Concentration of 6-aminopenicillanic acid from penicillin bioconversion solution and its mother liquor by nanofiltration membrane

Biotechnology and Bioprocess Engineering

Volumn 6, Issue 3, 2001, Pages 200-204

  Cao, Xuejun ^a   Wu, Xing Yan ^a   Wu, Tong ^b   Jin, Keming ^b   Hur, Byung Ki ^c  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Millipore China Coporation Limited   (China)

^c Inha University   (South Korea)

Author keywords

6 APA; Crystallization; Mother liquor; Nanofiltration

Indexed keywords

EID: 33745741351     PISSN: 12268372     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02932551     Document Type: Article

References (9)

1. Schaep, J., B. V. D. Bruggen, C. Vandecasteele, and D. Wilms (1998) Influence of ion size and charge in nanofiltration. Separation Purify. Technol. 14: 155-162.
2. Wang, X. L., T. Tsuru, S. I. Nakao, and S. Kimura (1997) The electrostatic and steric-hindrance model for the transport of charged solutes through nanofiltration membranes. J. Membrane Sci. 135: 19-32.
3. Freger, V., T. C. Arnot, and J. A. Howell (2000) Separation of concentrated organic/inorganic salt mixtures by nanofiltration. J. Membrane Sci. 178: 185-193.
4. van der Horst, H. C., J. M. K. Timmer, T. Robbertsen, and J. Leenders (1995) Use of nanofiltration for concentration and dermineralization in the dairy industry: Model for mass transport. J. Membrane Sci. 104: 205-218.
5. Danzig, J., W. Tischer, and C. Wandrey (1995) Continuous enzyme-catalyzed production of 6-aminopenicillanic acid and product concentration by reverse osmosis. Chem. Eng. Technol. 18: 256-259.
6. Chen, J. H. and L. D. Xu (1990) Industrial analysis of antibiotics, p. 271. Chinese Medicinal Science and Technology Publisher, Beijing, China.
7. Spiegler, K. S. and O. Kedem (1966) Termodynamics of hyperfiltration (reverse osmosis): Criteria for efficient membranes. Desalination 1: 311-326.
8. Hoffer, E. and O. Kedem (1967) Hyperfiltration in charged membranes: The fixed charge model. Desalination 2: 25-32.
9. Hoffer, E. and O. Kedem (1972) Ion separation by hyperfiltration througy charged membranes: Calculation based on TMS model. Ind. Eng. Chem. Process Des. Develop. 11: 221-225.