Screening for β-thalassaemia trait in anaemic pregnant women

Gynecologic and Obstetric Investigation

Volumn 62, Issue 1, 2006, Pages 20-27

  Bencaiova, Gabriela ^a,b   Burkhardt, Tilo ^a   Krafft, Alexander ^a   Zimmermann, Roland ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Thalassaemia trait; Anaemia; Haemoglobinopathy; Screening; Thalassaemia

Indexed keywords

HEMOGLOBIN A2; IRON;

ADULT; ARTICLE; BETA THALASSEMIA; CALCULATION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; IRON BLOOD LEVEL; IRON DEFICIENCY ANEMIA; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MICROCYTOSIS; PREGNANCY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SCREENING TEST; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL; YOUDEN INDEX;

ANEMIA, IRON-DEFICIENCY; BETA-THALASSEMIA; ERYTHROCYTE COUNT; ERYTHROCYTE INDICES; FEMALE; HEMOGLOBIN A2; HEMOGLOBINOPATHIES; HUMANS; LIKELIHOOD FUNCTIONS; MASS SCREENING; PREGNANCY; RETROSPECTIVE STUDIES; ROC CURVE; SENSITIVITY AND SPECIFICITY; SWITZERLAND;

EID: 33745699904     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000091813     Document Type: Article

References (17)

1. 2 levels. Haematologica 2003;88:631-636.
2. Law HY, Chee MK, Tan GP, Ng IS: The simultaneous presence of α- and β-thalassaemia alleles: a pitfall of thalassaemia screening. Community Genet 2003;6:14-21.
3. Lemsaddek W, Picanco I, Seuanes F, et al: Spectrum of β-thalassemia mutations and HbF levels in the heterozygous Moroccan population. Am J Hematol 2003;73:161-168.
4. Working Party of the General Haematology Task Force of the British Committee for Standards in Haematology: The laboratory diagnosis of haemoglobinopathies. Br J Haematol 1998;101:783-792.
5. Panyasai S, Sringam P, Fucharoen G, Sanchaisuriya K, Fucharoen S: A simplified screening for α-thalassemia 1 (SEA type) using a combination of a modified osmotic fragility test and a direct PCR on whole blood cell lysates. Acta Haematol 2002;108:74-78.
6. Wanapirak C, Tongsong T, Sirivatanapa P, Sanguansermsri T, Sekararithi R, Tuggapichitti A: Prenatal strategies for reducing severe thalassemia in pregnancy. Int J Gynaecol Obstet 1998;60:239-244.
7. Breymann C, Fibach E, Visca E, Huettner C, Huch A, Huch R: Induction of fetal hemoglobin synthesis with recombinant human erythropoietin in anemic patients with heterozygous β-thalassemia during pregnancy. J Matern Fetal Med 1999;8:1-7.
8. CDC criteria for anemia in children and child-bearing-aged women. MMWR Morb Mortal Wkly Rep 1989;38:400-404.
9. Demir A, Yarali N, Fisgin T, Duru F, Kara A: Most reliable indices in differentiation between thalassemia trait and iron deficiency anemia. Pediatr Int 2002;44:612-616.
10. Jayabose S, Giamelli J, LevondogluTugal O, Sandoval C, Ozkaynak F, Visintainer P: Differentiating iron deficiency anemia from thalassemia minor by using an RDW-based index. J Pediatr Hematol Oncol 1999;21:314.
11. Eldibany MM, Totonchi KF, Joseph NJ, Rhone D: Usefulness of certain red blood cell indices in diagnosing and differentiating thalassemia trait from iron-deficiency anemia. Am J Clin Pathol 1999;111:676-682.
12. Hickman M, Modell B, Greengross P, et al: Mapping the prevalence of sickle cell and β-thalassaemia in England: estimating and validating ethnic-specific rates. Br J Haematol 1999;104:860-867.
13. Rogers M, Phelan L, Bain B: Screening criteria for β-thalassaemia trait in pregnant women. J Clin Pathol 1995;48:1054-1056.
14. Cao A, Rosatelli MC: Screening and prenatal diagnosis of the haemoglobinopathies. Baillieres Clin Haematol 1993;6:263-286.
15. Bain BJ: Screening of antenatal patients in a multiethnic community for β-thalassaemia trait. J Clin Pathol 1988;41:481-485.
16. Liu TC, Seong PS, Lin TK: The erythrocyte cell hemoglobin distribution width segregates thalassemia traits from other nonthalassemic conditions with microcytosis. Am J Clin Pathol 1997;107:601-607.
17. Aslan D, Gumruk F, Gurgey A, Altay C: Importance of RDW value in differential diagnosis of hypochrome anemias. Am J Hematol 2002;69:31-33.