Synthesis of imidazole based p38 MAP (mitogen-activated protein) kinase inhibitors under buffered conditions

Organic Process Research and Development

Volumn 10, Issue 3, 2006, Pages 556-560

  Magnus, Nicholas A ^a   Diseroad, William D ^a   Nevill Jr , C Richard ^a   Wepsiec, James P ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33745763352     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op060042t     Document Type: Article

References (12)

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2. (b) Adams, J. L.; Badger, A. M.; Kumar, S.; Lee, J. C. p38 Kinase: Molecular target for the inhibition of proinflammatory cytokines. Prog. Med. Chem. 2001, 38, 1.
3. de Dios, A.; Shih, C.; de Uralde, B. L.; Sánchez, C.; del Prado, M.; Cabrejas, L. M. M.; Pleite, S.; Blanco-Urgoiti, J.; Lorite, M. C.; Nevill, R. C., Jr.; Bonjouklian, R.; York, J.; Vieth, M.; Wang, Y.; Magnus, N. A.; Campbell, R. M.; Anderson, B. D.; McCann, D. J.; Giera, D. D.; Lee, P. A.; Schultz, R. M.; Li, L. C.; Johnson, L. M.; Wolos, J. A. J. Med. Chem. 2005, 48, 2270 and references therein.
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