   Morris, Andrew P ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Cystic fibrosis transmembrance conductance regulator; Phorbol ester; Protein kinase C; Short circuit current

Indexed keywords

12 DEOXYPHORBOL 20 ACETATE 13 PHENYLACETATE; CYCLIC AMP; FORSKOLIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL DERIVATIVE; PROTEIN KINASE C BETA; UNCLASSIFIED DRUG;

APICAL MEMBRANE; ARTICLE; CELL LINE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INCUBATION TIME; PRIORITY JOURNAL;

COLON; CYCLIC AMP; ENZYME ACTIVATION; HT29 CELLS; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; PROTEIN KINASE C;

EID: 33745778679     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00355.2005     Document Type: Article

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