A CMOS, fully integrated sensor for electronic detection of DNA hybridization

IEEE Electron Device Letters

Volumn 27, Issue 7, 2006, Pages 595-597

  Barbaro, Massimo ^a   Bonfiglio, Annalisa ^a,b   Raffo, Luigi ^a   Alessandrini, Andrea ^b   Facci, Paolo ^b   Barák, Imrich ^c  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b INFM   (Italy)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

CMOS biosensor; Deoxyribonucleic acid (DNA) chip; Fully electronic DNA detection

Indexed keywords

CMOS INTEGRATED CIRCUITS; DNA; ELECTRIC CHARGE; GATES (TRANSISTOR); MOS DEVICES;

DNA HYBRIDIZATION; FLOATING-GATE MOS TRANSISTOR; FULLY ELECTRONIC DNA DETECTION;

BIOSENSORS;

EID: 33745650512     PISSN: 07413106     EISSN: None     Source Type: Journal    
DOI: 10.1109/LED.2006.876303     Document Type: Article

References (12)

1. S. Moore, "Making chips to probe genes," IEEE Spectr., vol. 38, no. 3, pp. 54-60, Mar. 2001.
2. R. Moeller and W. Fritsche, "Chip-based electrical detection of DNA," Proc. Inst. Elect. Eng. - Nanobiotechnol., vol. 152, no. 1, pp. 47-51, Feb. 2005.
3. F. Caruso, E. Rodda, and D. Neil, "Quartz crystal microbalance study of DNA immobilization and hybridization for nucleic acid sensor development," Anal. Chem., vol. 69, no. 11, pp. 2043-2049, Jun. 1997.
4. M. Su, S. Li, and V. P. Dravid, "Micro-cantilever resonance-based DNA detection with nanoparticle probes," Appl. Phys. Lett., vol. 82, no. 20, pp. 3562-3564, May 2003.
5. M. Schienle, C. Paulus, A. Frey, F. Hoffmann, B. Holzapfl, P. Schindler-Bauer, and R. Thewes, "A fully electronic DNA sensor with 128 positions and in-pixel A/D conversion," IEEE J. Solid State Circuits, vol. 39, no. 12, pp. 689-696, Dec. 2004.
6. J. Fritz, E. B. Cooper, S. Gaudet, P. K. Sorger, and S. R. Manalis, "Electronic detection of DNA by its intrinsic molecular charge," Proc. Nat. Acad. Sci., vol. 99, no. 22, pp. 14142-14146, Oct. 2002.
7. D.-S. Kim, Y.-T. Jeong, H.-Y. Park, J.-K. Shin, P. Choi, and J.-H. Lee, "An FET-type charge sensor for highly sensitive detection of DNA sequence," Biosens. Bioelectron., vol. 20, no. 1, pp. 69-74, Jul. 2004.
8. F. Pouthas, C. Gentil, D. Côte, and U. Bockelmann, "DNA detection on transistor arrays following mutation-specific enzymatic amplification," Appl. Phys. Lett., vol. 84, no. 9, pp. 1594-1596, Mar. 2004.
9. P. Bergveld, "Thirty years of ISFETOLOGY: What happened in the past 30 years and what may happen in the next 30 years," Sens. Actuators, vol. 88, no. 1, pp. 1-20, Jan. 2003.
10. M. Barbaro, A. Bonfiglio, and L. Raffo, "A charge-modulated FET for detection of biomolecular processes: Conception, modeling and simulation," IEEE Trans. Electron Devices, vol. 53, no. 1, pp. 158-166, Jan. 2006.
11. A. Alessandrini, V. De Renzi, L. Berti, I. Barak, and P. Facci, "Chemically homogeneous, silylated surface for effective DNA binding and hybridization," Surf. Sci., vol. 582, no. 1-3, pp. 202-208, May 2005.
12. L. Shifeng and S. Chen, "Polydimethylsiloxane fluidic interconnects for microfluidic systems," IEEE Trans. Adv. Packag., vol. 26, no. 3, pp. 242-247, Aug. 2003.