Possibility of conditioning predamaged grafts after cold storage: Influences of oxygen and nutritive stimulation

Transplant International

Volumn 19, Issue 8, 2006, Pages 667-674

  Manekeller, Steffen ^a,b   Minor, Thomas ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Apoptosis; Endoplasmic reticulum; Endoplasmic stress; Machine perfusion; Oxygen; Preservation; Resuscitation; Substrate; Transplantation

Indexed keywords

ADENOSINE; ALANINE AMINOTRANSFERASE; CASPASE 12; CASPASE 3; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HTK SOLUTION; OXYGEN; PHOSPHATE; PRESERVATION SOLUTION; UNCLASSIFIED DRUG; WILLIAMS E SOLUTION;

ANIMAL TISSUE; ARTICLE; BILE; BILE SECRETION; CONTROLLED STUDY; CRYOPRESERVATION; GRAFT DYSFUNCTION; GRAFT PRESERVATION; HEAT; LIVER GRAFT; LIVER INJURY; LIVER METABOLISM; LIVER PARENCHYMA; LIVER PRESERVATION; MALE; NONHUMAN; NUTRIENT SOLUTION; OXYGENATION; PERFUSION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; RAT STRAIN;

ANIMALS; BASE SEQUENCE; CASPASE 12; CASPASE 3; CASPASES; COLD; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; LIVER; LIVER TRANSPLANTATION; MALE; MOLECULAR CHAPERONES; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; OXYGEN; RATS; RATS, WISTAR; RNA, MESSENGER; TRANSCRIPTION FACTOR CHOP;

EID: 33745727559     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2006.00320.x     Document Type: Article

References (39)

