Real-time tumor tracking using implanted positron emission markers: Concept and simulation study

Medical Physics

Volumn 33, Issue 7, 2006, Pages 2598-2609

  Xu, Tong ^a   Wong, Jerry T ^a   Shikhaliev, Polad M ^a   Ducote, Justin L ^a   Al Ghazi, Muthana S ^a   Molloi, Sabee ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Organ motion; Radiation therapy; Real time tracking

Indexed keywords

ELECTRONS; ERRORS; ISOTOPES; MAXIMUM PRINCIPLE; MONTE CARLO METHODS; OPTICAL SENSORS; POSITRONS; RADIOTHERAPY; RESPIRATORY MECHANICS; TRACKING (POSITION); TUMORS;

EXPECTATION - MAXIMIZATIONS; LOCALIZATION ALGORITHM; ORGAN MOTION; POSITION-SENSITIVE DETECTORS; POSITRON-EMITTING ISOTOPES; REAL TIME TRACKING; REAL-TIME TUMOR TRACKING; TUMOR TRACKING SYSTEM;

MOTION TRACKING;

ARSENIC; IODINE 124; ISOTOPE; RUBIDIUM; RUBIDIUM 84; UNCLASSIFIED DRUG;

ABDOMINAL TUMOR; ALGORITHM; ARTICLE; BREATHING; FIELD OF VIEW; GAMMA RADIATION; LUNG TUMOR; POSITRON; PRIORITY JOURNAL; RADIATION DETECTOR; RADIATION DOSE; RADIATION FIELD; RADIATION HAZARD; RADIATION SCATTERING; RADIOSENSITIVITY; RADIOTHERAPY; RISK REDUCTION; SIMULATION; TUMOR DIAGNOSIS; TUMOR LOCALIZATION; X RAY;

EID: 33745636800     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.2207213     Document Type: Article

References (48)

