Ischemic training and immunosuppressive agents reduce the intensity of ischemic reperfusion injury after kidney transplantation

Experimental and Clinical Transplantation

Volumn 4, Issue 1, 2006, Pages 439-444

  Treska, Vladislav ^a   Molacek, Jiri ^a   Kobr, Jiri ^a   Racek, Jaroslav ^a   Trefil, Ladislav ^a   Hes, Ondrej ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Graft function; Immunosuppression; Ischemia reperfusion injury; Ischemic training; Kidney transplantation

Indexed keywords

ANTIOXIDANT; CYTOKINE; GLUTATHIONE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 6; INTERLEUKIN 8; MALONALDEHYDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; REACTIVE OXYGEN METABOLITE; TACROLIMUS; TUMOR NECROSIS FACTOR ALPHA;

ACUTE GRAFT REJECTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CLAMP; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MARKER; DISEASE SEVERITY; DRUG DOSE REGIMEN; ERYTHROCYTE; FOLLOW UP; HETEROTOPIC TRANSPLANTATION; HISTOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY INTERSTITIUM; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; KIDNEY VEIN; MALE; NEPHRITIS; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; RENAL PROTECTION; REPERFUSION INJURY; SWINE; TRAINING;

ANIMALS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MALONDIALDEHYDE; MYCOPHENOLIC ACID; PREOPERATIVE CARE; REPERFUSION INJURY; SWINE; TACROLIMUS; TREATMENT OUTCOME;