1. Wijnen RMH, Booster MH, Stubenitsky BM, de Boer J, Heinemann E, Kootstra G. Outcome of transplantation of non-heart-beating donor kidneys. Lancet 1995; 345: 1067.
2. D'Alessandro AM, Hoffmann RM, Knechtle SJ, et al. Liver transplantation from controlled non-heart-beating donors. Surgery 2000; 128: 579.
3. St Peter SD, Imber CJ, Friend PJ. Liver and kidney preservation by perfusion. Lancet 2002; 359: 604.
4. Minor T, Isselhard W. Synthesis of high energy phosphates during cold ischemic rat liver preservation with gaseous oxygen insufflation. Transplantation 1996; 61: 20.
5. Schön MR, Hunt CJ, Pegg DE, Wight DG. The possibility of resuscitating livers after warm ischemic injury. Transplantation 1993; 56: 24.
6. Minor T, Saad S, Nagelschmidt M, et al. Successful transplantation of porcine livers after warm ischemic insult in situ and cold preservation including postconditioning with gaseous oxygen. Transplantation 1998; 65: 1262.
7. Schön MR, Schrem H, Lemmens HP, Wolf S, Neuhaus P. Erfolgreiche Transplantation von Lebern nicht herzschlagender Spender nach normothermer extrakorporaler Leberperfusion im Schweinemodell. Langenbecks Arch Chir Suppl Kongressbd 1997; 114: 725.
8. Minor T, Klauke H, Vollmar B, Isselhard W, Menger MD. Biophysical aspects of liver aeration by vascular persufflation with gaseous oxygen. Transplantation 1997; 63: 1843.
9. Palombo JD, Bowers JL, Clouse ME, McCullough A, Forse RA, Bistrian BR. Hepatic utilisation of exogenous nucleotide precursors for restoration of ATP after cold ischemia in rats. Am J Clin Nutr 1993; 57: 420.
10. Calmus Y, Cynober L, Dousset B, et al. Evidence for the detrimental role of proteolysis during liver preservation in humans. Gastroenterology 1995; 108: 1510.
11. Minor T, Klauke H, Nagelschmidt M, Isselhard W. Reduction of proteolysis by venous-systemic oxygen persufflation during rat liver preservation and improved functional outcome after transplantation. Transplantation 1997; 63: 365.
12. Pokorny H, Rasoul-Rockenschaub S, Langer F, et al. Histidine-tryptophan- ketoglutarate solution for organ preservation in human liver transplantation-a prospective multi-centre observation study. Transplant Int 2004; 17: 256.
13. Minor T, Akbar S, Tolba R, Dombrowski F. Cold preservation of fatty liver grafts: prevention of functional and ultrastructural impairments by venous oxygen persufflation. J Hepatol 2000; 32: 105.
14. Minor T, Yamaguchi T, Isselhard W. Effects of taurine on liver preservation in UW solution with consecutive rewarming in the isolated perfused rat liver. Transplant Int 1995; 8: 174.
15. Minor T, Kötting M. Gaseous oxygen for hypothermic preservation of predamaged liver grafts: fuel to cellular homeostasis or radical tissue alteration? Cryobiology 2000; 40: 182.
16. Manekeller S, Sioutis M, Minor T. Time and temperature of oxygenated machine perfusion preservation as determinants for ulterior recovery of marginal donor livers. European Surgical Research 2005; 37(Suppl. 1): 3.
17. Emadali A, Nguyen DT, Rochon C, Tzimas GN, Metrakos PP, Chevet E. Distinct endoplasmic reticulum stress responses are triggered during human liver transplantation. J Pathol 2005; 207: 111.
18. Minor T, Manekeller S, Sioutis M, Dombrowski F. Endoplasmic and vascular surface activation during organ preservation: refining upon the benefits of machine perfusion. Am J Transplant 2006; 6: 1355.
19. Jayanthi S, Deng X, Noailles PA, Ladenheim B, Cadet JL. Methamphetamine induces neuronal apoptosis via crosstalks between endoplasmic reticulum and mitochondria-dependent death cascades. FASEB J 2004; 18: 238.
20. Hitomi J, Katayama T, Taniguchi M, Honda A, Imaizumi K, Tohyama M. Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12. Neurosci Lett 2004; 357: 127.
21. Busza AL, Fuller BJ, Proctor E. Evaluation of cold reperfusion as an indicator of viability in stored organs: a 31P NMR study in rat liver. Cryobiology 1994; 31: 26.
22. Vajdova K, Smrekova R, Mislanova C, Kukan M, Lutterova M. Cold-preservation-induced sensitivity of rat hepatocyte function to rewarming injury and its prevention by short-term reperfusion. Hepatology 2000; 32: 289.
23. Minor T, Saad S, Kötting M, Nagelschmidt M, Paul A. Endischemic oxygen persufflation to improve viability of marginally preserved donor livers. Transplant Int 1998; 11: S400.
24. Vajdova K, Graf R, Clavien PA. ATP-supplies in the cold-preserved liver: a long-neglected factor of organ viability. Hepatology 2002; 36: 1543.
25. Harvey PRC, Iu S, McKeown CMB, Petrunka CN, Ilson RG, Strasberg SM. Adenine nucleotide tissue concentrations and liver allograft viability after cold preservation and warm ischemia. Transplantation 1988; 45: 1016.
26. Kamiike W, Burdelski M, Steinhoff G, Ringe B, Lauchart W, Pichlmayr R. Adenine nucleotide metabolism and its relation to organ viability in human liver transplantation. Transplantation 1988; 45: 138.
27. Hölscher M, Groenewoud AF. Current status of the HTK solution of Bretschneider in organ preservation. Transplant Proc 1991; 23: 2334.
28. Lockett CJ, Fuller BJ, Busza AL, Proctor E. Hypothermic perfusion preservation of liver: the role of phosphate in stimulating ATP synthesis studied by 31P NMR. Transplant Int 1995; 8: 440.
29. Kötting M, Minor T. Biochemical effects and cyclic-amp second messenger signal upon venous oxygen persufflation of ischemically preserved livers. Transplant Proc 2000; 32: 11.
30. Minor T, Saad S, Kötting M, Nagelschmidt M, Isselhard W. Short term restoration by gaseous oxygen for long term preservation of predamaged livers from non heart beating donors. Transplant Proc 1997; 29: 3474.
31. Olschewski P, Dombrowski F, Tolba R, Schulz S, Minor T. On the possible impact of the flushout solution in conditioning livers from non-heartbeating donors during preservation by gaseous oxygen. Transplantation Proceedings 2004; 36: 1931.
32. Minor T, Akbar S. Enhancement of endogenous cyclic AMP signal: a new approach to allow for cold preservation of rat livers from non-heart-beating donors? Transplantation 1998; 66: 990.
33. Mitchell SJ, Churchill TA, Winslet MC, Fuller BJ. Energy metabolism following prolonged hepatic cold preservation: benefits of interrupted hypoxia on the adenine nucleotide pool in rat liver. Cryobiology 1999; 39: 130.
34. Isselhard W, Minor T. Gasförmiger Sauerstoff zur Protektion und Konditionierung von Organen in Ischämie. Zentralbl Chir 1999; 124: 252.
35. Vilatoba M, Eckstein C, Bilbao G, et al. Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis. Surgery 2005; 138: 342.
36. Nakagawa T, Zhu H, Morishima N, et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000; 403: 98.
37. Schildberg FA, Schulz S, Dombrowski F, Minor T. Cyclic AMP alleviates endoplasmic stress and programmed cell death induced by LPS in human. Cell Tissue Res 2005; 320: 91.
38. Zinszner H, Kuroda M, Wang X, et al. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 1998; 12: 982.
39. Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004; 11: 381.