Quantification of fudosteine in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry employing precolumn derivatization with 9-fluorenylmethyl chloroformate

Journal of Mass Spectrometry

Volumn 41, Issue 5, 2006, Pages 685-692

  Xu, Fengguo ^a   Zhang, Zunjian ^a   Jiao, Haoyan ^a   Tian, Yuan ^a   Zhang, Beibei ^a   Chen, Yun ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Fudosteine; Human plasma; LC MS; Pharmacokinetics; Precolumn derivatization

Indexed keywords

ASSAYS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETRY; PHARMACOKINETICS; PRECIPITATION (CHEMICAL); PROTEINS;

BORATE BUFFER; FUDOSTEINE; HUMAN PLASMA; PRECOLUMN DERIVATIZATION;

BODY FLUIDS;

9 FLUORENYLMETHYL CHLOROFORMATE; ACETIC ACID ETHYL ESTER; ACETONITRILE; BORIC ACID; BUFFER; FUDOSTEINE;

ACCURACY; ARTICLE; BLOOD SAMPLING; DERIVATIZATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; EVAPORATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRECIPITATION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; VALIDATION STUDY;

ADMINISTRATION, ORAL; BORATES; BUFFERS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTINE; FEMALE; FLUORENES; HUMANS; MALE; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33745769486     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1028     Document Type: Article

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