Sustained elevation of dendritic calcium evokes widespread endocannabinoid release and suppression of synapses onto cerebellar purkinje cells

Journal of Neuroscience

Volumn 26, Issue 25, 2006, Pages 6841-6850

  Brenowitz, Stephan D ^a   Best, Aaron R ^a   Regehr, Wade G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calcium; Cerebellum; Endocannabinoids; Purkinje cell; Retrograde inhibition; Synaptic plasticity; Two photon imaging

Indexed keywords

CALCIUM; ENDOCANNABINOID; METABOTROPIC RECEPTOR 1; PHOSPHOLIPASE C; 1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIOXO 6 NITRO 7 SULFAMOYLBENZO(F)QUINOXALINE; 2,3-DIOXO-6-NITRO-7-SULFAMOYLBENZO(F)QUINOXALINE; AMINO ACID RECEPTOR BLOCKING AGENT; ENZYME INHIBITOR; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE; QUINOXALINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DENDRITIC CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; SYNAPTIC MEMBRANE; SYNAPTIC TRANSMISSION; ANIMAL; CELL MEMBRANE POTENTIAL; CEREBELLUM; COMPARATIVE STUDY; CYTOLOGY; DENDRITE; DRUG EFFECT; ELECTROSTIMULATION; IN VITRO STUDY; METABOLISM; METHODOLOGY; NERVE CELL INHIBITION; PATCH CLAMP; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION RESPONSE; SPRAGUE DAWLEY RAT; SYNAPSE; TIME;

ANIMALS; CALCIUM; CEREBELLUM; DENDRITES; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; ENDOCANNABINOIDS; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; MEMBRANE POTENTIALS; NEURAL INHIBITION; PATCH-CLAMP TECHNIQUES; PIPERIDINES; PURKINJE CELLS; PYRAZOLES; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; SYNAPSES; TIME FACTORS;

EID: 33745770697     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1280-06.2006     Document Type: Article

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