Genetic polymorphisms at FCER1B and PAI-1 and asthma susceptibility

Clinical and Experimental Allergy

Volumn 36, Issue 7, 2006, Pages 872-876

  Hizawa, N ^a   Maeda, Y ^a   Konno, S ^a   Fukui, Y ^a   Takahashi, D ^a   Nishimura, M ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Bronchial asthma; Fc RI ; Gene gene interaction; PAI 1

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1;

ADULT; ARTICLE; ASTHMA; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENE; GENE ACTIVATION; GENE INTERACTION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HIGH RISK POPULATION; HUMAN; JAPAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; PAI1 GENE; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR AFFINITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ASTHMA; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; RECEPTORS, IGE; VARIATION (GENETICS);

EID: 33745636308     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2006.02413.x     Document Type: Article

References (18)

1. Kucharewicz I, Kowal K, Buczko W, Bodzenta-Lukaszyk A. The plasmin system in airway remodeling. Thromb Res 2003; 112:1-7.
2. Cho SH, Tam SW, Demissie-Sanders S, Filler SA, Oh CK. Production of plasminogen activator inhibitor-1 by human mast cells and its possible role in asthma. J Immunol 2000; 165:3154-61.
3. Oh CK, Ariue B, Alban RF, Shaw B, Cho SH. PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model. Biochem Biophys Res Commun 2002; 294:1155-60.
4. Eriksson P, Kallin B, van 't Hooft FM, Bavenholm P, Hamsten A. Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction. Proc Natl Acad Sci USA 1995; 92:1851-5.
5. Cho SH, Hall IP, Wheatley A et al. Possible role of the 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene in the development of asthma. J Allergy Clin Immunol 2001; 108:212-4.
6. Buckova D, Izakovicova Holla L, Vacha J. Polymorphism 4G/5G in the plasminogen activator inhibitor-1 (PAI-1) gene is associated with IgE-mediated allergic diseases and asthma in the Czech population. Allergy 2002; 57:446-8.
7. Shirakawa T, Li A, Dubowitz M et al. Association between atopy and variants of the β subunit of the high affinity immunoglobulin E receptor. Nat Genet 1994; 7:125-9.
8. Sandford AJ, Shirakawa T, Moffatt MF et al. Localisation of atopy and beta subunit of high-affinity IgE receptor (FcεRI) on chromosome 11q. Lancet 1993; 341:332-4.
9. Hizawa N, Yamaguchi E, Jinushi E, Kawakami Y. A common FCER1B gene promoter polymorphism influences total serum IgE levels in a Japanese population. Am J Respir Crit Care Med 2000; 161 (Part 1):906-9.
10. Nishiyama C, Akizawa Y, Nishiyama M et al. Polymorphisms in the FcεRI beta promoter region affecting transcription activity: a possible promoter-dependent mechanism for association between FcεRI beta and atopy. J Immunol 2004; 173:6458-64.
11. Traherne JA, Hill MR, Hysi P et al. LD mapping of maternally and non-maternally derived alleles and atopy in FcεRI-beta. Hum Mol Genet 2003; 12:2577-85.
12. Xu J, Meyers DA, Ober C et al. Collaborative study on the genetics of asthma. Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma. Am J Hum Genet 2001; 68:1437-46.
13. Howard TD, Koppelman GH, Xu J et al. Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma. Am J Hum Genet 2002; 70:230-6.
14. Hizawa N, Yamaguchi E, Konno S, Tanino Y, Jinushi E, Nishimura M. A functional polymorphism in the RANTES gene promoter is associated with the development of late-onset asthma. Am J Respir Crit Care Med 2002; 166:686-90.
15. Hizawa N, Yamaguchi E, Takahashi D, Nishihira J, Nishimura M. Functional polymorphisms in the promoter region of macrophage migration inhibitory factor and atopy. Am J Respir Crit Care Med 2004; 169:1014-8.
16. Hizawa N, Yamaguchi E, Jinushi E, Konno S, Kawakami Y, Nishimura M. Increased total serum IgE levels in patients with asthma and promoter polymorphisms at CTLA4 and FCER1B. J Allergy Clin Immunol 2001; 108:74-9.
17. Matthay MA, Clements JA. Coagulation-dependent mechanisms and asthma. J Clin Invest 2004; 114:20-3.
18. Tchougounova E, Pejler G, Abrink M. The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover. J Exp Med 2003; 198:423-31.