Endothelial dysfunction: Possible mechanisms and ways of correction

Experimental and Clinical Cardiology

Volumn 11, Issue 2, 2006, Pages 107-110

  Sagach, Vadim ^a   Bondarenko, Alexander ^a   Bazilyuk, Olga ^a   Kotsuruba, Anatoliy ^a  

^a BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

Author keywords

Aging; Diabetes; Endothelial dysfunction

Indexed keywords

ACETYLCHOLINE; ARGININE; CITRULLINE; ENALAPRIL; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERY DILATATION; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXPERIMENTAL DIABETES MELLITUS; FEMALE; HYPERPOLARIZATION; MALE; MEMBRANE STEADY POTENTIAL; NONHUMAN; PATCH CLAMP; RAT;

EID: 33745775505     PISSN: 12056626     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (16)

1. Mombouli JV, Vanhoutte PM. Endothelial dysfunction: From physiology to therapy. J Mol Cell Cardiol 1999;31:61-74.
2. Vanhoutte PM. Endothelial dysfunction and atherosclerosis. Eur Heart J 1997;18(Suppl E):E19-E29.
3. Vanhoutte PM. Endothelial dysfunction in hypertension. J Hypertens Suppl 1996;14:S83-S93.
4. Marin J, Redondo J. Vascular sodium pump: Endothelial modulation and alterations in some pathological processes and aging. Pharmacol Ther 1999;84:249-71.
5. 2+ in relation to generation of acetylcholine-induced endothelium-dependent hyperpolarization in rat mesenteric artery. Br J Pharmacol 1997;120:1328-34.
6. Ca channels and elicit EDHF-type arteriolar dilation via gap junctions. Am J Physiol Heart Circ Physiol 2002; 282:H1760-7.
7. Luckhoff A, Busse R. Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential. Pflügers Arch 1990;416:305-11.
8. Goto K, Fujii K, Kansui Y, Iida M. Changes in endothelium-derived hyperpolarizing factor in hypertension and ageing: Response to chronic treatment with renin-angiotensin system inhibitors. Clin Exp Pharmacol Physiol 2004;31:650-5.
9. Fujii K, Ohmori S, Tominaga M, et al. Age-related changes in endothelium-dependent hyperpolarization in the rat mesenteric artery. Am J Physiol 1993;265:H509-16.
10. Pieper GM, Siebeneich W. Temocapril, an angiotensin converting enzyme inhibitor, protects against diabetes-induced endothelial dysfunction. Eur J Pharmacol 2000;403:129-32.
11. 2+-dependent NOS in renal cortex of ANG II-infused hypertensive rats. Am J Physiol 1999;277:F797-804.
12. Feletou M, Vanhoutte PM. EDHF: New therapeutic targets? Pharmacol Res 2004;49:565-80.
13. Matz RL, Andriantsitohaina R. Age-related endothelial dysfunction: Potential implications for pharmacotherapy. Drugs Aging 2003;20:527-50.
14. Baluchnejadmojarad T, Roghani M, Imani A. Protective effect of enalapril on vascular reactivity of the rat aorta. Vascul Pharmacol 2004;40:301-7.
15. Becker RH, Wiemer G, Linz W. Preservation of endothelial function by ramipril in rabbits on a long-term atherogenic diet. J Cardiovasc Pharmacol 1991;18(Suppl 2):110-5.
16. Bennett MA, Thurston H. Effect of angiotensin-converting enzyme inhibitors on resistance artery structure and endothelium-dependent relaxation in two-kidney, one-clip Goldblatt hypertensive and sham-operated rats. Clin Sci (Lond) 1996;90:21-9.