An operant determination of the behavioral mechanism of benzodiazepine enhancement of food intake

Psychopharmacology

Volumn 187, Issue 2, 2006, Pages 138-142

  O'Hare, E ^a   Kim, E M ^a   Tierney, K J ^b  

^a UNIVERSITY OF ULSTER   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Barbiturates; Benzodiazepines; Cyclic ratio; Palatability; Picrotoxin

Indexed keywords

BENZODIAZEPINE; CHLORDIAZEPOXIDE; PENTOBARBITAL; PICROTOXIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DECREASED APPETITE; DRUG EFFECT; DRUG MECHANISM; FOOD INTAKE; INCREASED APPETITE; INSTRUMENTAL CONDITIONING; MALE; NONHUMAN; PALATABILITY; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM;

ANIMALS; BENZODIAZEPINES; CHLORDIAZEPOXIDE; CONDITIONING, OPERANT; EATING; MALE; MOTIVATION; PENTOBARBITAL; PICROTOXIN; RATS; RATS, WISTAR; REINFORCEMENT SCHEDULE; TASTE;

EID: 33745736005     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-006-0412-5     Document Type: Article

References (43)

1. Anderson-Baker WC, McLaughlin CL, Baile CA (1979) Oral and hypothalamic injections of barbiturates, benzodiazepines and cannabinoids and food intake in rats. Pharmacol Biochem Behav 11:487-491
2. Berridge KC, Pecina S (1995) Benzodiazepines, appetite, and taste palatability. Neurosci Biobehav Rev 19:121-131
3. Berridge KC, Treit D (1986) Chlordiazepoxide directly enhances positive ingestive reactions in the rat. Pharmacol Biochem Behav 24:217-221
4. Cole SO (1983) Combined effects of chlordiazepoxide treatment and food deprivation on concurrent measures of feeding and activity. Pharmacol Biochem Behav 18:369-372
5. Cooper SJ (2004) Endocannabinoids and food consumption: comparisons with benzodiazepine and opioid palatability-dependant appetite. Eur J Pharmacol 500:37-49
6. Cooper SJ (2005) Palatability dependant appetite and benzodiazepines: new directions from the pharmacology of GABA(A) receptor subtypes. Appetite 44:133-150
7. Cooper SJ, Estall LB (1985) Behavioral pharmacology of food, water and salt intake in relation to drug actions at benzodiazepine receptors. Neurosci Biobehav Rev 9:5-19
8. Cooper SJ, Yearbury RE (1988) Clonazepam selectively increases saccharin ingestion in two-choice test. Brain Res 456:173-176
9. Ettinger RH, Staddon JER (1982) Decreased feeding associated with acute hypoxia in rats. Physiol Behav 29:455-458
10. Ettinger RH, Staddon JER (1983) Operant regulation of feeding: a static analysis. Behav Neurosci 97:639-653
11. Ettinger RH, Thompson S, Staddon JER (1986) Cholecystokinin, diet palatability, and feeding regulation in rats. Physiol Behav 36:801-809
12. Foltin RW, Ellis S, Schuster CR (1985) Specific antagonism by Ro 15-1788 of benzodiazepine-induced increases in food intake in rhesus monkeys. Pharmacol Biochem Behav 23:249-253
13. Gray RW, Cooper SJ (1995) Benzodiazepines and palatability: taste reactivity in normal ingestion. Physiol Behav 58:853-859
14. Grill HJ, Norgren R (1978) The taste-reactivity test: I. Mimetic response to gustatory stimuli in neurologically normal rats. Brain Res Bull 143:263-279
15. Higgs S, Cooper SJ (1995) Benzodiazepine receptor inverse agonists and ingestive behavior: the palatability hypothesis. In: Sarter M, Nutt DJ, Lister RG (eds) Benzodiazepine receptor inverse agonists. Wiley-Liss, New York, pp 163-184
16. Higgs S, Cooper SJ (1996) Effects of the benzodiazepine receptor agonist Ro15-4513 on the ingestion of sucrose and sodium saccharin solutions: a microstructural analysis of licking behavior. Behav Neurosci 110:559-566
17. Higgs S, Cooper SJ (2000) The effect of the dopamine D2 receptor antagonist raclopride on the pattern of licking microstructure induced by midazolam in the rat. Eur J Pharmacol 409:73-80
18. Johnson DN (1978) Effect of diazepam on food consumption in rats. Psychopharmacology 56:111-112
19. Kelly J, Grossman SP (1979) GABA and hypothalamic feeding systems. II. A comparison of GABA, glycine and acetylcholine agonists and their antagonists. Pharmacol Biochem Behav 11:647-652
