Scavenging of free radicals and the late toxicity of radiochemotherapy in head and neck cancer patients

Trace Elements and Electrolytes

Volumn 23, Issue 3, 2006, Pages 181-185

  Buntzel J ^a   Glatzel, M ^a   Mucke R ^a   Bruns, F ^a   Kisters, K ^a   Micke, O ^a  

^a Zentralklinikum Suhl ^*

Author keywords

Amifostine; Free radical; Head and neck cancer; Radioprotector; Savengers (SFR); Toxicity

Indexed keywords

AMIFOSTINE; FREE RADICAL;

ADULT; AGED; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DYSPHAGIA; ESOPHAGUS STENOSIS; FEMALE; FOLLOW UP; HEAD AND NECK CANCER; HUMAN; LYMPHEDEMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TASTE DISORDER; TOXICITY; XEROSTOMIA;

EID: 33745744531     PISSN: 09462104     EISSN: None     Source Type: Journal    
DOI: 10.5414/tep23181     Document Type: Article

References (10)

1. Antonadou D, Pepelassi M, Synodinou M, Puglisi M, Throuvalas N. Prophylactic use of amifostine to prevent radiochemotherapy-induced mucositis and xerostomia in head and neck cancer. Int J Radiat Oncol Biol Phys. 2000; 52: 739-747.
2. Brizel D., Wasserman TH, Henke M, Strnad V, Rudat V, Monnier A, Eschwege F, Zhang J, Russell L, Oster O, Sauer R. Phase III randomized trial of amifostine as a radioprotector in head and neck cancer. J Clin Oncol. 2000; 18: 3339-3345.
3. Büntzel J, Küttner K, Fröhlich D, Glatzel M. Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer. Ann Oncol. 1998; 9: 505-509.
4. Büntzel J, Glatzel M, Küttner K, Weinaug R, Fröhlich D. Amifostine in simultaneous radiochemotherapy of advanced head and neck cancer. Semin Radiat Oncol. 2002a; 12 (Suppl 1): 4-13.
5. Büntzel J, Weinaug R, Glatzel M, Fröhlich D, Micke O, Schüller P, Küttner K. Sodium selenite in the treatment of interstitial post-irradiation edema of the head and neck area. Trace Elem Electrolytes. 2002b; 19: 33-37.
6. Büntzel J, Micke O, Mücke R, Glatzel M, Schönekaes KG, Schäfer U, Kisters K, Bruns F. Amifostine and selenium during simultaneous radiochemotherapy in head and neck cancer - redox status data. Trace Elem Electrolytes. 2005; 22: 211-215.
7. Büntzel J, Micke O, Adamietz IA, Monnier A, Glatzel M, de Vries A. Intravenous amifostine during chemoradiotherapy for head-and-neck cancer. A randomized placebo-controlled phase III study. Int J Radiat Oncol Biol Phys. 2006; 64: 684-691.
8. Capizzi RL, Oster W. Protection of normal tissue from cytotoxic effects of chemotherapy and radiation by amifostine: clinical experiences. Eur J Cancer. 1995; 31A: 8-13.
9. Micke O, Bruns F, Mücke R, Schäfer V, Glatzel M, de Vries A, Schönekaes K, Kisters K, Büntzel J. Selenium in the treatment of radiation-associated secondary lymphedema. Int J Radiat Oncol Biol Phys. 2003; 56: 40-49.
10. Schüller P, Püttmann S, Mücke R, Senner V, Schäfer U, Kisters K, Micke O. From the radiolysis of water to the role of trace elements in radiobiology and clinical radiation therapy: following a logical chain. Trace Elem Electrolytes. 2001; 18: 186-192.