Serotonin-3 receptors in gastric mechanisms of cholecystokinin-induced satiety

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 291, Issue 1, 2006, Pages

  Aja, Susan ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ A RECEPTOR ANTAGONIST; LORGLUMIDE; ONDANSETRON; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR;

DRUG ANTAGONISM; DRUG INHIBITION; DRUG MECHANISM; DRUG MIXTURE; DRUG POTENTIATION; EDITORIAL; FOOD INTAKE; GASTROINTESTINAL TRACT FUNCTION; HYPOPHAGIA; INTESTINE FUNCTION; NONHUMAN; PRIORITY JOURNAL; PYLORUS; SATIETY; STOMACH EMPTYING;

ANIMALS; CHOLAGOGUES AND CHOLERETICS; CHOLECYSTOKININ; FEEDING BEHAVIOR; HUNGER; MALE; ONDANSETRON; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN, 5-HT3; SATIETY RESPONSE; SEROTONIN ANTAGONISTS; STOMACH; SUCROSE;

EID: 33745684299     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00159.2006     Document Type: Editorial

References (33)

1. A and 5-HT3 receptors interact in anorectic responses to amino acid deficiency. Pharmacol Biochem Behav 62: 487-491, 1999.
2. Asin KE, Bednarz L, Nikkel AL, Gore PA Jr, and Nadzan AM. A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey. Pharmacol Biochem Behav 42: 699-704, 1992.
3. Bi S and Moran TH. Response to acute food deprivation in OLETF rats lacking CCK-A receptors. Physiol Behav 79: 655-661, 2003.
4. Burton-Freeman B, Gietzen DW, and Schneeman BO. Cholecystokinin and serotonin receptors in the regulation of fat-induced satiety in rats. Am J Physiol Regul Integr Comp Physiol 276: R429-R434, 1999.
5. Cooper SJ and Dourish CT. Multiple cholecystokinin (CCK) receptors and CCK-monoamine interactions are instrumental in the control of feeding. Physiol Behav 48: 849-857, 1990.
6. Cooper SJ, Dourish CT, and Clifton PG. CCK antagonists and CCK-monoamine interactions in the control of satiety. Am J Clin Nutr 55, Suppl 1: 291S-295S, 1992.
7. Cooper SJ, Greenwood SE, and Gilbert DB. The selective 5-HT3 receptor antagonist, ondansetron, augments the anorectic effect of D-amphetamine in nondeprived rats. Pharmacol Biochem Behav 45: 589-592, 1993.
8. Daughters RS, Hofbauer RD, Grossman AW, Marshall AM, Brown EM, Hartman BK, and Faris PL. Ondansetron attenuates CCK induced satiety and c-fos labeling in the dorsal medulla. Peptides 22: 1331-1338, 2001.
9. Devlin MJ, Walsh BT, Guss JL, Kissileff HR, Liddle RA, and Petkova E. Postprandial cholecystokinin release and gastric emptying in patients with bulimia nervosa. Am J Clin Nutr 65: 114-120, 1997.
10. Faris PL, Kim SW, Meller WH, Goodale RL, Oakman SA, Hofbauer RD, Marshall AM, Daughters RS, Banerjee-Stevens D, Eckert ED, and Hartman BK. Effect of decreasing afferent vagal activity with ondansetron on symptoms of bulimia nervosa: a randomised, double-blind trial. Lancet 355: 792-797, 2000.
11. Fletcher PJ and Burton MJ. Microstructural analysis of the anorectic action of peripherally administered 5-HT. Pharmacol Biochem Behav 24: 1133-1136, 1986.
12. Geracioti TD Jr and Liddle RA. Impaired cholecystokinin secretion in bulimia nervosa. N Engl J Med 319: 683-688, 1988.
13. Gershon MD. Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther 13, Suppl 2: 15-30, 1999.
14. Gibbs J, Young RC, and Smith GP. Cholecystokinin decreases food intake in rats. J Comp Physiol Psychol 84: 488-495, 1973.