20. Kelly J, Grossman SP (1980) GABA and hypothalamic feeding systems. Brain Res Bull 5:237-244
21. Leander JD (1983) Effects of punishment-attenuating drugs on deprivation-induced drinking: implications for conflict procedures. Drug Dev Res 3:185-191
22. Martin JR, Schock P, Jenck F, Moreau JL, Haefely WE (1993) Pharmacological characterization of benzodiazepine receptor ligands with intrinsic efficacies ranging from high to zero. Psychopharmacology 111:415-422
23. Meddis R (1975) A simple two-group test for matched scores with unequal cell frequencies. Br J Psychol 66:225-227
24. Naruse T, Asami T, Koizumi Y (1988) Effects of naloxone and picrotoxin on diazepam- or pentobarbital-induced hyperphagia in nondeprived rats. Pharmacol Biochem Behav 31:709-711
25. O'Hare E, Tierney KJ, Shephard RA (1991) Cyclic-ratio schedule analysis of a serotonin agonist and depletor on consummatory behaviour. Physiol Behav 29:331-334
26. O'Hare E, Levine AS, Semotuk MT, Tierney KJ, Shephard RA, Grace MK, Cleary J (1996) Utilization of a novel model of food reinforced behavior involving neuropeptide-Y, insulin, 2-deoxy-D-glucose and naloxone. Behav Pharmacol 7:742-753
27. Page EB (1963) Ordered hypothesis for multiple treatments: a significance test for linear ranks. J Am Stat Assoc 58:216-230
28. Parker LA (1995) Chlordiazepoxide enhances the palatability of lithium-amphetamine, and saline-paired saccharin solution. Pharmacol Biochem Behav 50:345-349
29. Paul V, Ekambaram P (2005) Effects of sodium nitroprusside, a nitric oxide donor, on gamma-aminobutyric acis concentration in the brain and on picrotoxin-induced convulsions in combination with phenobarbitone in rats. Pharmacol Biochem Behav 80:363-370
30. Posadas-Andrews A, Burton MJ, Cooper SJ (1985) Chlordiazepoxide and food-depravation compared using a food-preference test in the rat. Rev Mex Anal Conducta 11:21-30
31. Poschel BPH (1971) A simple and specific screen for benzodiazepine-like drugs. Psychopharmacology 19:193-198
32. Randall LO (1960) Pharmacology of methaminodiazepoxide. Dis Nerv Syst 21:7-10
33. Randall LO, Schallek W, Heise GA, Keith EF, Bagdon RE (1960) The psychosedative properties of methaminodiazepoxide. J Pharmacol Exp Ther 129:163-171
34. Seoane JR, Baile CA (1973) Feeding behaviour in sheep as related to the hypnotic activities of barbiturates injected into the third ventricle. Pharmacol Biochem Behav 1:47-53
35. Shephard RA (1987) Behavioral effects of GABA agonists in relation to anxiety and benzodiazepine actions. Life Sci 40:2429-2436
36. Shephard RA, Broadhurst PL (1982) Effects of diazepam and picrotoxin on hyperphagia in rats. Neuropharmacology 21:771-773
37. Shephard RA, Estall LB (1984) Anxiolytic actions of chlordiazepixidedetermine effects on hyponeophagia in rats. Psychopharmacology 82:343-347
38. Shephard RA, Hamilton MS (1989) Chlordiazepoxide and valproate enhancement of saline drinking by nondeprived rats: effects of bicuculline, picrotoxin and Ro 15-1788. Pharmacol Biochem Behav 33:285-290
39. Treit D, Berridge KC (1990) A comparison of benzodiazepine, serotonin, and dopamine agents in the taste-reactivity paradigm. Pharmacol Biochem Behav 37:451-456
40. Treit D, Berridge KC, Schultz CE (1987) The direct enhancement of positive palatability by chlordiazepoxide is antagonized by Ro15-1788 and CGS 8216. Pharmacol Biochem Behav 26:709-714
41. Tye NC, Nicholas DJ, Morgan MJ (1975) Chlordiazepoxide and preference for free food in rats. Pharmacol Biochem Behav 3:1149-1151
42. Wise RA, Dawson V (1974) Diazepam-induced eating and lever-pressing for food in sated rats. J Comp Physiol Psychol 86: 930-941
43. Yerbury RE, Cooper SJ (1987) The benzodiazepine partial agonist, Ro16-6028 and Ro17-1812, increase palatable food consumption in nondeprived rats. Pharmacol Biochem Behav 28:427-431