An overview of factors affecting the disposition of intramammary preparations used to treat bovine mastitis

Journal of Veterinary Pharmacology and Therapeutics

Volumn 29, Issue 4, 2006, Pages 237-241

  Gehring, R ^a   Smith, G W ^b  

^a KANSAS STATE UNIVERSITY   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CEFAPIRIN; CEFTIOFUR; CLOXACILLIN; DIHYDROSTREPTOMYCIN; ERYTHROMYCIN; HETACILLIN; NOVOBIOCIN; OXYTETRACYCLINE; PENICILLIN G; PIRLIMYCIN;

ANTIMICROBIAL THERAPY; CATTLE DISEASE; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG FORMULATION; DRUG MILK LEVEL; DRUG SAFETY; ENVIRONMENTAL FACTOR; FOOD CONTAMINATION; FOOD SAFETY; LIPID SOLUBILITY; MAMMARY GLAND; MASTITIS; MATHEMATICAL ANALYSIS; MILK; MILK PRODUCTION; NONHUMAN; PKA; PRIORITY JOURNAL; REVIEW;

ANIMALS; ANTI-BACTERIAL AGENTS; CATTLE; DRUG ADMINISTRATION ROUTES; FEMALE; LACTATION; MAMMARY GLANDS, ANIMAL; MASTITIS, BOVINE;

BOS TAURUS;

EID: 33745601076     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2006.00750.x     Document Type: Review

References (18)

1. Ehinger, A.M. & Kietzmann, M. (2000a) Tissue distribution of benzylpenicillin after intramammary administration in the isolated perfused bovine udder. Journal of Veterinary Pharmacology Therapeutics, 23, 303-310.
2. Ehinger, A.M. & Kietzmann, M. (2000b) Tissue distribution of oxacillin and ampicillin in the isolated perfused bovine udder. Journal of Veterinary Medicine A, Physiology, Pathology, Clinical Medicine, 47, 157-168.
3. Ehinger, A.M., Ehinger, B. & Kietzmann, M. (2001) Pharmaceutical and pharmacological remarks upon using dry-off preparations in dairy cows. Tierarztliche Praxis, 29, 114-121.
4. Erskine, R.J., Wagner, S & DeGraves, F.J. (2003) Mastitis therapy and pharmacology. Veterinary Clinics of North America Food Animal Practice, 19, 109-138, vi.
5. Gips, M. & Soback, S. (1999) Norfloxacin pharmacokinetics in lactating cows with sub-clinical and clinical mastitis. Journal of Veterinary Pharmacology and Therapeutics, 22, 202-208.
6. Gruet, P., Maincent, P., Berthelot, X. & Kaltsatos, V. (2001) Bovine mastitis and intramammary drug delivery: review and perspectives. Advanced Drug Delivery Reviews, 50, 245-259.
7. Jacobs, J., Klasens, M. & Pennings, A. (1971) Elimination of penicillin from normal and mastitic udder quarters after intramammary treatment. Tijdschrift der Diergenesskunde, 96, 721-730.
8. McManaman, J.L. & Neville, M.C. (2003) Mammary physiology and milk secretion. Advanced Drug Delivery Reviews, 55, 629-641.
9. Mercer, H.D., Geleta, J.N., Schultz, E.J. & Wright, W.W. (1970) Milk-out rates for antibiotics in intramammary infusion products used in the treatment of bovine mastitis: relationship of somatic cell counts, milk production level, and drug vehicle. American Journal of Veterinary Research, 31, 1549-1560.
10. Mercer, H.D., Geleta, J.N., Porteous, L.A. & Condon, R.J. (1974) Excretion of penicillin G and dihydrostreptomycin from quarters of cows with experimentally induced staphylococcal mastitis. American Journal of Veterinary Research, 35, 1191-1196.
11. Smith, G.W., Gehring, R., Riviere, J.E., Yeatts, J.L. & Baynes, R.E. (2004) Elimination kinetics of ceftiofur hydrochloride after intramammary administration in lactating dairy cows. Journal of the American Veterinary Medical Association, 224, 1827-1830.
12. Sweeney, R.W., Fennell, M.A., Smith, C.M. & Bardalaye, P.C. (1996) Systemic absorption of gentamicin following intramammary administration to cows with mastitis [correction of mastititis]. Journal of Veterinary Pharmacology Therapeutics, 19, 155-157.
13. Vilim, A., Larocque, L. & Macintosh, A. (1980) Depletion of brilliant blue F.C.F., penicillin G, and dihydrostreptomycin in milk treated does with experimentally induced mastitis. Journal of Food Protection, 43, 356-359.
14. Whittem, T. (1999) Pharmacokinetics and milk discard times of pirlimycin after intramammary infusion: a population approach. Journal of Veterinary Pharmacology Therapeutics, 22, 41-51.
15. Ziv, G. (1980a) Practical pharmacokinetic aspects of mastitis therapy - 3: intramammary treatment. Veterinary Medicine/Small Animal Clinician, 75, 657-670.
16. Ziv, G. (1980b) Drug selection and use in mastitis: systemic vs. local therapy. Journal of the American Veterinary Medical Association, 176, 1109-1115.
17. Ziv, G. & Schultze, W.D. (1982) Pharmacokinetics of polymyxin B administered via the bovine mammary gland. Journal of Veterinary Pharmacology Therapeutics, 5, 123-129.
18. Ziv, G. & Sulman, F.G. (1975) Absorption of antibiotics by the bovine udder. Journal of Dairy Science, 58, 1637-1644.