Role of cGMP in sildenafil-induced activation of endothelial Ca(2+)-activated K(+) channels

Journal of Cardiovascular Pharmacology

Volumn 47, Issue 3, 2006, Pages 365-370

  Luedders, Doerte Wiebke ^a   Muenz, Benedikt Manuel ^a   Li, Fang ^a   Rueckleben, Sebastian ^a   Tillmanns, Harald ^a   Waldecker, Bernd ^a   Wiecha, Johannes ^a   Erdogan, Ali ^a   Schaefer, Christian Alexander ^a   Wolfram Kuhlmann, Christoph Ruediger ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

cGMP; Endothelial cells; K+ channel; Protein kinase G; Sildenafil

Indexed keywords

8 BROMO CYCLIC GMP; CALCIUM CHANNEL; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DERIVATIVE; FLUORESCENT DYE; FURA 2; IBERIOTOXIN; POTASSIUM CHANNEL; SILDENAFIL; CALCIUM; CALCIUM ACTIVATED POTASSIUM CHANNEL; CGMP BINDING, CGMP SPECIFIC 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CGMP-BINDING, CGMP-SPECIFIC 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CYCLIC GMP PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PIPERAZINE DERIVATIVE;

ANALYSIS; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CELL FUNCTION; CELL MEMBRANE POTENTIAL; CELL POLARITY; CONCENTRATION RESPONSE; CONDUCTANCE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; FLUORESCENCE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; PATCH CLAMP; PERFUSION; PRIORITY JOURNAL; PROBABILITY; PROTEIN FUNCTION; REGULATORY MECHANISM; UMBILICAL VEIN; UPREGULATION; VASCULAR ENDOTHELIUM; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; CALCIUM; CELLS, CULTURED; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENDOTHELIAL CELLS; HUMANS; MEMBRANE POTENTIALS; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED;

EID: 33745699568     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fjc.0000206438.35477.f2     Document Type: Article

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