15. Hammer VA, Gietzen DW, Beverly JL, and Rogers QR. Serotonin3 receptor antagonists block anorectic responses to amino acid imbalance. Am J Physiol Regul Integr Comp Physiol 259: R627-R636, 1990.
16. Hayes MR, Chory FM, Gallagher CA, and Covasa M. Serotonin type-3 receptors mediate cholecystokinin-induced satiation through gastric distension. Am J Physiol Regul Integr Comp Physiol 291: R115-R123, 2006.
17. Hayes MR and Covasa M. CCK and 5-HT act synergistically to suppress food intake through simultaneous activation of CCK-1 and 5-HT3 receptors. Peptides 26: 2322-2330, 2005.
18. Hayes MR, Moore RL, Shah SM, and Covasa M. 5-HT3 receptors participate in CCK-induced suppression of food intake by delaying gastric emptying. Am J Physiol Regul Integr Comp Physiol 287: R817-R823, 2004.
19. Hayes MR, Savastano DM, and Covasa M. Cholecystokinin-induced satiety is mediated through interdependent cooperation of CCK-A and 5-HT3 receptors. Physiol Behav 82: 663-669, 2004.
20. Jiang JC and Gietzen DW. Anorectic response to amino acid imbalance: a selective serotonin3 effect? Pharmacol Biochem Behav 47: 59-63, 1994.
21. Li Y, Hao Y, Zhu J, and Owyang C. Serotonin released from intestinal enterochromaffin cells mediates luminal non-cholecystokinin-stimulated pancreatic secretion in rats. Gastroenterology 118: 1197-1207, 2000.
22. Mazda T, Yamamoto H, Fujimura M, and Fujimiya M. Gastric distension-induced release of 5-HT stimulates c-fos expression in specific brain nuclei via 5-HT3 receptors in conscious rats. Am J Physiol Gastrointest Liver Physiol 287: G228-G235, 2004.
23. Mazzola-Pomietto P, Aulakh CS, and Murphy DL. Temperature, food intake, and locomotor activity effects of a 5-HT3 receptor agonist and two 5-HT3 receptor antagonists in rats. Psychopharmacology (Berl) 121: 488-493, 1995.
24. Moran TH and Kinzig KP. Gastrointestinal satiety signals. II. Cholecystokinin. Am J Physiol Gastrointest Liver Physiol 286: G183-G188, 2004.
25. Phillips RJ and Powley TL. Gastric volume rather than nutrient content inhibits food intake. Am J Physiol Regul Integr Comp Physiol 271: R766-R769, 1996.
26. Powley TL and Phillips RJ. Gastric satiation is volumetric, intestinal satiation is nutritive. Physiol Behav 82: 69-74, 2004.
27. Raybould HE, Glatzle J, Robin C, Meyer JH, Phan T, Wong H, and Sternini C. Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying. Am J Physiol Gastrointest Liver Physiol 284: G367-G372, 2003.
28. Ritter RC. Gastrointestinal mechanisms of satiation for food. Physiol Behav 81: 249-273, 2004.
29. Schwartz GJ, McHugh PR, and Moran TH. Pharmacological dissociation of responses to CCK and gastric loads in rat mechanosensitive vagal afferents. Am J Physiol Regul Integr Comp Physiol 267: R303-R308, 1994.
30. Simansky KJ. 5-HT receptor subtypes influencing feeding and drinking: focus on the periphery. In: Drug Receptor Subtypes and Ingestive Behavior, edited by Cooper SJ and Clifton PG. New York: Academic, 1996.
31. Stallone D, Nicolaidis S, and Gibbs J. Cholecystokinin-induced anorexia depends on serotoninergic function. Am J Physiol Regul Integr Comp Physiol 256: R1138-R1141, 1989.
32. van der Hoek GA and Cooper SJ. Ondansetron, a selective 5-HT3 receptor antagonist, reduces palatable food consumption in the nondeprived rat. Neuropharmacology 33: 805-811, 1994.
33. Walsh BT, Zimmerli E, Devlin MJ, Guss J, and Kissileff HR. A disturbance of gastric function in bulimia nervosa. Biol Psychiatry 54: 929-933, 2003.