EID: 33745625610     PISSN: 13040855     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Treska V, Molacek J, Kuntscher V, Liska V, Kobr J, Racek J, Kormunda S. Immunosuppressive agents have an influence on ischemia-reperfusion injury in kidneys procured from a non-heart-beating donor: experimental study. Transplant Proc 2004; 36: 2931-2934
2. Treska V, Kuntscher V, Molacek J, Kobr J, Racek J, Trefil L. Can ischemia-reperfusion syndrome in transplanted kidneys procured from non-heart-beating donors be influenced by adding selenium into the reperfusion solution? An experimental study. Transplant Proc 2003; 35: 3125-3127
3. Benett W. Immunosuppression with mycophenolic acid: one size does not fit all. J Am Soc Nephrol 2003; 14: 2414-2418
4. Danovitch GM. Immunosuppressant induced metabolic toxicities. Transplant Rev 2000; 14: 65-72
5. Fuller TF, Freise CE, Feng S, Niemann CU. Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury. Transplant Proc 2005; 37: 377-378
6. Torras J, Herrero-Fresneda I, Lloberas N, Riera M, Ma Cruzado J, Ma Grinyo J. Promising effects of ischemic preconditioning in renal transplantation. Kidney Int 2002; 61: 2218-2227
7. Jefayri MK, Grace PA, Mathie RT. Attenuation of reperfusion injury by renal ischaemic preconditioning: the role of nitric oxide. BJU Int 2000; 85: 1007-1013
8. Nakano A, Liu GS, Heusch G, Downey JM, Cohen MV. Exogenous nitric oxide can trigger a preconditioned state through a free radical mechanism, but endogenous nitric oxide is not a trigger of classical ischemic preconditioning. J Mol Cell Cardiol 2000; 32: 1159-1167
9. Yamashita J, Ogata M, Itoh M, Yamasowa H, Shimeda Y, Takaoka M, Matsumura Y. Role of nitric oxide in the renal protective effects of ischemic preconditioning. J Cardiovasc Pharmacol 2003; 42: 419-427
10. Jentzsch AM, Bachmann H, Furst P, Biesalski HK. Improved analysis of malondialdehyde in human body fluids. Free Radic Biol Med 1996; 20: 251-257
11. Treska V, Hasman D, Hes O, Kuntscher V. Donors with non-beating hearts - a new possibility in expanding the kidney donor program. Rozhl Chir 2000; 79: 622-625
12. Treska V, Hasman D, Topolcan O, Hes O. Cytosolic concentration of cytokines in kidneys from non-heart beating donors. Acta Univ Palacki Olomouc Fac Med 2000; 143: 103
13. Dragun D, Hoff U, Park JK, Qun Y, Schneider W, Luft FC, Haller H. Prolonged cold preservation augments vascular injury independent of renal transplant immunogenicity and function. Kidney Int 2001; 60: 1173-1181
14. Kauppinen H, Soots A, Krogerus L, Loginov R, Holma K, Ahonen J, Lautenschlager I. Sequential analysis of adhesion molecules and their ligands in rat renal allografts during the development of chronic rejection. Transpl Int 2000; 13: 247-254
15. Norio K, Wikstrom M, Salmela K, Kyllonen L, Lindgren L. Ascorbic acid against reperfusion injury in human renal transplantation. Transpl Int 2003; 16: 480-485
16. Bonventre JV. Pathophysiology of ischemic acute renal failure. Inflammation, lung-kidney cross-talk, and biomarkers. Contrib Nephrol 2004; 144: 19-30
17. Kelly KJ. Heat shock (stress response) proteins and renal ischemia/ reperfusion injury. Contrib Nephrol 2005; 148: 86-106
18. Donnahoo KK, Meng X, Ao L, Ayala A, Shames BD, Cain MP, et al. Differential cellular immunolocalization of renal tumour necrosis factor-alpha production during ischaemia versus endotoxaemia. Immunology 2001; 102: 53-58
19. Nakao A, Neto JS, Kanno S, Stolz DB, Kimizuka K, Liu F, et al. Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant 2005; 5: 282-291
20. Treska V, Racek J, Kuntscher V, Hasman D, Kobr J, Molacek J, et al. Plasma and tissue levels of free oxygen radicals in recipients of kidneys from non-heart-beating donors: does recipient pretreatment with antioxidant drugs make sense? An experimental study in pigs. Transplant Proc 2002; 34: 3060-3064
21. Valentin JF, Bruijn JA, Paul LC. Donor treatment with mycophenolate mofetil: protection against ischemia-reperfusion injury in the rat. Transplantation 2000; 69: 344-350
22. Fuller TF, Freise CE, Serkova N, Niemann CU, Olson JL, Feng S. Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury. Transplantation 2003; 76: 1594-1599
23. El-Asir L, Wilson CH, Talbot D. Interleukin 2 receptor blockers may directly inhibit lymphocyte mediated ischaemia reperfusion injury. Transpl Int 2005; 18: 1116
24. Faubel S, Edelstein CL. Caspases as drug targets in ischemic organ injury. Curr Drug Targets Immune Endocr Metabol Disord 2005; 5: 269-287
25. Burne-Taney MJ, Yokota-Ikeda N, Rabb H. Effects of combined T-and B-cell deficiency on murine ischemia reperfusion injury. Am J Transplant 2005; 5: 1186-1193
26. Barrier A, Olaya N, Chiappini F, Roser F, Scatton O, Artus C, et al. Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion. FASEB J 2005; 19: 1617-1626
27. Net M, Valero R, Almenara R, Barros P, Capdevila L, Lopez-Boado MA, et al. The effect of normothermic recirculation is mediated by ischemic preconditioning in NHBD liver transplantation. Am J Transplant 2005; 5: 2385-2392
28. Chouker A, Martignoni A, Schauer RJ, Rau HG, Volk A, Heizmann O, et al. Ischemic preconditioning attenuates portal venous plasma concentrations of purines follovving warm liver ischemia in man. Eur Surg Res 2005; 37: 144-152
29. Azoulay D, Del Gaudio M, Andreani P, Ichai P, Sebag M, Adam R, et al. Effects of 10 minutes of ischemic preconditioning of the cadaveric liver on the graft's preservation and function: the ying and the yang. Ann Surg 2005; 242: 133-139
30. Fuller TF, Freise CE, Feng S, Niemann CU. Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury. Transplant Proc 2005; 37: 377-378
31. van der Woude FJ, Schnuelle P, Yard BA. Preconditioning strategies to limit graft immunogenicity and cold ischemic organ injury. J Invest Med 2004; 52: 323-329
32. Treska V, Kuntscher V, Hasman D, Neprasova P, Kobr J, Racek J, et al. Importance of selenium for the influence of ischemia-reperfusion syndrome after kidney transplantation from a non-heart-beating donor in a pig model. Transplant Proc 2002; 34: 3057-3059