1. IMRT-CWG, " Intensity-modulated radiotherapy: Current status and issues of interest., " Int. J. Radiat. Oncol., Biol., Phys. 51, 880-914 (2001).
2. T. R. Mackie, T. Holmes, S. Swerdloff, P. Reckwerdt, J. O. Deasy, J. Yang, B. Paliwal, and T. Kinsella, " Tomotherapy: A new concept for the delivery of dynamic conformal radiotherapy., " Med. Phys. 20, 1709-1719 (1993).
3. C. X. Yu, " Intensity-modulated arc therapy with dynamic multileaf collimation: An alternative to tomotherapy., " Phys. Med. Biol. 40, 1435-1449 (1995).
4. J. S. Kuo, C. Yu, Z. Petrovich, and M. L. Apuzzo, " The CyberKnife stereotactic radiosurgery system: Description, installation, and an initial evaluation of use and functionality., " Neurosurgery 53, 1235-1239 (2003).
5. C. C. Ling, J. Humm, S. Larson, H. Amols, Z. Fuks, S. Leibel, and J. A. Koutcher, " Towards multidimensional radiotherapy (MD-CRT): Biological imaging and biological conformality., " Int. J. Radiat. Oncol., Biol., Phys. 47, 551-560 (2000).
6. G. Starkschall, K. M. Forster, K. Kitamura, A. Cardenas, S. L. Tucker, and C. W. Stevens, " Correlation of gross tumor volume excursion with potential benefits of respiratory gating., " Int. J. Radiat. Oncol., Biol., Phys. 60, 1291-1297 (2004).
7. S. C. Davies, A. L. Hill, R. B. Holmes, M. Halliwell, and P. C. Jackson, " Ultrasound quantitation of respiratory organ motion in the upper abdomen., " Br. J. Radiol. 67, 1096-1102 (1994).
8. C. S. Ross, D. H. Hussey, E. C. Pennington, W. Stanford, and J. F. Doornbos, " Analysis of movement of intrathoracic neoplasms using ultrafast computerized tomography., " Int. J. Radiat. Oncol., Biol., Phys. 18, 671-677 (1990).
9. N. Koch, H. H. Liu, G. Starkschall, M. Jacobson, K. Forster, Z. Liao, R. Komaki, and C. W. Stevens, " Evaluation of internal lung motion for respiratory-gated radiotherapy using MRI: Part I-correlating internal lung motion with skin fiducial motion., " Int. J. Radiat. Oncol., Biol., Phys. 60, 1459-1472 (2004).
10. J. D. Hoisak, K. E. Sixel, R. Tirona, P. C. Cheung, and J. P. Pignol, " Correlation of lung tumor motion with external surrogate indicators of respiration., " Int. J. Radiat. Oncol., Biol., Phys. 60, 1298-1306 (2004).
11. C. Ozhasoglu and M. J. Murphy, " Issues in respiratory motion compensation during external-beam radiotherapy., " Int. J. Radiat. Oncol., Biol., Phys. 52, 1389-1399 (2002).
12. R. I. Berbeco, S. Nishioka, H. Shirato, G. T. Chen, and S. B. Jiang, " Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates., " Phys. Med. Biol. 50, 3655-3667 (2005).
13. H. Shirato, S. Shimizu, T. Kunieda, K. Kitamura, M. van Herk, K. Kagei, T. Nishioka, S. Hashimoto, K. Fujita, H. Aoyama, K. Tsuchiya, K. Kudo, and K. Miyasaka, " Physical aspects of a real-time tumor-tracking system for gated radiotherapy., " Int. J. Radiat. Oncol., Biol., Phys. 48, 1187-1195 (2000).
14. H. Shirato, M. Oita, K. Fujita, Y. Watanabe, and K. Miyasaka, " Feasibility of synchronization of real-time tumor-tracking radiotherapy and intensity-modulated radiotherapy from viewpoint of excessive dose from fluoroscopy., " Int. J. Radiat. Oncol., Biol., Phys. 60, 335-341 (2004).
15. P. J. Keall, A. D. Todor, S. S. Vedam, C. L. Bartee, J. V. Siebers, V. R. Kini, and R. Mohan, " On the use of EPID-based implanted marker tracking for 4D radiotherapy., " Med. Phys. 31, 3492-3499 (2004).
16. P. G. Seiler, H. Blattmann, S. Kirsch, R. K. Muench, and C. Schilling, " A novel tracking technique for the continuous precise measurement of tumour positions in conformal radiotherapy., " Phys. Med. Biol. 45, N103-110 (2000).
17. J. M. Balter, J. N. Wright, L. J. Newell, B. Friemel, S. Dimmer, Y. Cheng, J. Wong, E. Vertatschitsch, and T. P. Mate, " Accuracy of a wireless localization system for radiotherapy., " Int. J. Radiat. Oncol., Biol., Phys. 61, 933-937 (2005).
18. U. Topal and B. Ediz, " Transthoracic needle biopsy: Factors effecting risk of pneumothorax., " Eur. J. Radiol. 48, 263-267 (2003).
19. E. Sajo and M. L. Williams, " Embedded radiation emitter for the localization and dosimetry of brachytherapy seed implants., " United States Patent 6,761,679, July 13, 2004.
20. D. J. Parker, C. J. Broadbent, P. Fowles, M. R. Hawkesworth, and P. Mcneil, " Positron emission particle tracking-A technique for studying flow within engineering equipment., " Nucl. Instrum. Methods Phys. Res. A 326, 592-607 (1993).
21. D. J. Parker, R. N. Forster, P. Fowles, and P. S. Takhar, " Positron emission particle tracking using the new Birmingham positron camera., " Nucl. Instrum. Methods Phys. Res. A 477, 540-545 (2002).
22. T. Neicu, H. Shirato, Y. Seppenwoolde, and S. B. Jiang, " Synchronized moving aperture radiation therapy (SMART): Average tumour trajectory for lung patients., " Phys. Med. Biol. 48, 587-598 (2003).
23. L. Papiez, D. Rangaraj, and P. J. Keall, " Real-time DMLC IMRT delivery for mobile and deforming targets., " Med. Phys. 32, 3037-3048 (2005).
