Efficacy and mechanism of adenovirus-mediated VEGF-165 gene therapy for augmentation of skin flap viability

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 1, 2006, Pages

  Huang, Ning ^a   Khan, Asim ^a,b   Ashrafpour, Homa ^a   Neligan, Peter C ^a,b   Forrest, Christopher R ^a,b   Kontos, Christopher D ^c   Pang, Cho Y ^a,b,d  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Capillary density; Nitric oxide; Skin blood flow; Subdermal gene transfer; Vasodilation

Indexed keywords

ADENOVIRUS VECTOR; INDOMETACIN; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; VASCULOTROPIN 165;

ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW; CAPILLARY DENSITY; CELL VIABILITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; GENE THERAPY; MALE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKIN FLAP; UPREGULATION;

ADENOVIRIDAE; ANIMALS; COMBINED MODALITY THERAPY; GENE THERAPY; ISCHEMIA; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN TRANSPLANTATION; SURGICAL FLAPS; TISSUE CULTURE TECHNIQUES; TISSUE SURVIVAL; TRANSFECTION; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33745712688     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01253.2005     Document Type: Article

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