24. S. B. Koebel and P. L. McHenry, " Myocardial blood flow. Measurement by a coincidence counting system and single bolus of 84Rb., " Arch Intern Med. 127, 767-772 (1971).
25. D. Boettcher, G. Corsini, C. G. Daniels, C. Cowan, and R. J. Bing, " Determination of myocardial blood flow in the anesthetized dog after a bolus of 84Rb., " J. Nucl. Med. 10, 83-92 (1969).
26. J. D. Kimpe, R. Cornelis, L. Mees, and R. Vanholder, " Basal metabolism of intraperitoneally injected carrier-free 74As-labeled arsenate in rabbits., " Fundam. Appl. Toxicol. 34, 240-248 (1996).
27. G. Sundaresan, P. J. Yazaki, J. E. Shively, R. D. Finn, S. M. Larson, A. A. Raubitschek, L. E. Williams, A. F. Chatziioannou, S. S. Gambhir, and A. M. Wu, " 124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice., " J. Nucl. Med. 44, 1962-1969 (2003).
28. S. Robinson, P. J. Julyan, D. L. Hastings, and J. Zweit, " Performance of a block detector PET scanner in imaging non-pure positron emitters-modelling and experimental validation with 124I., " Phys. Med. Biol. 49, 5505-5528 (2004).
29. O. Gundogdu, " Positron emission tomography particle tracking using cluster analysis., " Nucl. Instrum. Methods Phys. Res. A 534, 562-576 (2004).
30. S. Agostinelli, " GEANT4-A simulation toolkit., " Nucl. Instrum. Methods Phys. Res. A 506, 250-303 (2003).
31. K. Iwata, R. G. Greaves, and C. M. Surko, " Gamma-ray spectra from positron annihilation on atoms and molecules., " Phys. Rev. A 55, 3586-3604 (1997).
32. O. Chibani and C. M. Ma, " Photonuclear dose calculations for high-energy photon beams from Siemens and Varian linacs., " Med. Phys. 30, 1990-2000 (2003).
33. Y. Z. Wang, M. D. C. Evans, and E. B. Podgorsak, " Characteristics of induced activity from medical linear accelerators., " Med. Phys. 32, 2899-2910 (2005).
34. J. H. Hubbell and S. M. Seltzer, " Tables of x-ray mass attenuation coefficient and mass energy absorption coefficients 1 keV to 20 MeV for elements Z=1 to 92 and 48 additional substances of dosimetric interest., " NIST: Gaithersburg, 1995, p. 111.
35. R. Barquero, R. Mendez, H. R. Vega-Carrillo, M. P. Iniguez, and T. M. Edwards, " Neutron spectra and dosimetric features around an 18 mv linac accelerator., " Health Phys. 88, 48-58 (2005).
36. R. Y. Zhu, H. Stone, H. Newman, T. Q. Zhou, H. R. Tan, and C. F. He, " A study on radiation-damage in doped BGO crystals., " Nucl. Instrum. Methods Phys. Res. A 302, 69-75 (1991).
37. S. K. Sahu, K. C. Peng, H. C. Huang, C. H. Wang, Y. H. Chang, W. S. Hou, K. Ueno, F. I. Chou, and Y. Y. Wei, " Radiation hardness of undoped BGO crystals., " Nucl. Instrum. Methods Phys. Res. A 388, 144-148 (1997).
38. V. V. Yanovsky, V. A. Chizhov, and V. M. Skorikov, " BGO crystals-Radiation hard scintillators., " Nucl. Instrum. Methods Phys. Res. A 309, 596-597 (1991).
39. Z. Y. Wei, R. Y. Zhu, H. Newman, and Z. W. Yin, " Radiation-Resistance and Fluorescence of Europium Doped BGO Crystals., " Nucl. Instrum. Methods Phys. Res. A 297, 163-168 (1990).
40. ESTAR, Stopping Powers and Ranges for Electrons, National Institute of Standards and Technology (NIST), http://physics.nist.gov/PhysRefData/Star/Text/ ESTAR.html.
41. H. Shirato, " Feasibility of insertion/implantation of 2.0-mm -diameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy., " Int. J. Radiat. Oncol., Biol., Phys. 56, 240-247 (2003).
42. M. Imura, K. Yamazaki, H. Shirato, R. Onimaru, M. Fujino, S. Shimizu, T. Harada, S. Ogura, H. Dosaka-Akita, K. Miyasaka, and M. Nishimura, " Insertion and fixation of fiducial markers for setup and tracking of lung tumors in radiotherapy., " Int. J. Radiat. Oncol., Biol., Phys. 63, 1442-1447 (2005).
43. B. H. Heintz, R. E. Wallace, and J. M. Hevezi, " Comparison of I-125 sources used for permanent interstitial implants., " Med. Phys. 28, 671-682 (2001).
44. M. L. Hernando, L. B. Marks, G. C. Bentel, S. M. Zhou, D. Hollis, S. K. Das, M. Fan, M. T. Munley, T. D. Shafman, M. S. Anscher, and P. A. Lind, " Radiation-induced pulmonary toxicity: A dose-volume histogram analysis in 201 patients with lung cancer., " Int. J. Radiat. Oncol., Biol., Phys. 51, 650-659 (2001).
45. T. Uno, K. Isobe, H. Kawakami, N. Ueno, T. Kawata, S. Yamamoto, Y. Sekine, A. Iyoda, T. Iizasa, T. Fujisawa, N. Shigematsu, and H. Ito, " Dose-volume factors predicting radiation pneumonitis in patients receiving salvage radiotherapy for postlobectomy locoregional recurrent non-small-cell lung cancer., " International J. Clinical Oncology 11, 55-59 (2006).
46. E. H. Smith, " The hazards of fine-needle aspiration biopsy., " Ultrasound Med. Biol. 10, 629-634 (1984).
47. D. Ayar, B. Golla, J. Y. Lee, and H. Nath, " Needle-track metastasis after transthoracic needle biopsy., " J. Thorac. Imaging 13, 2-6 (1998).
48. S. S. Bastacky, P. C. Walsh, and J. I. Epstein, " Needle biopsy associated tumor tracking of adenocarcinoma of the prostate., " J. Urol. (Paris) 145, 1003-1007 (1991).